Metabolic bone disease can present in a variety of ways including anorexia, lethargy and pathological fractures. Radiographs, haematology and biochemistry are useful to determine the extent of the disease to detect any underlying pathology. Treatment will involve both stabilising the reptile and correcting underlying husbandry and dietary factors. Calcium and vitamin D supplementation should be provided and supportive treatment is indicated. Prognosis is variable and will depend on chronicity of the disease, systemic health of the reptile, age and reproductive state. Metabolic bone disease is an avoidable condition and good owner education is vital in preventing its occurrence.