Effectiveness Of Therapy In Children Research Articles

Clinical Accommodations for Children With Co-Occurring Developmental Language Disorder and Attention-Deficit/Hyperactivity Disorder

Purpose: Developmental language disorder (DLD) and attention-deficit/hyperactivity disorder (ADHD) are two of the most prevalent disorders in school-age children and are likely to be co-occurring. However, speech-language pathologists (SLPs) may receive limited training regarding strategies for capitalizing on strengths and accommodating the needs of children with ADHD relating to challenges in attention, working memory, behavioral inhibition, and self-regulation in the clinical setting. Therefore, in this tutorial, we describe how the cognitive profile of children with DLD and ADHD may present in the therapy room and review strategies for adapting therapeutic approaches to fit the needs of children with ADHD neurotypes. Method: This tutorial includes a review of research related to linguistic, cognitive, and behavioral differences in children with co-occurring DLD and ADHD. Strategies for accommodations in the therapy room are discussed, and we present a case study to demonstrate how these accommodations can be implemented. Conclusions: SLPs can enhance the effectiveness of therapy for children with co-occurring DLD and ADHD with an awareness of the struggles that children with DLD and ADHD experience in the therapy room. Providing these children with the appropriate accommodations can alleviate difficulties due to neurodivergent traits related to working memory, sustaining and shifting attention, social–emotional perception, behavioral inhibition, and self-regulation that occur along with linguistic difficulties.

Long-term effectiveness of growth hormone therapy in children born small for gestational age: An analysis of LG growth study data.

PurposeGrowth hormone (GH) treatment has been used to improve growth in short children who were born small for gestational age (SGA). The aim of this study was to investigate the long-term efficacy of GH treatment in these children.MethodsData from a multicenter observational clinical trial (ClinicalTrials.gov NCT01604395, LG growth study) were analyzed for growth outcome and prediction model in response to GH treatment. One hundred fifty-two children born SGA were included.ResultsThe mean age of patients born SGA was 7.13 ± 2.59 years. Height standard deviation score (SDS) in patients born SGA increased from -2.55 ± 0.49 before starting treatment to -1.13 ± 0.76 after 3 years of GH treatment. Of the 152 patients with SGA, 48 who remained prepubertal during treatment used model development. The equation describing the predicted height velocity during 1st year of GH treatment is as follows: the predictive height velocity (cm) = 10.95 + [1.12 x Height SDS at initial treatment (score)] + [0.03 x GH dose (ug/kg/day)] + [0.30 x TH SDS at initial treatment (score)] + [0.05 x age (year)] + [0.15 x Weight SDS at initial treatment (score)] ± 1.51 cm.ConclusionsGH treatment improved growth outcome in short children born SGA. We also developed a prediction model that is potentially useful in determining the optimal growth outcome for each child born SGA.Trial registrationClinicalTrials.gov Identifier: NCT01604395.

ART THERAPY ON BULLYING-VICTIMS BEHAVIOR AGED 5-6

This study aims to examine the effectiveness of art therapy on the behavior of children aged 5-6 years who are victims of bullying. Single Subject Research with A-B-A design is the method used. The subject of this study was one early childhood who experienced psychological bullying. This study used a description test, observation, and documentation. The results show that A (1) and A (2) the overall average score of subjects (AL) in Baseline 1 (A1) conditions is 47, which is categorized as poor, on intervention baseline data, it gets 64.2, and after intervention baseline 2 (A2) of 69.3 so that during and after the intervention the results revealed that art therapy was quite good as an intervention for children who were victims of bullying. Thus, the effectiveness of therapy in children who experience bullying is successful. This study recommends using drawing activities to provide intervention against psychological problems in children who are victims of bullying.

ART THERAPY ON BULLYING-VICTIMS BEHAVIOR AGED 5-6

This study aims to examine the effectiveness of art therapy on the behavior of children aged 5-6 years who are victims of bullying. Single Subject Research with A-B-A design is the method used. The subject of this study was one early childhood who experienced psychological bullying. This study used a description test, observation, and documentation. The results show that A (1) and A (2) the overall average score of subjects (AL) in Baseline 1 (A1) conditions is 47, which is categorized as poor, on intervention baseline data, it gets 64.2, and after intervention baseline 2 (A2) of 69.3 so that during and after the intervention the results revealed that art therapy was quite good as an intervention for children who were victims of bullying. Thus, the effectiveness of therapy in children who experience bullying is successful. This study recommends using drawing activities to provide intervention against psychological problems in children who are victims of bullying.

ASSESSMENT OFTHE SEVERITY OF ACUTE OBSTRUCTIVE BRONCHITIS AND BRONCHIOLITIS IN EARLY CHILDREN DEPENDING ON THE LEVEL OF OXIPROLIN IN THE BLOOD

The article presents data on the state of collagen metabolism in terms of oxyproline in the blood, its clinical significance for assessing the severity and outcome of the disease, the criterion for the effectiveness of therapy in children of early age withacute obstructive bronchitis and bronchiolitis. The author recommends to determine the level of free and protein-bound oxyproline in blood plasma, an increase in which reflects the degree of destruction in the bronchopulmonary apparatus. The inclusion of immunomodulin into the basic treatment contributes to an increase in the effectiveness of therapy, a reduction of treatment duration.Keywords: oxyproline, bronchitis and bronchiolitis, immunomodulin, treatment, children

Особливості призначення муколітичної терапії у дітей у постнападному періоді бронхіальної астми

Bronchial asthma is the most common chronic pathology in childhood. Chronic inflammatory process of the respiratory tract forms bronchial hyperreactivity which is manifested by typical clinical symptoms. Like any other chronic disorder, the course of bronchial asthma consists of periods of exacerbation and remission. A productive cough in the post-attack period determines the prescription of mucolytic drugs by doctors to liquefy viscous sputum, to remove it more quickly, especially among the paediatric population. There are different approaches to prescribing mucolytic drugs during exacerbation of symptoms of bronchial asthma in scientific publications. The purpose of the study was to evaluate the clinical effectiveness of mucolytic therapy in children with bronchial asthma to optimize the treatment of disease exacerbations. Material and methods. One hundred two medical records of patients treated for asthma exacerbation in pulmonological department of the Chernivtsi Regional Children Clinical Hospital were analyzed. Four clinical groups were formed depending on the prescription of mucolytic drugs. There were not any significant differences by sex, place of residence, however the average age of patients who were prescribed carbocisteine. It was significantly less than in children of other clinical groups. Results and discussion. It was determined that acetylcysteine and carbocysteine were prescribed to patients on the first day of the productive cough onset. Instead to children of the IV clinical group where ambroxol was prescribed on average 1.6 days before the wet cough onset. The study results showed that the average duration of hospitalization in patients receiving ambroxol was 1.5 days less than in children taking acetylcysteine or carbocysteine. The difference was significant. However, the duration of hospitalization for children of I clinical group was not significant longer in comparison with patients received drugs with mucolytic effect in the complex therapy of asthma exacerbation. Conclusion. Despite the fact that acetylcysteine and carbocysteine were significantly more often prescribed for more severe and pronounced asthma exacerbation a decrease in the relative and absolute risks of longer hospitalization was observed in patients taking carbocysteine

The main aspects of physical therapy in children with bronchial asthma

Purpose. The study of clinical features of the course of bronchial asthma and the study of the effectiveness of the use of therapeutic measures with the involvement of physical therapy in children living in Zaporizhzhia and from the Zaporizhzhia region, taking into account their physical development and indices of the initial vegetative tonus and vegetative provision. Materials and Methods. According to the set task, the first group of observation included 87 children with bronchial asthma (BA) living in Zaporizhzhia, 57 of which were boys and 30 girls, and the second group consisted of 40 children with BA from the Zaporizhzhia region, 24 of which were boys and 16 girls. As a comparison, 56 practically healthy children (31 boys and 25 girls) who formed the control groups (CGs) were examined. Thus, 29 of them (16 boys and 13 girls) from Zaporizhzhia made the CGI and 27 children (15 boys and 12 girls) from Zaporizhzhia region were included in CGII. The average age of the examined children was 11.40 ± 3.68 years. To evaluate the effectiveness of physical therapy in children with bronchial asthma, their catamnestic observation has been conducted for at least 2 years. Statistical data processing was performed by commonly used methods of variation statistics of the licensed software package Statistica for Windows 13 (StatSoft Inc., № JPZ804I382130ARCN10-J). Results. Bronchial asthma in children, irrespective of place of residence, clinical course and severity, was characterized by a mild and moderate persistent course in 50.57% and 40.23 % of urban and 47.50 % and 45.00 % of regional patients with obstructive type of violation of bronchial conduction. Physical development of children with bronchial asthma, grown up in the conditions of district centers, had more often harmonious physical development (85.00 %) than patients from the city (56.32 %) (P < 0.05), and, on the contrary, disharmonious prevailed in urban patients (43.68 %) and was less common in regional (15.00 %) patients, mainly in boys (59.65 % vs. 16.67 %, P < 0.05). In all patients with bronchial asthma, unlike healthy children from control group, eutonia (34.48 % and 42.50 %) was rarely recorded but more often sympathicotonia (33.33 % and 32.50 %) and vagotonia (32.18 % and 25.00 %) with a significant difference with the control group of the regional children with asthma for the hypersympathicotonic version of vegetative provision and in urban areas for sympathoasthenic, asthenosympathetic and hyperdiastolic variants. Conclusions . The use of physical therapy in the treatment of children with bronchial asthma has significantly reduced complaints, disease symptoms, accelerated remission and increased its duration to 24 months and reduced the risk of transformation of the disease into more severe forms.

Effectiveness of postoperative pain therapy in children assessed by their parents – is inadequate analgesia potentially dangerous?

Inadequate pain therapy can lead to negative physical and psychological consequences, increase complications and even mortality. We aimed to assess effectiveness of postoperative analgesia in children from their parents’ point of view. We also wanted to evaluate their degree of satisfaction of postoperative analgesia and to identify areas for improvement. Patients’ parents (n = 85) from Paediatric University Hospital in Warsaw, Poland, took part in our survey. They evaluated pain intensity on five-point Likert Scale and on numerical rating scale (NRS). Mean value of pain on NRS was 4.22 (SD±2,53). On Likert scale the majority of parents described pain intensity as moderate. High percentage (38.82%) of children were in pain while their parents took the survey and only 19% of children did not feel pain at all. In 36 children (42.36%) pain caused sleep disturbances. In same cases non-pharmacological methods of analgesia were effective. Due to inadequate pain relief one of the parents arbitrarily administered a formulation containing paracetamol and codeine. The study revealed low efficacy of analgesia among children of surveyed parents. Their level of satisfaction was inadequately high (91% of them were „very satisfied” or “rather satisfied”). The survey confirmed the need for systematic pain assessment tools. Parental education seems necessary to make them aware that postoperative pain can be treated effectively. Administration of drugs without consulting medical staff is dangerous. It may result in the use of contraindicated agents (as in the case described), drug overdose or unexpected interactions.

Modern ways to improve effectiveness of food allergy treatment in children

Aim. To evaluate the effectiveness and safety of a multi-strain probiotic in children with various clinical manifestations of food allergy. Materials and methods. Under the supervision there were 192 children aged from 3 months to 3 years with skin, gastrointestinal and combined (skingastrointestinal) manifestations of food allergies. Patients of the main group received complex therapy and a multistrain probiotic. Patients in the control group did not receive probiotic. Clinical assessment of symptoms during the treatment was conducted (initially and after 30 days). Results. The use of a multistrain probiotic in children with various clinical manifestations of food allergy during 30 days showed improvement of skin and gastrointestinal symptoms of food allergy. The overall effectiveness of therapy in children of the main group was 80.3% versus 68.6% in the control group. Probiotic tolerance was good; no adverse reactions were noted. Conclusion. The inclusion of a new generation probiotic in the complex therapy of food allergies helps to improve the course of the disease and increase the effectiveness of treatment.

Safety and effectiveness of stoss therapy in children

Safety and effectiveness of stoss therapy in children

Association of CYP3A5 (6986A&gt;G) gene polymorphism with the effectiveness of anti-inflammatory therapy in children with bronchial asthma

Inhaled glucocorticosteroids are the main drugs used to control bronchial asthma in children. P450-cytochrome of 3A (CYP3A) family is involved in their metabolism. CYP3A5-isoenzyme plays the leading role in the respiratory tract. We described 6986A&gt;G polymorphism in the CYP3A5 gene encoding this isoenzyme.Aim of the study. To evaluate the association of CYP3A5 (6986A&gt; G) gene polymorphism with the effectiveness of drugs in children with bronchial asthma.Materials and methods. We examined 108 children from 6 to 17 years with bronchial asthma. The allergist carried out the dynamic outpatient polyclinic follow-up of patients, assessed the symptoms of the disease and corrected the corresponding basic therapy. All children underwent genotyping for the 6986A&gt; G polymorphic marker of the CYP3A5 gene.Results. Ten (9.26%) children were heterozygous for the 6986A&gt; G polymorphic marker of the CYP3A5 gene (AG genotype). The authors obtained statistically significant differences in the frequency of the AG genotype between the patients receiving control therapy for bronchial asthma of the 1st – 2nd stage and the patients with control therapy of the 3rd and higher stages in accordance with GINA criteria (p=0.031). In the group with severe bronchial asthma, the number of heterozygotes for the 6986A&gt; G polymorphic marker of the CYP3A5 gene was significantly higher than among children with a mild course of the disease (p=0.029).Conclusion. The AG genotype and A-allele (CYP3A5 gene, A6986A&gt; G polymorphism) are associated with the need for greater volume of control therapy for bronchial asthma and they are risk factors of a more severe course of the disease.

To study the effectiveness of occupational therapy in children with overweight/obesity and its impact upon quality of life

To study the effectiveness of occupational therapy in children with overweight/obesity and its impact upon quality of life

Evaluation of the Immunological Status and Effectiveness of Therapy in Children with Chronic Virus Hepatitis B

Evaluation of the Immunological Status and Effectiveness of Therapy in Children with Chronic Virus Hepatitis B

Clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis

Background: Olopatadine hydrochloride is one of the most promising agents with a broad range of pharmacological effects. It has both antihistaminic and mast cell stabilizing properties. It is used in various allergic diseases, and its ophthalmic solution is used in allergic conjunctivitis. Aims and Objectives: To assess the clinical effectiveness of olopatadine therapy in children with allergic conjunctivitis. Materials and Methods: This was a prospective interventional study conducted to assess the clinical efficacy and safety of 0.2% olopatadine hydrochloride ophthalmic solution on 49 pediatric allergic conjunctivitis patients. 1-2 drops of the ophthalmic solution were administered once daily in each eye for 6 weeks. Scoring of redness, itching, watering, and photophobia was estimated at baseline, 2 week and 6 weeks. Adverse effects were noted at each visit if any. Results: The mean scores of redness, itching, watering, and photophobia were reduced after 2 weeks of treatment which was statistically significant (P < 0.001). Conclusion: Olopatadine hydrochloride 0.2% once daily administration was effective in reducing ocular signs and symptoms in allergic conjunctivitis in the pediatric population.

Effectiveness of Music Therapy in Children with Neurological Disorders

Effectiveness of Music Therapy in Children with Neurological Disorders

Effectiveness of Vision Therapy for Children With Symptomatic Convergence Insufficiency With or Without Attention Deficit Hyperactivity Disorder

Purpose: Attention Deficit Hyperactivity Disorder (ADHD) is a serious health concern. Not only has ADHD been implicated as factors of academic performance in school children, it has been positively correlated with delinquency and drug use. Likewise, convergence insufficiency (CI) has been correlated with ADHD. Vision Therapy (VT) has recently been shown to improve both symptoms and clinical objective measures of CI. The purpose of this study was to study the effect of VT on visual symptoms and clinical measures for children with symptomatic CI and also ADHD. Methods: A total of 1,090 children attending grades 1 to 6 in one primary school completed a visual symptom checklist. Their parents also completed a checklist of ADHD symptoms. One hundred eighty eight children were visually symptomatic. Of these, 123 were eligible for clinical testing and agreed to participate in the study and subsequently received comprehensive eye/vision examinations. Thirty one of the children exhibited CI and some of these (N=13) also exhibited ADHD. A therapy group (N=15) underwent a 12-week therapy program and was then compared to a control group (N=16). Pearson correlations were calculated to assess if visual symptoms and/or ADHD symptoms were related to academic scores in reading or mathematics. Odds ratios were calculated to determine the prevalence of symptomatic CI subjects and children with ADHD symptoms, when compared to non-symptomatic children. Results: Visual symptoms and ADHD symptoms were negatively correlated with academic scores for both reading and mathematics. Children with ADHD symptoms were 9-times more likely to have visual symptoms than children without ADHD symptoms. Likewise, ADHD children were 30-times more likely to have CI than children without ADHD symptoms. Visual and ADHD symptom scores, and objective visual measures were statistically improved after 12 weeks of therapy. Conclusion: ADHD and CI are correlated. Further, VT improved visual symptoms, ADHD symptoms and clinical signs of CI in those children with CI and ADHD. Both visual symptoms and ADHD symptoms negatively affected school achievement.

PO-0944 Effectiveness Of Dialectical Behaviour Therapy For Children Suffering From Emotional And Behavioural Disorders

Background and objective One of evidence-based therapies, improving emotional and behavioural problems is dialectical behaviour therapy. This study evaluates the effectiveness of dialectical behaviour therapy for children 8–11 years old. Material and methods The study was carried on 52 children having emotional and behavioural problems and prone to disobey rules or commit crimes. 59.6 percent of the sample were boys and 40.4 percent - girls. The age average of participants is 9.5 ± 0.2 years. Changes in participant’s behaviour were evaluated by means of Lithuanian translation of Achenbach System of Empirically Based Assessment (ASEBA) questionnaire. Results The major effect of dialectical behaviour program was observed when the child had social problems or when his (her) behaviour was aggressive. All participants improved in four aspects: became less aggressive, less prone to break rules, became more attentive and having less social problems. Symptoms of avoidance/depression decreased only for boys, anxiety/depression decreased only for girls. The level of anxiety/depression changed only for ten-year-olds, levels of avoidance/depression and somatic complaints statistically significantly did not change for all age groups. Conclusions This program positively affected the expression of behavioural and emotional problems for children 8–11 years old. The major change was observed in aggressive behaviour, social and attention problems. A tendency for elder children to respond better to the treatment was noticed.

Effectiveness of tnf inhibitors therapy in children with juvenile idiopathic arthritis aged 2 to 5 years

Juvenile idiopathic arthritis (JIA) therapy in the youngest patients (pts) is particularly difficult. Etanercept (ETA) and adalimumab (ADA) are approved for use in moderate and severe JIA in pts older than 2 years, but available data about treatment in the youngest children are limited.

G428(P) Markers of endothelial dysfunction in newborn babies from the group of high perinatal risk

AimsTo determine the role of membrane protein, thrombomodulin, in the prediction of endothelial dysfunction in newborn babies from the group of high perinatal risk.Methods39 children from the group of a...

Effectiveness of Neurofeedback Therapy in Children with Separation Anxiety Disorder

Background: Anxiety disorders are one of the most common psychiatric disorders in children. Its incidence is 2-5% of children and adolescents under age 18. Anxiety disorders are more common in girls than boys. It may start in pre-school, but mostly are in age of 7 to 8 years old. Method: The main objective of this article was to find out the effect of neurofeedback therapy in children with separation-anxiety disorder. Study population was Children from 7 to 12 years old with separation anxiety disorder who were referred to the child psychiatric clinic and they were divided randomly into two groups of 12. One group (N=12) received neurofeedback therapy and the other group (N=12) received sham neurofeedback therapy (placebo). Data was analyzed with t- test by 21th version SPSS software.