The goal of this study was to improve the mechanical and thermal properties of PolyMethyl Meth Acrylate (PMMA) by adding Zirconia nanoparticles in various weight fraction percentages (0, 1, 1.5, 2, 2.5, 3)%. The cast technique was utilized of to prepare the (PMMA/zirconia) nanocomposites. The thermal and mechanical characterized of (PMMA/zirconia) nanocomposites were studied. Increased zirconia percentages in (PMMA/zirconia) nanocomposites lead to increase thermal conductivity (K), glass transition temperature, specific heat capacity (Cp), effusivity, impact strength, hardness, flexural strength, compressive strength and reduced wear rate, enhancing the thermal and mechanical properties of Poly-Methyl Meth Acrylate (PMMA).