Previous research that investigated asymmetric effects of exchange rate changes on the bilateral trade balance of the U.S. with Canada using their aggregate bilateral trade flows did not find support for such effects. In this paper we disaggregate the trade flows of the two countries by commodity and consider experiences of 161 industry that trade between them. After estimating the linear and nonlinear ARDL models we find support for the asymmetric short-run effects in all industries, short-run adjustment asymmetry in 69 industries, significant short-run cumulative or impact asymmetry in 37 industries and significant long-run asymmetric effects in 62 industries. Small as well as large industries were in the list.