The construction of high-rise buildings, both residential and commercial, is increasing. Every structural designer must be aware of the forces such as earthquake and wind effects. Every engineer is challenged to provide stability and strength for loads such as lateral forces (wind and seismic loading). That is why wind loading has become one of the most important issues in high-rise buildings. Lateral loads are crucial for drift; therefore, drift must be considered for high-rise structures. This research work focuses on the effects of various wind loads on high-rise structures with the provision suggested in IS 875(part 3):2015 and for seismic load using IS code 1893(part1):2016. For the study, four irregular plan building is used with G+20 story in seismic zone V and terrain category II with a basic wind speed of 44, 47, 50, and 55 m/s that is analyzed and designed using the structural analysis software tool STAAD Pro. The bending moment, shear forces, story displacements, story shear, and story drift are analyzed on every level of height on the building, and the results are compared with them.