This article presents a systematic literature review of current issues in patients with cerebral palsy and epilepsy. Epilepsy in children with cerebral palsy is characterized by earlier onset, a low frequency of generalized seizures, as well as the use of several antiepileptic drugs and intractable epilepsy. The combination of cerebral palsy and epilepsy has a negative impact on the prognosis of diseases: increase the risk of motor, cognitive and speech dysfunctions as well as intellectual disability due to the hazard of provocative attacks or the seizure frequency and the index of epileptiform disorders. Also, epilepsy in cerebral palsy may complicate the recovery of patients and leads to an aggravation of the epileptic process, being one of the factors of resistance to antiepileptic drugs. Cerebral palsy and epilepsy, as a common causes of childhood disability, have negative social consequences, reducing the quality of life of patients and their families. In order to determine the risk of epilepsy debut in children with cerebral palsy at early ages is important for optimizing its management. Thus, in children with cerebral palsy, a wide range of epilepsy forms are observed: such as severe forms at early onset with mental retardation, frequent attacks (West syndrome), as well as benign forms with later onset, rare attacks with no impact on intelligence. There is currently insufficient data about the prevalence of epileptic syndrome in patients with cerebral palsy, factors contributing to its increase, seizures onset age, the effect of cerebral palsy on the manifestation of epilepsy, the prognosis and optimal treatment approaches. This review indicates the relevance of studying epilepsy in patients with cerebral palsy and require further researches.