EEG Abnormalities In Patients Research Articles

Hereditary nephritis (Alport syndrome): MR imaging findings in the brain

Previous clinical studies only described epilepsy and EEG abnormalities in patients with hereditary nephritis (Alport syndrome). In this paper, brain MR imaging findings in a 10-month-old boy with hereditary nephritis are described. These included patchy and nodular lesions in the thalami and basal ganglia, and retarded white matter myelination. The findings suggested an intracranial vasculitis or vasculopathy associated with the syndrome.

2-15-07 Quantitative EEG abnormalities in patients with migraine

2-15-07 Quantitative EEG abnormalities in patients with migraine

The relationship between television frame rate and EEG abnormalities in patients with photo and pattern sensitive epilepsy

The relationship between television frame rate and EEG abnormalities in patients with photo and pattern sensitive epilepsy

EEG abnormality in patients with febrile seizures: Cases with the same paroxysmal discharges for more than 3 years

EEG abnormality in patients with febrile seizures: Cases with the same paroxysmal discharges for more than 3 years

Preoperative Cerebrovascular Symptoms and Electroencephalographic Abnormalities Do Not Predict Cerebral Ischemia During Carotid Endarterectomy

The purpose of this prospective study was to establish (1) whether patients with neurological symptoms scheduled for carotid endarterectomy had an increased incidence of electroencephalographic (EEG) abnormalities during awake baseline recordings, (2) whether these symptoms and EEG abnormalities predicted ischemic EEG pattern changes at carotid artery cross-clamp, and (3) whether there was an association between age, presence of EEG baseline abnormalities, and ischemic pattern changes at carotid artery cross-clamp. We reviewed the medical record of each patient scheduled to undergo carotid endarterectomy and recorded the patient's age and history of previous neurological symptoms. We then continuously monitored and analyzed 16 channels of anteroposterior bipolar EEG and two of referential derivations from at least 5 minutes before induction of anesthesia and throughout the operation. We completed 394 consecutive studies. Preoperative neurological symptoms were related to EEG abnormalities in awake patients (P < .001) and to EEG asymmetries in anesthetized patients (P < .001). Abnormal awake EEG findings were associated with asymmetries after anesthesia (P < .0001). Twenty-eight percent of both symptomatic (70/249) and asymptomatic (41/145) patients had EEG ischemic pattern changes at carotid artery cross-clamp. Neither neurological symptoms nor EEG abnormalities were associated with age or the development of EEG ischemic pattern changes at carotid artery cross-clamp. Despite the strong association between a history of cerebral ischemic symptoms and preoperative EEG abnormalities in patients undergoing carotid endarterectomy, patients who have suffered strokes or transient ischemic events are at no greater risk of having EEG evidence of cerebral ischemia during carotid artery cross-clamp than patients without symptoms and with normal baseline EEGs. We conclude that preoperative EEG abnormalities in symptomatic patients are not due to age or to insufficiency of regional cerebral blood flow.

Topographic distribution of the periodic discharges in Creutzfeldt-Jakob disease (CJD)

A characteristic EEG abnormality in patients with Creutzfeldt-Jakob disease (CJD) consists of periodic high voltage bilateral diphasic or triphasic sharp waves widely distributed over both hemispheres. The mechanism underlying these electrographic manifestations is, however, unclear. To increase our understanding of these phenomena, we have employed the technique of microcomputer brain mapping, to analyze the electrical fields of the bilaterally-distributed complexes in four patients with CJD. Ten generalized discharges were studied in each patient. The EEG analysis demonstrated variability in the area of onset as well as the field maxima between the different complexes among patients as well as between discharges in each patient. The generalized pattern seen in routine EEG was clearly shown on brain mapping to be not strictly generalized from onset, nor bilaterally symmetrical. These findings may suggest multifocal areas of onset of the generalized discharges, or alternating pathways of activation of the cortical areas by a subcortical pacemaker.

Changes in EEG mean frequency associated with anxiety and with amphetamine challenge in BPD

Recent authors have hypothesized that cerebral dysfunction, as reflected in an abnormal EEG, may play an important role in the behavioral symptoms of patients with borderline personality disorder (BPD). Spectral analysis and amphetamine challenge testing are two promising methods for probing the clinical symptomatology of this disorder. In this study, we evaluated the relationship between clinical symptoms and computerized EEG spectral analysis in BPD patients both before and after amphetamine challenge. We found that mean frequency values on spectral analysis consistently correlated with anxiety levels in our patients, but did not correlate with a wide variety of other important symptoms, such as depression or transient psychosis. This result, coupled with our previous negative findings concerning EEG abnormalities in patients with BPD, casts doubt on the etiological relationship of cerebral dysrhythmias to the behavioral pathology of this disorder, but raises interesting questions concerning the relationship of anxiety and mean frequency.

Spike EEG abnormalities in patients without epileptic seizures: a clinical and long-term follow-up study.

A study was conducted on a total of 850 patients who had not previously manifested any epileptic seizures but exhibited at least one spike EEG abnormality. They accounted for 7.2% of the total number of patients without epileptic seizures (850/11,773). Among the 850 patients, 564 were followed up for 1-24 years. Nine boys and one girl, i.e. 1.8% of the 564 patients, had manifested epileptic seizures during the observation period. They expressed the following six characteristics: males, first EEG examination at 0-4 years of age, onset of initial chief complaints at 0-6 years of age, mental retardation, spike and wave EEG abnormalities and past history of perinatal birth injuries. These factors are considered to be efficient in detecting patients liable to manifest epileptic seizures later.

脳波の二次元表示とその臨床的応用

脳波の二次元表示とその臨床的応用

Topographic Display of Slow Wave Types of EEG Abnormality in Patients with Brain Lesions

Topographic Display of Slow Wave Types of EEG Abnormality in Patients with Brain Lesions