Abstract
Flea allergy dermatitis (FAD) is a progressive form of skin hypersensitivity in dogs and cats caused by exposure to flea saliva through flea bites. This condition represents a source of frustration to pet owners and veterinary practitioners. FAD is associated with a wide spectrum of dermatological manifestations, which can have a dramatic impact on the quality of life of the patient. Significant progress has been made in unravelling the pathogenesis of this disease. Research evidence suggests that both host- and flea-derived factors play a critical role in the pathophysiology of FAD. Despite the availability of effective modern anti-flea chemotherapeutic products, flea infestation and FAD remain a challenging problem. These facts underscore the importance of maintaining sustainable preventive measures, including a rational flea control regimen, judicious use of chemotherapeutic agents and pet owner education.
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