Acceleration Effect Research Articles

Enantioselective Synthesis of Spiro[cyclopentane-1,3'-oxindole] Scaffolds with Five Consecutive Stereocenters.

A highly diastereo- and enantioselective cascade annulation reaction of Morita-Baylis-Hillman (MBH) maleimides of isatins with ortho-hydroxychalcones was achieved by a chiral N,N'-dioxide/Mg(II) complex Lewis acid catalyst. This strategy provides a concise and efficient route to densely functionalized spiro[cyclopentane-1,3'-oxindole] compounds with five consecutive stereocenters. The reaction itself features mild conditions, good functional group compatibility, and broad substrate scope (62 examples, up to 99% yield, up to >20:1 dr, 97% ee). In addition, an obvious ligand acceleration effect and chiral amplification effect were observed. DFT calculations were performed to elucidate the stereoselectivity observed. The gram-scale synthesis and the inhibitory effect of two products on the viability of A549 cells demonstrate the potential utility of the current method.

Polyamines putrescine and spermidine as modulators of protein aggregation rate: The effect on DTT-induced aggregation of α-lactalbumin

Protein aggregation is undesirable for cells due to its possible toxicity, and is also undesirable in biotechnology and pharmaceuticals. Polyamines are known to be capable of both suppressing and stimulating protein aggregation. In the present work polyamines (spermidine, putrescine) have been shown to alter the pathway of α-lactalbumin aggregation induced by dithiothreitol, leading to the formation of larger protein particles during the initial stages of aggregation and promoting the later stage of sticking of aggregates. According to the aggregation kinetics data, polyamines accelerate protein aggregation in a concentration-dependent manner, with a maximum at 50 mM spermidine and 100 mM putrescine. With a further increase in polyamines concentration the effect of aggregation acceleration decreased, thus, the modulation of the aggregation rate by polyamines was shown. A comparison of the aggregation kinetics and hydrodynamic radii growth data registered by dynamic light scattering with the data obtained by asymmetric flow field-flow fractionation and analytical ultracentrifugation allowed us to describe the early stages of aggregation and formation of initial α-lactalbumin clusters. Our results provide a deeper insight into the mechanism of amorphous aggregation of α-lactalbumin and polyamines action on protein aggregation and protein-protein interaction in general.

Coupled finite element analysis of the dynamics of poroelastic media considering the relative fluid acceleration

AbstractThis paper mainly discusses the dynamics of poroelastic media using the finite element analysis based on the u‐v‐p full formulation, where , , and p denote the solid displacement, relative fluid velocity with respect to solid velocity, and pore fluid pressure. It incorporates the effect of relative fluid acceleration with respect to solid acceleration on soil dynamic response. The ‐‐p formulation is first verified through the comparison with the analytical solution. After that, the response of one‐dimensional saturated soil column and two‐dimensional partially saturated soil layer subjected to vertical loading with different combinations of soil permeability and loading frequency are investigated using the analyses with the ‐‐p and ‐p formulations, based on which the effect of relative pore fluid motion is discussed and the differences in the soil response between two kinds of analysis approaches are examined. Results reveal that the rapid fluid flow has a pronounced effect on soil dynamics and the soil with a greater degree of saturation is more sensitive to the increase of loading frequency and soil permeability. The soil dynamic response can basically be divided into two main categories that represent insignificant and significant flow motion depending on loading frequency and soil permeability. Furthermore, despite vertical loading, horizontal soil response can also be affected by the large relative pore fluid flow when loading frequency and soil permeability are large. In addition, the simplified formulation can still be applicable to predict dynamics of poroelastic media in cases with high loading frequency and low soil permeability.

Synchronous control method for the walking system of the dual forging manipulators based on triangular velocity planning

The primary function of the dual forging manipulators’ walking system is to precisely control the axial feeding of forgings. The stability and control accuracy of this system significantly impact forging quality and production efficiency. To achieve synchronized position control, a mathematical model was developed using two 20 kN forging manipulators as the research subjects. Subsequently, a triangular velocity trajectory planner was devised to examine the effects of acceleration, start–stop coefficient, and peak coefficient on the control behavior of the system. Lastly, the efficacy of this control method, which employing triangular velocity planning (TVP) for displacement–velocity composite control, was confirmed through equivalent experiments. The results indicate that this method can effectively regulate the response dynamics of two walking systems, with a displacement difference of less than 1 mm between the two manipulators.

Flow Development Over An SD7003 Airfoil At Different Accelerations From Rest

This work examines the effect of acceleration on the formation of a laminar separation bubble (LSB). The experiments were performed in a water towing tank with an SD7003 airfoil model accelerated from rest to a constant chord Reynolds number. Quantitative flow field measurements were performed using two-component time-resolved Particle Image Velocimetry (PIV) over a range of accelerations. A detailed analysis of the spatio-temporal flow development is conducted focusing on the LSB formation and dynamics. The results provide insight into the mechanism of LSB formation. The associated transient flow development is shown to persist over several convective time units after steady state free-stream velocity is reached, with no significant effect of acceleration on the overall transient duration. However, the acceleration rate has a substantial effect on flow development during the acceleration phase.

Lattice Boltzmann study of the effect of metal foam on bubble behavior and heat transfer performance in flow boiling

Metal foams with high porosity, light weight, and large specific surface area can significantly enhance heat transfer performance. In this study, the lattice Boltzmann method coupled with the finite difference method is used to investigate the flow boiling characteristics of metal foam surface. Focus is given on the effects of Reynolds number, gravitational acceleration, wall superheat, and metal foam thickness on heat transfer performance. Studies show that increasing the Reynolds number enhances convective heat transfer on the metal foam surface but inhibits bubble nucleation. Compared with a smooth surface, the metal foam takes full advantage of the fluid shear force induced by the high-velocity fluid in the channel-center region, thereby reducing the dependence on buoyancy for bubble detachment. As the wall superheat and metal foam thickness increase, the wake effect induced by bubble detachment is enhanced. Subsequently, bubble detachment is facilitated and the liquid supply is enhanced. These results provide theoretical and applied technical guidance for the structural design of novel metal foam surfaces.

Key influence factors in magneto-controlled motion of micro-nano graphite flakes

Magneto-controlling micro-nano materials’ motion is a promising way that enable the noncontact, remote, and nondestructive controlling of their macrostructure as well as functionalities. Here, an optical microscope with an electromagnet was constructed to in-situ monitor the magneto-controlled motion process microscopically. Taking micro-nano graphite flake (MGF) as a model system, we experimentally demonstrate the key factors that influence the magneto-controlling of materials’ motion. First, the product of intensity and gradient of the magnetic field (B∇B) has been confirmed as the dominant driving force and the flipping direction of the MGFs is accordingly determined by the vector direction of B×∇B. Second, quantitatively comparative experiments further revealed that the threshold driving force has an exponential relationship with the structural aspect ratio (b/a) of MGFs. Third, the critical magneto-driving force is found as proportional to the viscosity of the solvent. Accordingly, a dynamic model is developed that describes the flip of the diamagnetic flake under external magnetic field excitation considering the shape factor. It is shown experimentally that the model accurately predicts the flip dynamics of the flake under different magnetic field conditions. In addition, we also discovered the delay effect, multiple cycle acceleration effect, and the fatigue effects due to gas adsorption in magneto-controlled MGFs flipping. These findings can be used to achieve magneto-controlling materials’ macrostructure as well as their functionalities.

Study on the Selection of Coil Energization Directions in Multistage Synchronous Induction Coil Launcher

In order to enhance the initial velocity and energy conversion efficiency of multi-stage synchronous induction coil launchers, the direction of coil energization for the drive coils is studied. There are typically two energization methods for multi-stage launching devices: (1) PP (Positive-Positive), where positive current is applied to all drive coils, and (2) PN (Positive-Negative), where currents in opposite directions are alternately applied to the drive coils. A finite element model of a four-stage coil launcher is established in ANSYS2022R2, and the acceleration effects of the armature under different inter-stage distances are analyzed for two energization methods. The study reveals that the PN configuration does not always result in higher armature velocities compared to the PP configuration under different inter-stage distances. The theoretical explanation is provided for the variations in the forces exerted by the previous and next drive coils on the armature during the acceleration process. It is found that the magnitude of the induced current in the previous and next drive coils during the launch process is influenced by the inter-stage distance, which in turn affects the electromagnetic thrust coupled with the armature. Thus, the method of determining the direction of current in the launching device coil is obtained.

Shaking table tests for seismic response of jack-up platform with pile leg-mat foundation on sandy seabed

The pile leg-mat foundation is a novel composite foundation designed for jack-up offshore platforms. The seismic response of such foundations in sandy seabeds is an issue that requires significant attention. In this study, shaking table tests were conducted under various input seismic waves to investigate the dynamic response of a seabed platform system subjected to seismic loads. The effects of the peak ground acceleration (PGA), seismic wave frequency, wave type, pile leg insertion depth, and pile length on the response of the seabed platform system were investigated. The results indicated that as the PGA increased, the acceleration response of the soil and platform model increased, increasing the accumulation of excess pore water pressure and the horizontal displacement of the platform model. The acceleration and horizontal displacement responses of the seismic wave with lower frequencies were higher than those with higher frequencies. The peak acceleration amplification factors under the measured and regular seismic waves showed significant differences, with the dynamic response of regular waves to the platform model being pronounced. Under seismic waves with low PGAs, the horizontal displacement of the platform model decreased with increasing pile leg insertion depth or pile length.

Bridging the digital divide: the impact of technological innovation on income inequality and human interactions

This study seeks to understand the nuanced relationship between technological innovation and income inequality with an emphasis on the broader implications of this interplay on human–technology interactions in diverse socioeconomic settings. Using cross-country panel data from 59 nations (31 developed and 28 developing) from 1995 to 2020, the study employed the common correlated effect mean group (CCEMG) estimator. The robustness of our findings was validated using the augmented mean group (AMG) estimator and the panel causality test. The results indicate that technological innovation, while heralded for its potential to bridge communication and operational gaps, inadvertently exacerbates income disparities, with a pronounced effect in developed economies. Moreover, interactions between technological innovation and variables such as economic growth, globalisation and export trade introduce additional complexities, including both buffering and acceleration effects on the primary relationship. These findings shed light on the double-edged nature of technological advancements, underscoring the need for informed policy-making that harnesses the benefits of innovation while mitigating its unintended socioeconomic consequences. The study sets the stage for domain-specific explorations such as in education, public health and business. It also invites interdisciplinary discourse on the ethical and behavioural dimensions of technology adoption, especially user experiences and societal outcomes.

Equations for efficient cycle-by-cycle computation of fatigue crack retardation and acceleration due to amplitude changes

The paper presents an efficient methodology for computation of the evolution of the fatigue crack retardation and acceleration effects due to crack closure during variable amplitude loading. The presented approach can lead to a very effective tool for estimation of residual fatigue life of engineering structures. Conventionally, consideration of variable-amplitude loading is either computationally too demanding, such as in finite element modelling, or challenging to unify the strip-yield model with another computational code. The simple analytical formulae available in literature are based on residual stress, which does not describe correctly the delayed retardation effect and in some cases it can be non-conservative. This work presents simple analytical equations describing the development of the crack closure based on the results of the strip-yield model for amplitude changes at the load ratio R = 0.1. The parabolic function enables simple computation of the maximum crack closure occurring after an overload without running any simulation. The equations also enable computation of crack closure behaviour following amplitude changes with the consideration of various cyclic material properties reflected in the tuneable ratio between the monotonic and cyclic plastic zone sizes.

Effects of irrigation‐induced surface thermodynamics changes on wind speed in the Heihe River basin, Northwest China

AbstractThe Heihe River Basin, located in Northwest China, serves as a major commodity grain base in China due to its state‐of‐the‐art irrigation system. The rapid increase in soil moisture caused by irrigation can alter the land–atmosphere energy fluxes and regulate regional climate. However, the effects and mechanisms of irrigation on wind speed related to thermodynamics remain unclear. Here, we carried out two 10‐year numerical simulations using the Weather Research and Forecast (WRF) model incorporating a real‐time irrigation scheme. By comparing the simulation differences (including and excluding irrigation), we found that irrigation significantly decreased the daily mean and maximum wind speed at 10 m above ground by 0.30 and 0.55 m·s−1, respectively, in the irrigated area during the growth season. Such surface wind slowdown could be explained by irrigation‐induced surface air cooling and, hence, intensifying atmospheric column stability, weakening turbulent momentum transport, as well as opposite‐to‐prevailing winds vector anomaly caused by increased southward pressure gradient. Meanwhile, we also found wind slowdown mainly occurs below 1100 m while acceleration effect above that level. It was highlighted that the surface wind slowdown effect of irrigation substantially improved the performance of the WRF model. Due to the surface wind slowdown effect of irrigation, the positive bias of daily mean and maximum wind speed simulated by the WRF model was reduced by 15.3% and 27.4%, respectively. Our findings implicate the potential importance of irrigation in improving the performance of climate models as well as in explaining the phenomenon of global stilling.

Microdroplet-accelerated cycloaddition of gaseous phenylacetylene and indoline derivatives to form tricyclic quinolines

Microdroplets have exhibited distinct acceleration effects on many reactions, but most of which involve dissolved reactants within the droplets. Here, we modified a sub-atmospheric pressure electrospray ionization source (SAP-ESI) as a reactor to perform the cycloadditions of gaseous phenylacetylene and indoline derivatives to yield tricyclic quinolines. The reactions were found to proceed rapidly with the assist of charged microdroplets in a nitrogen atmosphere. Real-time and on-site capture of the intermediates and products by mass spectrometry reveals the reaction mechanism at the microdroplet interface, which is somewhat different from the conventional catalytic cycloaddition processes. In particular, the radical cations of dimer phenylacetylenes are first generated in microdroplets and then promote the catalyst-free cycloaddition. This research showcases the new potential of microdroplet chemistry to advance gas-phase reactions.

The Effect of Different Accelerators on the Vulcanization of EPDM Rubber

: EPDM (ethylene propylene diene monomer) is a type of synthetic rubber. The products of rubber have great importance in every part of life. EPDM rubber has high tensile strength, high tension, toughness, and is weather resistant. Therefore, EPDM (ethylene-propylene-diene rubber) is widely used in many fields. The aim of this study is to examine the effect of accelerator type on mechanical properties and vulcanization characteristics of EPDM rubber. We used the accelerators; thiazole, sulfonamides, dithiocarbamate, thiuram, and guanidine groups. The results show that the fastest cure time and the best tensile strength are achieved with dithiocarbamates for EPDM rubber.

Thermodynamic performance and flow structures analysis of supercritical CO2 applied in a regenerative cooling channel mounted with mini-ribs

Supercritical CO2 (SCO2) is regarded as a promising supplementary coolant for traditional regenerative cooling at extremely high flight speed (Ma ≥8) due to its superior heat and mass transfer capability. Using sCO2 as the coolant, mini-ribs is introduced to the rectangular regenerative cooling channel to solve the difficulties in transferring enough heat from near walls to core mainstream at a heat flux of 5 MW/m2 in this paper. With the thermophysical properties near the supercritical point interpolated in the solver, flow structures and heat transfer performance in the cooling channels are obtained using a validated k-ω SST turbulence model. Effects of pitch ratios, channel materials and acceleration and buoyancy effects are also investigated in terms of the local bulk heat transfer coefficients, Fanning friction factors and entropy generation numbers by heat transfer and fluid flow. Overall, the existing of mini-ribs improves the heat transfer coefficient and reduces the entropy number by heat transfer at the cost of the increased fluid friction and the corresponding entropy number. Compared with the smooth channel, the overall enhanced factor can reach 1.73 with an overall thermal performance factor of 1.43 and the maximum wall temperature decreases by 27.57 % in the case of P/e = 10. When the solid channel material has higher thermal conductivity, it leads to a more uniform temperature distribution and lower entropy generation number by heat transfer with the enhanced transverse heat conduction within solid walls which also leads large heat transfer coefficients. Larger accelerations result in stronger heat transfer and larger fluid friction by strengthening the buoyancy effect which is more obvious when the state approach the critical point. This work provides a good reference for the application of supercritical CO2 in a regenerative cooling channel of scramjet engine at extremely high heat flux.

Comprehensive Analysis of Pressure Drop Phenomena in Rotating Packed Bed Distillation: An In-Depth Investigation.

A rotating packed bed (RPB) is an innovative intensification technology that improves its separation capabilities in high-gravity conditions. This process increases efficiency with smaller equipment size and footprint than conventional packed columns. Although significant advancements have been made regarding RPBs, most studies only focused on single or dual rotor configurations in addressing dry pressure drop. Hence, multiple rotor systems in industrial settings can enhance economic efficiency by minimizing the necessity for numerous RPBs. This study investigated the pressure drops and holdup in a three-stage rotor-based RPB under actual process conditions using natural gas as the feed. A novel pressure drop correlation was introduced based on the nitrogen removal process from the natural gas in continuous RPB distillation operations. Consequently, the correlation between centrifugal acceleration, turbulent, and momentum effects demonstrated remarkable accuracy within ±15%. This outcome also highlighted the importance of meticulous design considerations in RPB-based applications due to the complex correlation between centrifugal forces, liquid holdup, and gas flow rates. The reflux feed ratio, liquid holdup, rotating speed, and F-factor effects were examined to comprehend the RPB distillation process. Overall, the correlations between the critical parameters offered crucial insights to prevent process upsets (such as flooding), contributing to advancing RPBs in practical industrial settings.

Artificial intelligence orientation and internationalization speed: A knowledge management perspective

This study explores the role of Artificial Intelligence (AI) orientation in facilitating the internationalization speed of enterprises from emerging economies. Based upon a knowledge management perspective, the paper proposes that AI orientation positively affects internationalization speed via broadening the scope of new knowledge, promoting knowledge creation, application, and dissemination within organizations, and hastening the redundancy of existing knowledge to increase adaptability to global dynamics. Moreover, while online local knowledge search facilitates, offline local knowledge search constrains the acceleration effect of AI orientation on internationalization. Using a dataset from China, the paper finds that AI orientation has a significant positive effect on accelerating the internationalization processes of emerging market firms, and home country embeddedness negatively while regional digital development positively moderates this relationship. The findings contribute to the literature by elucidating how AI orientation expedites the process of an emerging market firm's internationalization from a knowledge management perspective, thereby providing insights for the future scholarly investigation and practical applications in this field.

Low Barriers and Faster Electron/Ion Transport Rates through the Ga2O3/MnCO3 Anode with a Heterojunction Structure for Lithium-Ion Batteries.

Electrode stability can be controlled to a large extent by constructing suitable composite structures, in which the heterojunction structure can affect the transport of electrons and ions through the effect of the interface state, changed band gap width, and the electric field at the interface. As a promising electrode material, the Ga-based material has a conversion between solid and liquid phases in the electrochemical reaction process, which endows it with self-healing properties with the structure and morphology. Based on these, the Ga2O3/MnCO3 composite was successfully synthesized with a heterogeneous structure by introducing a Ga source in the hydrothermal process. Benefitting from the acceleration effect of the internal electric field and the narrower band gap at the interface, a high-capacity Ga2O3/MnCO3 composite electrode (1112 mAh·g-1 after 225 cycles at 0.1 A·g-1 and 457.1 mAh·g-1 after 400 cycles at 1 A·g-1) can be achieved for lithium-ion batteries. The results can provide a reference for the research and preparation of electrode materials with high performance.

Influence of Interaction between Microcracks and Macrocracks on Crack Propagation of Asphalt Concrete.

This paper aims to reveal the interaction relationship between microcracks and macrocracks and the influence of the interaction on the crack propagation behavior. A theoretical model of asphalt concrete was established for the interaction between microcracks with different crack densities and a macrocrack. And a meso-structure model of AC-13 dense-graded asphalt concrete was established by combining the Talyor medium method and the DEM (discrete element method). Macro and micro parameters, such as the stress-strain characteristics, crack evolution parameters, and crack tip stress field, were obtained through a semi-circular bend virtual test and used to study the characteristics of crack propagation under the interaction between microcracks and the macrocrack. The results indicate that the interaction has an effect throughout the process of asphalt concrete damage, and shows shielding and acceleration effects as the microcrack density changes. When the microcrack density is low (f3 ≤ 0.8), the crack propagation process, which is affected by the interaction effect, exhibits significant differences, and the interaction effect shows the shielding effect. When the microcrack density is high (f3 > 0.8), the fracture stage is mainly affected by the interaction effect, which shows the acceleration effect. The results provide a predictive theoretical and numerical model for low-temperature cracking of asphalt pavement, and theoretical support for the design, maintenance, and upkeep of long-life pavement.

Synergistic effect of microorganisms and a direct current electric field on X70 steel corrosion in a near-neutral solution

In this paper, the corrosion behavior of X70 steel in the near-neutral simulated soil solution (NS4 solution) under the synergistic effect of sulfate reducing bacteria (SRB) and a direct current electric field (DCEF) were explored. The corrosion rate was determined with the electrochemical technique and the corrosion morphology and corrosion products were respectively characterized by SEM and XPS. In the sterile solution, corrosion morphology of X70 steel was pitting and the corrosion rate increased with the increase in DCEF intensity and exposure time. When DCEF was absent, the corrosion rate of X70 steel in bacterial NS4 solution was faster than that in the sterile solution and the corrosion morphology was general corrosion. The acceleration effect of DCEF on corrosion was more significant than that of SRB. Under the synergistic effect of SRB and DCEF, when DCEF intensity increased below 500 V/m, the metabolic activity of SRB was gradually enhanced and the corrosion rate of X70 steel decreased. The protective effect of biofilm weakened the acceleration effect of DCEF on corrosion and the corrosion behavior was controlled by SRB corrosion. When DCEF intensity increased above 1000 V/m, SRB cells were inactivated and the corrosion rate of X70 steel increased. The corrosion behavior of X70 steel was controlled by DCEF. Based on the above research results, preventative actions were proposed.