Prediction of solute distributions in an asymmetric compound channel is carried out using two turbulence models. Results of the numerical models are compared with turbulence data recently obtained using laser Doppler anemometer (LDA) and laser induced fluorescence (LIF) in a small laboratory flume. The predicted distributions of solute and Reynolds flux using a k-s model and an algebraic stress model for various injection points near the water surface are used to identify different mixing mechanisms. A skewed distribution of solute on the floodplain observed in the experimental data is well predicted by the algebraic stress model but not by the k-ε model. The cause of the skewed distribution is examined through the variations of secondary flow and eddy diffusivity. The predicted eddy viscosity and diffusivity and the turbulent Schmidt number are discussed with the experimental data. As a result, solute concentration distribution can be well predicted by adjusting the turbulent Schmidt number even if the eddy viscosity was not correctly calculated by any particular model. An effect of secondary flow on peak concentration in the shear layer along the channel is also demonstrated.