Effects of stimulus probability and prediction outcome on two-choice reaction speed (CRS) were determined when a frequency imbalance was reversed half-way through 300 samples of a 70/30 stimulus distribution and when the same 70/30 distribution was sampled for 1200 trials. Prior to each presentation Ss made a prediction; following each presentation Ss identified the stimulus by pressing a right-hand or left-hand trigger. CRS was faster to correctly predicted stimuli, and faster to the more probable stimulus. Ss who were informed of the frequency imbalance reacted significantly faster than Ss who were not. Both practice and boredom effects were demonstrated by using the extended number of trials. CRS was faster during the second session of 300 trials than during the first; after two sessions, CRS was slower during the second half of two additional sessions.