Abstract Background and Aims Kidney disease, including chronic kidney disease (CKD), affects more than 850 million people globally. At least 40% of people with diabetes develop CKD, and many progress to end-stage kidney disease (ESKD) and kidney failure. Globally, diabetes is the leading cause of kidney failure requiring transplantation or dialysis. The risk of both progression to kidney failure and cardiovascular (CV) events is significantly elevated in patients with type 2 diabetes (T2D) and CKD. Both T2D and CKD are CV disease (CVD) risk multipliers. Patients at early stages of CKD are more likely to die of CVD than they are to progress to ESKD. The goal of this online medical education activity was for learners to better acknowledge serious health risks associated with CKD in patients with T2D and have greater awareness of the availability of novel treatment options shown to reduce the risk of associated complications. Method An interactive text-based educational program including two detailed patient cases challenges clinicians to apply most recent evidence-based guideline recommendations. Detailed scenarios prompt learners to determine the correct treatment and follow-up for the patient with expert commentaries providing in-depth advice at each stage and a conclusion at the end of the program. Educational effect was assessed using a repeated-pair design with pre-/post-assessment. 3 multiple choice questions assessed knowledge/competence, 1 question rated on a Likert-type scale assessed confidence. A paired samples t-test was conducted on overall average number of correct responses and for confidence rating, a McNemar's test was conducted at the question level (5% significance level). Cohen's d with correction for paired samples estimated the effect size of the education on number of correct responses. Data collection from 24 February 2023 to 20 April 2023. Results Conclusion Participation of PCP and NEPH in an interactive case-based online medical educational program improved their knowledge, competence and confidence in the management of patients with T2D and CKD.