The present study examined the influence of ethnicity on the effectiveness of cognitive behavioral treatment for PTSD in female victims of sexual and nonsexual assault. Ninety-five women with chronic PTSD (60 Caucasian and 35 African American) were randomly assigned to either active cognitive behavioral treatment or wait list control. Active treatment consisted of nine, twice-weekly, individual sessions of prolonged exposure, stress inoculation training, or a combination. Independent evaluations were conducted at pretreatment, posttreatment, and 12-month follow-up. African Americans and Caucasians did not differ in terms of pretreatment psychopathology or general functioning, dropout rates from treatment, or overall treatment efficacy. These results are discussed within the context of the need for future exploration of ethnocultural factors in the treatment of PTSD.