The results of the analysis of recent studies on the creation of an educational environment in the institution of general secondary education (classification, typology, structural components) has shown the need for its detailed analysis regarding the consideration of personal orientation. To this end, the state of school practice was studied in terms of the organization of educational interaction of education applicants with the objects of the school educational environment. In particular, such aspects as psychological comfort, focus on maintaining health, taking into account the individual psychological and physiological characteristics of students. As demonstrated by the results of scientific research in institutions of general secondary education, the free choice of pupils from different fields of study, with a conscious choice of objects, methods and types of educational interaction not only in accordance with the inclinations and abilities, but also individual psychological and physiological features, is not fully ensured. Particular attention of the designers of the educational environment of the school requires the creation of psychological comfort of students, primarily due to humanization of relations between the participants in the educational process, the strengthening of the ties between school and family, personalization of the school environment, the creation of a favorable training regime and the structure of the school year, taking into account the volume and distribution of the amount of hours, according to the state of health, the initial levels of school readiness, the age range of engagement in the learning of a particular contingent of students, their individual psychological and age characteristics, activity periods at certain times of day, week, month, year, etc., as well as active involvement of students into this activity. It is also important to harmonize the internal and external educational environment, as well as the social, which is formed at school. This is evidenced by the volume of school-based learning material that remains unclaimed in the life of the education applicants. Prospects for further research on effective organization of educational interaction of students with objects of the school educational environment are also outlined. In particular, the process of harmonization of objective and subjective determinants of its effectiveness.