This exploration addresses the comportments of homogeneous-heterogeneous reactions on peristalsis transportation mechanism of Rabinowitsch fluid model inside a flexible channel. Mathematical modelling and analysis are performed for temperature, velocity and concentration distributions to explore the bearing of influential parameters for Rabinowitsch fluid model (lubricant blended with viscosity index improver) with the dynamic damping and stiffness characteristics. The scope of the current article is valuable in explaining the blood flow dynamics in vessels while considering the essential wall characteristics and chemical reaction. The effects of magnetic field, chemical reaction and velocity slip in blood vessels wall can be described by the presented model. The partial differential equations are formulated by the use of lubrication approach. The expressions for Nusselt number and coefficient of skin friction at the flexible wall are found and evaluated. The effects of homogeneous and heterogeneous reaction parameters shows reverse comportment on concentration field. Moreover, augmentation in skin friction is notice by escalating the parametric values of rigidity and damping.