Flooding is a phenomenon that sometimes has devastating effects on human livelihoods. Impact of floods is more pronounced in low-lying areas due to rapid growth in population, poor governance, decaying infrastructure and lack of proper environmental planning and management. Flooding is also exacerbated by climate change and inadequate preparedness. However, flooding in most Nigerian cities is a major environmental challenge that has continued to defy solution as more people are rendered vulnerable to hazards involved. The implications of recent flooding in Nigerian cities include among others; loss of life and properties, spread of diseases, deformed livelihoods, assets and infrastructure. This paper therefore provides an overview of how Nigerian cities have been affected by flood incidences. The paper contends that prevailing effects of climate change, particularly flooding affecting almost everything in cities demands urgent attention in form of environmental and infrastructure planning, effective policy, improved and effective management of ecological fund, enhanced environmental disaster insurance, effective professional practice, enhanced public enlightment programmes, integration of environmental planning and education to curriculum of schools at all levels, capacity building towards adaptation and mitigation of climate change impact. It also argued for the need to reinvent Nigerian cities through good governance towards creating sustainable cities in the country.