Last month, after 18 years of government service, William Harris abandoned the no-nonsense National Science Foundation for the fringes of science: He took over as director of Biosphere 2. Harris' new boss, University, began managing the controversial megaterrarium, located in the cactusfilled desert of Arizona, early this year. Originally conceived as a sealed laboratory for would-be explorers of Mars, Biosphere 2 fell into scientific disrepute when its eight original residents suffered from a lack of oxygen in their artificial atmosphere (see sidebar). prestigious university hopes not only to establish a sterling research facility at Biosphere 2 but to experiment with the education of environmental scientists and save the planet into the bargain. Columbia is going into this with its eyes wide open, says Harris. The question is whether Biosphere can be converted into a place for real science. Still, the question remains: Why perform vital research at the site that spawned a thousand late-night television jokes? It's a national treasure, says Bruno Marino, a Harvard University researcher who managed the site for much of the last 2 years. Marino took up the reins after Biosphere 2's owner, Texas billionaire Edward P. Bass, banished the original management and decided to make it a facility for environmental science research. Marino, who still operates an experiment at the site, compares it to the Sphinx. Its allure is magnetic. It suggests numerous opportunities for research, but it's a difficult riddle to solve. While the mythological Sphinx tended to kill those who failed to solve the riddle it posed, the only thing Biosphere 2's new management has to lose is its reputation. crew of researchers, educators, and tour guides plans to operate the site as a respected center for environmental science research and education. With a few alterations, they hope this westernmost sprig of the Ivy League will become a center for predicting nature's response to a changing atmosphere. An intriguing arrangement between the university and Bass allows for longlasting improvements to the facility. At the end of the contract, the school will either turn in its keys, extend the management operation, or receive outright ownership, says Bass. For the next 5 years, agrees to manage Biosphere 2 in much the same manner that other universities run federal laboratories. deal reportedly pays $50 million, which it plans to plow back into maintenance and renovations. Simply cooling the greenhouse costs $1 million a year. Columbia University's leadership of Biosphere 2 has already proven to be tremendous, says Bass.