Large-scale energy storage is a key enabling technology for the widespread adoption of renewable energy such as wind and solar power. Among various technologies, zinc-based flow batteries stand out as one of the most promising candidates due to the high energy density, low cost, and use of earth-abundant active materials. However, the low operating current density and short cycle life resulting from notorious zinc dendrite formation, large internal resistance, and sluggish reaction kinetics pose a great challenge for their practical applications. Although great efforts have been made to address these issues, previous works mainly focused on one specific aspect, making it challenging to boost the overall performance of zinc-based flow batteries. In this presentation, a systematic study on the effects of key components on the electrochemical performance of zinc-bromine flow batteries will be presented. Our results show that all key components (electrodes, electrolytes, membranes, and flow fields) can exert a significant influence on the electrochemical performance. More impressively, a high areal capacity of >200 mAh/cm2 and an operating current density of as high as 400 mA/cm2 can be achieved by optimizing the design and operating parameters. Underlying mechanisms and perspectives for further improvement will be discussed during the presentation.