Effect Of Aloe Vera Research Articles

Initial characterization of the effects of Aloe vera at a crayfish neuromuscular junction.

This study examines the effects of Aloe vera on neurotransmission processes in a well-established invertebrate neuromuscular junction preparation. We studied concentration-response relationships of an Aloe vera extract on excitatory junctional potentials (EJPs) at the opener muscle of the dactyl in the first and second walking limbs of crayfish (Procambarus clarkii and simulans). We observed concentration-dependent depolarizations of the muscle fibre membrane resting potential, depression of EJP amplitudes and an increase in latency to onset of the EJP following electrical stimulation of the isolated excitatory axon in the meropodite. These effects occurred with Aloe concentrations within the 1%-10% (wt-vol) range. Effects of lower concentrations, ranging to a minimum of 0.01% were equivocal. The effects of Aloe were at least partially, and in a majority of cases totally, reversible. EJPs reduced by Aloe could be restored by increasing the nerve stimulation amplitude. This, along with the latency increase, suggests a depression of action potential generation and conduction. The results provide a preliminary characterization of the effects of Aloe vera on the neurotransmission process and suggest that these effects may at least partially account for Aloe's analgesic and antiinflammatory effects. This study shows that the crayfish NMJ preparation should be useful for further elucidating the location(s) and mechanism(s) of action of Aloe on the nervous system.

Effects ofAloe vera ingestion in the rat. I. Growth, food and fluid intake and serum chemistry

This study was designed to examine the effects of long-term (1.5 and 5.5 months) Aloe vera (Aloe barbadensis) ingestion on the growth, food intake and serum chemistry of Fischer 344 male rats. Aloe vera powders, produced by two different methods, were mixed with rat chow at selected concentrations. Process A aloe was prepared from skinned aloe filets by homogenization followed by lyophilization and grinding to a fine powder; Process B aloe was prepared similarly except that the homogenate was charcoal filtered prior to lyophilization. Ingestion of Process A aloe at concentrations greater than 1% was associated with diarrhoea and a decrease in weight gain. Ingestion of 1% Process A and both 1% and 10% Process B aloe had no adverse effect on body weight gain, food intake, gastrointestinal transit time and gross pathology. Serum chemistry was minimally affected. The rats ingesting 10% Process B aloe exhibited a slight, but significant increase in fluid intake. The results indicate that, although high concentrations of aloe should be avoided, ingestion of moderate levels (1%) of aloe from either process causes no apparent adverse effects in the rat. © 1998 John Wiley & Sons, Ltd.

Efektivitas Lidah Buaya (Aloe Vera) Dan Daunsirih (Piper Betle Linn) Terhadap Kesembuhan Luka Bakar Derajat Ii Pada Tikus Putih (Rattus Norvegicus Strain Wistar) Di Peternakan Tikus Sidomulyo Kediri

Background: Second grade burn injuryis burns which includes the destruction of epidermis and upper layers of the dermis and injury in the deeper dermis. Smear use aloe vera and betel leafs, it is an non-pharmacological methods that can accelerate the burn injury healing. Objectives: Determine the effectiveness of aloe vera and betel leafs to the healing of grade II burn injury on white rat in Kediri Sidomulyo livestock. Methods: This research uses a True Experimental, with post test only control group design. The sample in this study were 18 male rats, selected using Sample Random Sampling. Theburns injury made by inducing an iron plate (1x1 cm2) that already heated with boiling water for 5 minutes then stick it on the backs of rat for 30 seconds (area of ​​the epidermis). Data collected using observation sheet, ofusing burn injury woundcare observational sheet. Results: Using ANOVA The results of this study showed that the p value = 0.000, which means that H1 is accepted. Conclusions and Suggestion: There are differences in healing burns secondgrade by using a smear of betel leaf and aloe vera on white rats. This study can be recommended as the development of science in medical-surgical nursing for wound care is more effective and faster in accelerating the healing of burn injury.;Key Words :Grade II Of Burn Injury, Aloe Vera, Betel Leafs, White Rats