Effective weed management is crucial for achieving optimal crop performance and yield in rice cultivation. While post-emergence herbicides are commonly used to control weed population (WP), their effectiveness can vary based on the dosage and combinations applied. In this respect, an experiment was conducted at the Agronomy Field Laboratory, Bangladesh Agricultural University, Mymensingh, from December 2019 to May 2020 to predict herbicide-resistant weeds and assess the yield of boro (dry season irrigated) rice (cv. BRRI dhan29) in response to post-emergence herbicides. The experiment consisted of five post-emergence herbicides: Fenoxaprop-p-ethyl, Triafamone, Penoxsulam, Bispyribac-sodium, and Carfentrazone-ethyl, and four doses of herbicide: control, half of the recommended dose (RD), RD, and double the RD. Weed dry weight (DW), WP, and inhibition were significantly affected by different doses of herbicides. Ten weed species (WS) belonging to four families infested the experimental plots, with the most dominant being Echinochloa crus-galli, Scirpus mucronatus, and Scirpus articulatus. The lowest WP and DW, as well as the highest weed control efficiency (WCE), were achieved with double the RD of Penoxsulam and Triafamone, showing 91.09% and 90.13% efficiency, respectively, at 30 DAT. The tallest plants, highest number of effective tillers hill-1, highest grain yield, straw yield, biological yield, and harvest index were found with double the RD of Penoxsulam. In contrast double the RD of Triafamone produced the second-highest grain yield. Although double doses of herbicides increased yield, the variation was not significantly greater than the RD. Some weeds, particularly E. crus-galli, S. articulatus, Leersia hexandra, and Digitaria sanguinalis, survived even with double the RD of herbicides. This indicates a potential for herbicide-resistant weeds.