The complex deformation behavior would result in surface roughening such as orange peel defect during the hydroforming process of aluminum alloy tubular parts. In order to control the surface quality of hydroformed tubular parts, the effect of strain state on the surface roughening for 2219 aluminum alloy tube was analyzed based on a cross-scale model. The model combined the crystal plasticity model and macroscopic finite element model. During the uniaxial tension, the surface morphology reveals an equiaxed pattern characteristic of orange peel due to the strain incompatibilities between grains, and the peak and valley are stretched along the tensile direction. The surface roughness under tension-compression plane strain state is the lowest due to the low through-thickness strain. In the biaxial tension region, the change rate of surface roughness gradually increases with the decrease of the second principal strain especially in the late deformation stage, and the surface features evolve from an orange peel pattern to a ridging pattern. The forming limit diagram under different strain states based on surface roughness was established to guide the optimization of hydroforming process. Compared with the one-step hydroforming, the surface roughness of the bulging peak of 2219 aluminum alloy tube using multi-step hydroforming with the axial self-feeding decreases obviously from 16.3 to 10.8 μm due to the significant reduction of the equivalent strain.