Comprehensive Effect Research Articles

Synthesis of P(AM/AA/SSS/DMAAC-16) and Studying Its Performance as a Fracturing Thickener in Oilfields

In order to solve the problems of long dissolution and preparation time, cumbersome preparation, and easy moisture absorption and deterioration during storage or transportation, acrylamide (AM), acrylic acid (AA), sodium p-styrene sulfonate (SSS), and cetyl dimethylallyl ammonium chloride (DMAAC-16) were selected as raw materials, and the emulsion thickener P(AM/AA/SSS), which can be instantly dissolved in water and rapidly thickened, was prepared by the reversed-phase emulsion polymerization method. DMAAC-16, the influence of emulsifier dosage, oil–water ratio, monomer molar ratio, monomer dosage, aqueous pH, initiator dosage, reaction temperature, reaction time, and other factors on the experiment was explored by a single-factor experiment, and the optimal process was determined as follows: the oil–water volume ratio was 0.4, the emulsifier dosage was 7% of the oil phase mass, the initiator dosage was 0.03% of the total mass of the reaction system, the reaction time was 4 h, the reaction temperature was 50 °C, the aqueous pH was 6.5, and the monomer dosage was 30% of the total mass of the reaction system (monomeric molar ratio n(AM):n(AA):n(SSS):n(DMAAC-16) = 79.2:20:0.5:0.3). X-ray diffraction analysis (XRD), infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and scanning electron microscopy analysis were carried out on the polymerization products. At the same time, a series of performance test experiments such as thickening performance, temperature and shear resistance, salt resistance, sand suspension performance, core damage performance, and fracturing fluid flowback fluid reuse were carried out to evaluate the comprehensive effect and efficiency of the synthetic products, and the results show that the P(AM/AA/SSS/DMAAC-16) polymer had excellent solubility and excellent properties such as temperature and shear resistance.

Relative forces of anthropogenic and natural factors on the evolution of "ecological cancer"-rocky desertification under different man-land relationships.

Rocky desertification (RD) is a severe phenomenon in karst areas, often referred to as "ecological cancer." However, studies on RD rarely include comparative analysis of different man-land relationship areas. This lack of analysis leads to difficulties in preventing and controlling RD in local areas with complex man-land relationships. To address this issue, we selected two typical karst areas, Guangnan County (with subtropical humid and agricultural peak-valley area) and Yulong County (with temperate semi-arid and ecological tourism alpine-canyon area), as comparative research areas. We analyzed the evolution of RD in these two typical areas and revealed the relative forces of anthropogenic and natural factors on RD at both a single and comprehensive level by using the geographical detector and the coupled principal component-structural equation model. The study found that (1) the RD in Yulong County was more severe than that in Guangnan County. From 2010 to 2020, RD in both counties showed a positive succession trends. The RD has a high degree of spatial fragmentation, and spatial evolution usually occurs in areas where the man-land relationship is complex. (2) In terms of single factor, the RD in the two counties was mainly affected by anthropogenic factors such as control, farming, behavioral disturbance, and social economy, and natural factors such as geology, soil, topography, and surface state. (3) Comprehensive effects show that forces of anthropogenic vs natural factors on formation/evolution of RD are different between Guangnan County (0.36 for anthropogenic factor vs -0.64 for natural factor) and Yulong County (higher with anthropogenic: 0.44 vs natural: 0.89). (4) Differentiated strategies should be adopted due to role played by anthropogenic and natural factors across different man-land relationship areas to explore suitable control measures for RD. The research creates a scientific basis for the control of RD, ecological restoration, and sustainable development in various regions. It can also be utilized as a valuable reference for comparative analysis of similar geographical phenomena.

Current Insights into Various In Vitro Dihaploidization Techniques Used in Brassica Oil Crops

Brassicas are considered the third most important source of vegetable oil globally. With the escalating production of Brassica varieties, there is growing demand for high-yielding genotypes. Doubled haploid (DH) techniques have become very popular in various Brassica breeding programs. Such DH techniques can play a significant role in plant breeding by accelerating the production of homozygous lines and increasing selection efficiency. Among these methods, isolated microspore culture stands out as the most effective, facilitating the generation of a higher number of embryos compared to conventional methods of plant breeding. Different chemical compounds such as herbicides, brassinosteroids, and polyethylene glycol have an antimitotic effect and have been found to generate DH plants and improve microspore embryogenesis in Brassica species. Colchicine and trifluralin have proven to be efficient chromosome-doubling agents as well as important supplements that can increase the rate of embryogenesis. This review serves as a comprehensive summary and effectiveness evaluation of the latest research findings in the Brassica oil crops to help increase efficiency of the future research focusing on DH methods and application of antimitotic agents in the various oilseed species of the genus Brassica.

Effects of Topography on Vegetation Coverage Changes in Rural Areas Under Multi-scale Scenarios

Revealing the characteristics of vegetation coverage change and the effects of topography on vegetation coverage change in rural areas since the reform and opening up has direct implications for further understanding of human-land coupling processes and resource and environmental changes and provides a reference for ecological environment protection in rural revitalization. Using the Taihua Town in Yixing City, Jiangsu Province, as a rural case study, we revealed the basic features of rural vegetation coverage change from 1986 to 2020. Furthermore, using 0.25 km2（scenario 1）, 0.50 km2（scenario 2）, and 1.00 km2 （scenario 3） as scale scenarios in the study area, both the single and comprehensive topographic effects on vegetation coverage change were explored. The study produced several important results： ① Vegetation coverage in the study area generally maintained an upward trend from 1986 to 2020, during which the spatial pattern of vegetation coverage distribution was generally high in the southeast and southwest and low in the north （northwest）. During this period, the vegetation coverage in the study area increased from 74.15% to 83.44%, and the spatial pattern of vegetation coverage distribution generally remained similar. ② Under the multi-scale scenarios, the vegetation coverage distribution in the study area generally maintained a similar spatial pattern from 1986 to 2020, excepting a few local differences. Under the same-scale scenario, Moran's index of vegetation coverage in the study area was higher in 2020 than in 1986. Taking scenario 1 as an example, Moran's index of vegetation coverage in the study area increased from 0.603 to 0.652 between 1986 and 2020. ③ Under the multi-scale scenarios, from 1986 to 2020, vegetation coverage in the study area generally maintained an upward trend with increase of elevation, slope, and topographic relief. As an example of the vegetation coverage change with elevation, in scenario 1 in 2020, the vegetation coverage in the study area increased from 64.50% in the area with elevations of 0-50 m to 98.77% in the area with elevations above 350 m. ④ Under the multi-scale scenarios, the comprehensive topographic effects on mean vegetation coverage change in the study area from 1986 to 2020 showed that elevation, slope, and topographic relief all had positive effects, and their effects were greater in scenario 3 than in scenario 2 and then in scenario 1 for the same topographic factor. According to the comprehensive topographic effects on mean vegetation coverage change in the study area from 1986 to 2020, the equation simulation coefficients of elevation under scenarios 1, 2, and 3 were 0.271, 0.281, and 0.283, respectively. The respective slope values were 0.283, 0.289, and 0.294, and the topographic relief values were 0.283, 0.292, and 0.295. This suggests that the scale variation has impacts on the comprehensive topographic effects. The results of this study are valuable for understanding the changes in the rural ecological environment under multi-scale scenarios since the reform and opening up.

Greenhouse Gas Emission Characteristics and Influencing Factors from Vegetable Fields with Different Organic Planting Years

To clarify the characteristics of greenhouse gas emissions （CO2, CH4, and N2O） and the comprehensive greenhouse effect from vegetable fields with different organic planting years, the differences in greenhouse gas emission flux, emission intensity （GHGI）, and global warming potential （GWP） and their influencing factors among vegetable fields with different organic planting years in Songhuaba, including 10 years, 6 years, 3 years, and conventional planting, were analyzed. The results showed that the CO2 emissions from organic planting treatments were higher than those from conventional planting, whereas the N2O and CH4 emissions were the opposite. Compared to those from conventional planting, the CO2 emission fluxes and cumulative emissions from organic cultivation for 10, 6, and 3 years increased by 121.28% and 40.44%, 144.61% and 51.39%, and 130.10% and 41.77% （P < 0.05）, respectively, and the N2O emission fluxes and cumulative emissions decreased by 26.08% and 186.03%, 9.6% and 3.55%, and 35.9% and 151.78%, respectively. The CH4 emission flux was shown as follows： conventional planting > organic planting for 10 years > organic planting for 6 years > organic cultivation for 3 years, and the CH4 emissions from cultivational planting and organic planting for 10 years were shown as "source," while the CH4 emissions from organic planting for 6 years and 3 years were shown as "sink." Compared with those from conventional planting, the GWP and GHGI from organic planting for 10 years and 3 years were reduced by 40.57% and 61.43%, 43.83% and 57.98% （P < 0.05）, respectively. Organic planting slightly reduced the vegetable yield but significantly reduced GWP and GHGI （P < 0.05）. Soil temperature and humidity, SOC, and inorganic nitrogen were the key factors affecting the difference in greenhouse gas emissions between treatments. Organic planting significantly reduced greenhouse gas emissions from vegetable fields, and the differences in greenhouse gas emissions among different years of organic planting were closely related to soil organic carbon and inorganic nitrogen. The research results can provide a scientific basis for carbon sequestration, emission reduction, and the green development of organic vegetable production systems.

Elucidating the Underlying Allelopathy Effects of Euphorbia jolkinii on Arundinella hookeri Using Metabolomics Profiling.

Euphorbia jolkinii dominates the subalpine meadows in Shangri-La (Southwest China) owing to its potent allelopathic effects. However, the effects underlying its allelopathy require further characterization at the physiological and molecular levels. In this study, the physiological, biochemical, and metabolic mechanisms underlying E. jolkinii allelopathy were investigated using Arundinella hookeri as a receptor plant. The treatment of A. hookeri seedlings with E. jolkinii aqueous extract (EJAE) disrupted their growth by inhibiting photosynthesis, disrupting oxidation systems, and increasing soluble sugar accumulation and chlorophyll synthesis. Collectively, this causes severe impairment accompanied by abnormal photosynthesis and reduced biomass accumulation. Moreover, EJAE treatment suppressed gibberellin, indoleacetic acid, zeatin, salicylic acid, and jasmonic acid levels while promoting abscisic acid accumulation. Further metabolomic analyses identified numerous differentially abundant metabolites primarily enriched in the α-linolenic, phenylpropanoid, and flavonoid biosynthesis pathways in EJAE-treated A. hookeri seedlings. This study demonstrated that E. jolkinii exhibits potent and comprehensive allelopathic effects on receptor plants, including a significant disruption of endogenous hormone synthesis, the inhibition of photosynthesis, an impairment of membrane and oxidation systems, and changes in crucial metabolic processes associated with α-linolenic, phenylpropanoid, and flavonoid biosynthesis. Thus, our study provides a solid theoretical foundation for understanding the regulatory mechanisms underlying E. jolkinii allelopathy.

Comprehensive TCAD-Based Single Event Effect Study of TFET Based 1T DRAM and Crossbar Memory Array

Comprehensive TCAD-Based Single Event Effect Study of TFET Based 1T DRAM and Crossbar Memory Array

Multifunctional Ru(III)/Fe3O4/DNA nanoplatform for photothermal-enhanced photodynamic and chemodynamic cancer therapy

Among the many cancer treatment methods, there have been many reports on the use of nanoplatforms with single treatment methods such as photothermal, photodynamic or chemodynamic for cancer treatment. In this study, Ru(III) with photodynamic effect and Fe3O4 nanoparticles with photothermal and chemodynamic effects are connected through long DNA chains with efficient active targeting rolling circle amplification to construct Ru(III)/Fe3O4/DNA nano-platform realizes the combination of photothermal, photodynamic and chemodynamic treatment, which significantly improves the therapeutic effect of the nano-platform. Its multiple active targeting capabilities reduce the damage to normal cells. Ru(III) has excellent photodynamic effect and can catalyze the respiration product NADH (Nicotinamide adenine dinucleotide)to produce highly oxidizing H2O2. Fe3O4 NPs has weak absorption at 808 nm indicates that it can perform mild photothermal treatment, and the Fe2+ in it can react with H2O2 to produce ·OH and participate in chemodynamic treatment. Each repeating unit on the rolling circle amplified DNA long chain is connected to the AS1411 aptamer that can actively target cancer cells. Unlike the passive targeting of other nanomedicines, active and efficient targeting is achieved, and a small amount of drugs can achieve high efficacy. The therapeutic effect also reduces the damage to normal cells. The comprehensive killing effect of Ru(III)/Fe3O4/DNA can reach 85.1 %. Its high targeting of cancer cells can also be used for imaging detection of cancer cells. This new nanoplatform provides an idea for the synergy of multiple cancer treatments.

A Retrospective Cohort Study Comparing the Clinical Outcomes of the Hydrosurgery System and Traditional Single-Incision Surgery for Axillary Osmidrosis.

To compare the postoperative scarring, complication rates, and efficacy between the hydrosurgery system and traditional single-incision surgical techniques for treating axillary osmidrosis. A retrospective collection was conducted of all patients who underwent radical surgery for axillary osmidrosis at the Day Surgery Unit of the Department of Plastic Surgery at the First Affiliated Hospital of the Army Medical University from January 2023 to January 2024. Patients were screened based on inclusion and exclusion criteria and divided into the hydrosurgery group and the traditional surgery group. The evaluation was done through medical records, follow-up records, electronic questionnaires, and photographs. Assessments included 6-month postoperative scarring conditions, comprehensive effectiveness scores, postoperative odor/hair/sweating scores, postoperative dermatological life quality scores, and complication rates. A total of 73 patients completed this study: 34 in the hydrosurgery group and 39 in the traditional surgery group. 6 months postoperatively, the hydrosurgery group had significantly lower scores of the Vancouver Scar Scale (VSS), 0.5 (range 0.0-2.0) compared with 1.5 (range 0.5-3.0) in the traditional surgery group (p = 0.018). The incidence of complications such as subcutaneous hematoma, epidermal necrosis, and wound dissidence was also lower (26.5% vs. 51.3%, p = 0.031). Additionally, the surgical incision length in the hydrosurgery group was significantly smaller than in the traditional surgery group (1.200 cm (1.000, 1.275) vs. 2.500 cm (2.500, 3.000), p < 0.001). There were no significant differences between the two groups regarding comprehensive effectiveness scores, postoperative odor/hair/sweating scores, postoperative dermatological life quality index, and surgical duration. Compared with traditional single-incision surgical techniques, patients in the hydrosurgery group exhibited lower scar scores 6 months postsurgery, required smaller surgical incisions, and had lower rates of surgical complications. Thus, the hydrosurgery is suitable for the minimally invasive surgical treatment of axillary osmidrosis, offering a safe, effective, and aesthetically superior treatment method.

Effects of mixed cropping and inoculants on yield and quality of forage under different inter cropping ratios of oat and field pea

Using forage oat and field pea, this study was conducted to explore the effects of sole and mixed cropping patterns at varying ratios, and microbial inoculant application. The aim was to reveal the comprehensive effects of mixed cropping patterns and microbial inoculation on the above-ground biomass, forage yield, and nutritional quality. The results indicated that mixed cropping significantly increased the above-ground biomass of both oats and field peas. With microbial inoculation, mixed cropping increased dry hay yield by 21.81%, 18.31%, 13.33%, and 10.05%; crude protein by 9.4%, 16.44%, 14.98%, and 4.18%, and crude fat by 8.22%, 2.9%, 14.81%, and 5.59% respectively, compared to sole cropping. Additionally, neutral and acid detergent fiber contents decreased by 2.94% and 1.89% on average in mixed crops. These findings suggest that mixed cropping with microbial inoculants can significantly increase forage nutritional quality and yield, offering a scientific basis for efficient forage crop utilization. Bangladesh J. Bot. 53(4): 903-911, 2024 (December)

The effects of expansion and relocation on neighbouring teams in Korean professional baseball league

ABSTRACT Despite the substantial and continually expanding body of empirical literature examining factors influencing attendance demand (Schreyer and Ansari 2022), there is a lack of studies analysing the comprehensive effects of changes in league structure, especially for Asian sports leagues. This study examines how changes in sports league structure, specifically alterations in the number of teams and host cities, affect attendance demand for both new teams and existing teams in Korea baseball league. Our findings reveal several points. Firstly, our analysis affirms the existence of a novelty effect in the inaugural year for newly expanded teams. Secondly, relocated teams face a significant decrease in attendance, persisting over an extended period. Thirdly, the emergence of a new team from either result of expansion or relocation, generally does not affect the attendance of neighbouring teams. Nevertheless, we find evidence of fan substitution when a new team is introduced in a region that previously had only one baseball teams, even in densely populated areas. Conversely, when a region already offers a sufficient number of alternative baseball teams, the introduction of a new team does not significantly impact fan demand. This finding is consistent with current centralized spatial distribution of Korea Baseball Organization franchise.

Higher Tumor/Organ Accumulation Ratio of Porous Dual Infinite Coordination Polymer Nanocomposites for Efficient Tumor Photothermal-Starvation-Dual Hypoxia Chemo Synergistic Therapy.

To enhance tumor comprehensive therapeutic effect of nanomedicines, an efficient strategy that integrates polydopamine and IR780 photothermal therapy, glucose oxidase (GOx) starvation therapy, Banoxantrone (AQ4N) and Tirapazamine (TPZ) dual hypoxia chemotherapy is developed in chronological order. Higher tumor accumulation of porous dual infinite coordination polymer nanocomposites are designed and prepared to implement this strategy, in which fluorescent dye IR780 doped hypoxic prodrugs AQ4N and TPZ coordinated with Cu(II) as the core, this core is encapsulated by GOx-loaded porous polydopamine coordinated with Fe(III) (Fe-MPDA). These nanocomposites exhibit a particle dimension of 118.5±21.7nm with pore size of 20.1nm (pore volume 0.012cm3 g-1nm-1), facilitating easy accumulation in tumor tissues. Particularly, their ratio of the area under the curve (AUC) of the tumor/organ drug concentration versus time (AUCtumor/AUCorgans) is 1.28. Upon reaching the tumor, the nanocomposites release GOx and Fe-MPDA in initial stage to execute photothermal and starvation therapy, simultaneously enhance the hypoxic level at the tumor site. Then AQ4N and TPZ undergo synergistic chemotherapy in the enhanced hypoxic environment. Animal experiments show a tumor inhibition rate of 100% and a tumor recurrence rate of 0% after 60d, demonstrating their great potential application for tumor treatment.

A cell-based exploration of environmental and health impacts of food waste digestate for its sustainable reutilization.

Anaerobic digestion of food waste is increasingly utilized for bioenergy generation, producing a byproduct known as food waste digestate (FWD), which has potential applications as a fertilizer within the circular economy. However, accumulating numerous pollutants in FWD poses significant challenges to environmental management and human health. The complex nature of these pollutants complicates both targeted and non-targeted chemical analyses, making safety evaluations difficult. To address this, we developed a toxicity evaluation protocol based on comprehensive cellular effects to assess the safety profile of FWD. Our study found that human FHC cells were significantly more sensitive to FWD solutions, with 1.2-, 1.8-, and 1.7-fold greater sensitivity than GES-1, HepG2, and HEK293cells. We identified oxidative stress levels and the activation of the NF-κB signaling pathway as crucial and sensitive indicators of FWD-induced toxicity. Metabolomics analysis revealed that FWD triggered the activation of the inflammatory mediator regulation of the transient receptor potential channels pathway, indicating a cellular response aimed at mitigating damage through immune repair mechanisms. By comprehensively assessing these cellular and molecular indicators, we can better predict the potential human and environmental risks associated with FWD. This knowledge is essential for establishing safety guidelines and appropriate dilution ratios for FWD reutilization, enhancing environmental management practices within a circular economy framework.

Effects of Different Remediation Treatments and Rice Intercropping on the Integrated Quality of Paddy Soils Mildly Contaminated by Cadmium and Copper

The issue of soil contamination by heavy metals (HMs) has attracted extensive attention. In the present study, the effects of four remediation measures combined with rice intercropping on the quality of soils were evaluated in a mildly HM-contaminated paddy field. The results showed that better comprehensive remediation effects were found in the intercropping system with high and low Cd-tolerant rice than in the monoculture system. Both foliar spraying of sodium selenite and inoculation with Pseudomonas TCd-1 significantly reduced the Nemerow comprehensive pollution index (NCPI) of the soils. The application of biochar and lime significantly increased the soil fertility index. Among all the treatments, the application of 30 t∙hm−2 biochar and 3600 kg∙hm−2 lime improved soil fertility the most. The lowest single-factor pollution indices (SFPIs) of Cd, Cu, Zn, Ni and Pb and the NCPI of the soils were observed in the treatment with foliar spraying of sodium selenite at 45 mg∙L−1, showing the greatest comprehensive reduction in soil HMs. The application of 1200 kg∙hm−2 lime and 30 t∙hm−2 biochar and foliar spraying of 45 mg∙L−1 sodium selenite effectively improved the soil quality. Overall, the soil quality of paddy fields dramatically influenced the cleaner production of rice and is of great significance to the maintenance of food security.

Research on inclination angle design of container loading and unloading platform based on sliding rail type three-dimensional wharf

At present, the traditional container terminal handling system has many problems, such as high energy consumption, high cost and low efficiency. Therefore, this study drew on the characteristics of "hump" transportation to design a sliding track type, three-dimensional wharf handling system. Meanwhile, considering the design problem of safety dip angle during the loading and unloading operation of the sliding rail terminal, this study constructed the calculation model of the optimal dip angle of the sliding rail operation. This provides a decision support for the improvement of the port handling system. Based on the aforementioned questions, this study first quantified the effects of temperature, humidity and container material. The correction factor for the friction coefficient was obtained. Secondly, combined with the classical mechanics theory, this study developed an optimal calculation model for the inclination of the sliding rail operation under the comprehensive effect of multiple factors. Finally, this study verified the rationality and safety of the optimal dip angle for a specific numerical case of a port. The results show that the safe inclination angle calculated in this case is 21.9°, which meets the requirements of safe operation. The applicability of the above research is verified.

The role of digital marketing in enhancing the sustainability of rural retail businesses in Flagstaff, South Africa

Digital marketing has profoundly altered the marketing techniques utilised by merchants. Although a growing number of rural retail enterprises in South Africa are starting to implement these techniques, the comprehensive effect of digital marketing on their sustainability is still inadequately examined. This study seeks to investigate the impact of internet marketing on retail operations in the rural community of Flagstaff. A quantitative research methodology was utilised, distributing questionnaires to all 52 major merchants via a census technique, yielding 45 replies and an 87% response rate. The results demonstrate that merchants employ several digital marketing strategies, such as social media marketing, email marketing, and mobile marketing, to engage with customers and present sales propositions. This engagement is constrained by the minimal acceptance of digital marketing among consumers, restricted e-commerce utilisation, and inadequate digital literacy, preventing both sides from fully leveraging its advantages. The report advises businesses to persist in using digital marketing methods, including social media and email marketing, into their promotional efforts. This strategy will enable them to engage the niche population that prefers these platforms and maintain alignment with market trends, so assuring competitiveness. Furthermore, it is essential to assist rural areas in improving their digital marketing adoption to sustain retail enterprises and maintain relevance in the contemporary digital environment.

Straw Return with Biodegradable Film Mulch: A Synergistic Cultivation Measure with Environmental and Economic Benefits Based on Life Cycle Assessment

Straw return and plastic film mulching are two critical management measures that not only maintain high and stable crop yields, but also have a significant impact on the ecological environment. However, there is still a lack of research on the comprehensive effects of straw return and different film mulching treatments on the ecological environment. Thus, a 2-year field experiment was conducted and six treatments, which included two main treatments, namely straw return (SR) and non-straw return (NR), and three sub-treatments, namely no film mulching (CK), plastic film mulching (PM) and fully biodegradable film mulching (BM), were applied in a garlic cropping system. Based on the life cycle assessment method, six endpoint damage categories, resource consumption, global warming potential, environmental acidification, eutrophication, human health, and ecotoxicity, were assessed. Furthermore, we also evaluated the costs and economic benefits of the six treatments and optimized the treatment of used mulch and straw off-farm. The results indicated that the environmental impacts of the six endpoint damages in the garlic cropping system were ranked as ecotoxicity, eutrophication, environmental acidification, global warming potential, human health, and resource consumption. The SR-BM treatment had the lowest life cycle environmental impact composite index at 27.68 per unit area, followed by SR-PM at 27.75. All six endpoint damage categories for the PM and BM treatments were lower than the CK treatment per t of yield, with the SR-BM treatment being the most economically efficient, yielding at 3691.03 CNY·t−1 and exceeding that of the SR-CK treatment by 7.26%. Fertilizer inputs were the primary contributor to resource consumption, global warming potential, environmental acidification, eutrophication, and ecotoxicity, accounting for about 72.80% of these five environmental impacts. Crop protection significantly affected human health, and garlic mulching helped minimize pesticide use, thereby reducing potential health impacts. Compared to straw incineration and waste mulch power generation, straw power generation and waste mulch recycling granulation offered positive environmental benefits and were more effective offset strategies. In conclusion, straw return with biodegradable mulch is a synergistic cultivation measure that offers both environmental and economic benefits. For straw return with plastic film mulch, environmental impacts can be reduced by waste mulch recycling granulation.

Comprehensive Effects of Creatine Supplementation on Physical Performance, Recovery, and Health Markers Across Diverse Populations

Background:Creatine supplementation is well-established for its ergogenic benefits, enhancing physical strength, endurance, recovery, and fatigue management across diverse populations. Research highlights its role in mitigating exercise-induced muscle damage and improving health markers, including oxidative stress, hydration, and body composition. This review synthesizes current evidence on creatine's comprehensive effects across varied demographics and activity contexts. Methods:This review examined creatine's effects on performance, recovery, and health markers across athletes, older adults, postmenopausal women, and long COVID patients, analyzing strength, endurance, fatigue, body composition, and biochemical metrics with demographic subgroup analyses. Results:Creatine supplementation improved muscle strength, endurance, and fatigue resistance, especially when combined with resistance training. Benefits included enhanced sprint and jump performance, recovery from muscle damage, and better fatigue management. It also increased lean mass and hydration, reduced oxidative stress, supported bone health, and improved quality of life in clinical populations. Conclusion:Creatine supplementation offers broad benefits for performance, recovery, and health, particularly in athletes, older adults, and clinical populations. Its synergy with resistance training and other supplements underscores its versatility. Future studies should focus on personalized protocols to maximize effectiveness and address individual variability.

THE IMPACT OF CONSUMING PROBIOTIC YOGURT «KARPATSKY» ON IMMUNE PROTECTION AGAINST SEASONAL RESPIRATORY VIRAL INFECTIONS

This study investigates the impact of consuming “Karpatsky” yogurt on immune protection against seasonal respiratory viral infections. Given the increasing prevalence of respiratory infections and the growing interest in probiotic-based preventive measures, our research aims to explore the potential benefits of yogurt consumption on immune function. A total of 90 participants, aged 18-65, were recruited and divided into a test group consuming “Karpatsky” yogurt daily for 12 weeks and a control group maintaining their usual diet. The evaluation of results was based on studying the number of upper respiratory tract infections, the duration of each illness episode, the number, and severity of symptoms. During the analysis of the obtained information, a significant reduction in the frequency, duration, and severity of respiratory infection symptoms was established in the test group compared to the control group, indicating a comprehensive positive effect of the yogurt components ("Karpatsky"), including the probiotic component, on immune protection against seasonal upper respiratory tract infections. The obtained data can be used to develop preventive measures aimed at reducing the risk of seasonal respiratory infections through the consumption of fermented probiotic products. The work carried out opens up prospects for further research related to the study of the long-term effects of consuming probiotic products on the immune system and expanding the sample size to confirm the obtained results in other population groups.

Experimental matrix of organizing independent nursing process in a psychiatric hospital

The article presents an experimental experiment on developing an independent nursing process in working with psychiatric patients, including: developing relevant documentation in electronic and paper form; forming an experimental team of nurses for practical testing of the developed matrix of an independent nursing process based on a comprehensive study of the problems of a psychiatric patient; training psychiatric nurses in mastering the developed matrix; testing this methodology in the conditions of the tuberculosis department of a psychiatric hospital; analysis of the effectiveness of the developed methodology of autonomous nursing intervention based on a comprehensive study of the difficulties of individuals of the studied category; implementation of the methodology in the treatment process of the department; monitoring the results of the effectiveness of the latest development of an autonomous nursing process for the analysis of long-term results and improvement. The purpose of this study was to create a new method for a comprehensive analysis of problems and their solutions in patients with mental disorders. Results. The decisive problems of patients with mental disorders were identified. A special team of nurses was formed to implement the experimental study in their work activities. The staff received appropriate training briefings, explained the goals and objectives of the experiment. Implementation of an innovative matrix for organizing independent nursing interventions in the practical activities of mid-level medical personnel of a psychiatric profile. An analysis of the effectiveness of the experimental process was made. Conclusion. The development and implementation of innovative mechanisms for improving the psychiatric nursing process has a productive moment. The proposed matrix has a comprehensive effect on the block of mental, physical and social problems of the patient, which solves a number of pressing issues and increases the productivity of nursing activities in psychiatry. This allows saving human resources, which is important in the age of a catastrophic shortage of medical personnel. Also of great positive significance is the achieved reduction of time and economic costs when working with psychiatric patients, which effectively solves the difficulties they encounter, mainly of a physical and mental nature.