Article1 September 1942VITAMIN B THERAPY IN PARALYSIS AGITANSWINIFRED C. LOUGHLIN, M.D., H. ARNOLD MYERSBURG, M.D., HERMAN WORTIS, M.D.WINIFRED C. LOUGHLIN, M.D.Search for more papers by this author, H. ARNOLD MYERSBURG, M.D.Search for more papers by this author, HERMAN WORTIS, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-17-3-423 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe numerous therapeutic approaches to the problem of paralysis agitans indicate clearly the inherent difficulties in this problem. It is, therefore, only natural that several investigators have recently turned to vitamin therapy in the hope of finding a more effective weapon for attacking this apparently incurable disease.It is noteworthy that of the six cases reported by Parkinson in his original essay on the shaking palsy one patient attributed his symptoms to over-indulgence in alcohol and another to a long period of neglect in a Spanish prison.1Furthermore, Kikuchi states that monkeys with experimental B-avitaminosis develop mask-like facies, propulsory movements...Bibliography1. PARKINSON J: An essay on the shaking palsy, 1817, Sherwood, Neely and Jones, London. Google Scholar2. KIKUCHI T: Ueber die Avitaminose bei Affen, Japanese Jr. Med. Sci. Trans., 1927, viii, 265. Google Scholar3. LEWYSPIESARING FHTDCD: The incidence of neuropathy in pellagra, Am. Jr. Med. Sci., 1940, cic, 840. Google Scholar4. JOLLIFFE N: The clinical aspects of vitamin B deficiencies, Minnesota Med., 1940, xxiii, 542. Google Scholar5. JOLLIFFE N: Effects of vitamin B6 in paralysis agitans, Trans. Am. Neurol. Assoc., 1940, lx, 54-59. Google Scholar6. SPIESHIGHTOWERHUBBARD TDDPLH: Some recent advances in vitamin therapy, Jr. Am. Med. Assoc., 1940, cxv, 292. CrossrefGoogle Scholar7. JOLLIFFE N: Further results of vitamin B6 therapy in paralysis agitans, presented before the Section of Neurology and Psychiatry, New York Acad. Med., December 10, 1940. Google Scholar8. BEAN WB: Personal communication to the author. Google Scholar9. SPIES TD: The vitamin B deficiencies, Trans. and Stud. Coll. Phys. Philadelphia, 1940, viii, 12. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: New York, N. Y.*Received for publication August 8, 1941.From the Neuropsychiatric Service of the Third (New York University) Division of the Welfare Hospital, New York City, and the Department of Psychiatry, New York University College of Medicine. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byNutritional Aspects of Pyrldoxal as a Coenzyme 1 September 1942Volume 17, Issue 3Page: 423-426KeywordsAlcoholsHospital medicineParalysisParkinson disease ePublished: 1 December 2008 Issue Published: 1 September 1942 PDF downloadLoading ...