Edge Artifacts Research Articles

The edge artifact extraction method for Si3N4 ceramic bearing rolling element microcracks characterization

Aiming at the problem that the edge artifacts of Si3N4 ceramic bearing rolling element microcracks have low contrast, contain noise, and easily merge with the background, making it difficult to segment. A method based on 2D discrete wavelet transform and Otsu threshold segmentation is designed to achieve the extraction of microcrack edge artifact features. Wavelet decomposition is used to remove noise, while wavelet reconstruction features are used to restore lost details. Creation of 2D discrete wavelet transform functional equations combining wavelet reconstruction and wavelet decomposition to improve contrast and eliminate noise in images featuring edge artifacts. For the problem of feature edge artifacts that are difficult to remove, the threshold segmentation function equation is designed to maximize the interclass variance, and the optimal threshold value is selected to remove the edge artifacts. The experimental results show that the average PSNR of the Si3N4 ceramic bearing rolling body point, line, and surface microcrack edge artifact feature images enhanced by the method in this paper is close to 62.69 dB, and the average SSIM is about 0.77. The method in this paper improves the contrast of microcrack edge artifact features of Si3N4 ceramic bearing rolling bodies and makes the feature extraction effect of point, line, and surface microcrack edge artifacts more complete.

Enhancing Underwater Images through Multi-Frequency Detail Optimization and Adaptive Color Correction

This paper presents a novel underwater image enhancement method addressing the challenges of low contrast, color distortion, and detail loss prevalent in underwater photography. Unlike existing methods that may introduce color bias or blur during enhancement, our approach leverages a two-pronged strategy. First, an Efficient Fusion Edge Detection (EFED) module preserves crucial edge information, ensuring detail clarity even in challenging turbidity and illumination conditions. Second, a Multi-scale Color Parallel Frequency-division Attention (MCPFA) module integrates multi-color space data with edge information. This module dynamically weights features based on their frequency domain positions, prioritizing high-frequency details and areas affected by light attenuation. Our method further incorporates a dual multi-color space structural loss function, optimizing the performance of the network across RGB, Lab, and HSV color spaces. This approach enhances structural alignment and minimizes color distortion, edge artifacts, and detail loss often observed in existing techniques. Comprehensive quantitative and qualitative evaluations using both full-reference and no-reference image quality metrics demonstrate that our proposed method effectively suppresses scattering noise, corrects color deviations, and significantly enhances image details. In terms of objective evaluation metrics, our method achieves the best performance in the test dataset of EUVP with a PSNR of 23.45, SSIM of 0.821, and UIQM of 3.211, indicating that it outperforms state-of-the-art methods in improving image quality.

Optimization of reconstruction in quantitative brain PET images: Benefits from PSF modeling and correction of edge artifacts.

Modern PET reconstruction algorithms incorporate point-spread-function (PSF) correction to mitigate partial volume effect. However, PSF correction can introduce edge artifacts that lead to quantification errors. Consequently, current international guidelines advise against using PSF correction in brain PET reconstruction. We aimed to investigate PSF-induced quantification errors in recent digital PET systems and identify conditions that mitigate them. This study utilized brain PET imaging with alginate-based realistic phantoms, simulating lesion-to-background activity ratios of 10:1 and 2:1, with eleven reconstruction parameter sets. Phantoms were prepared using a commercial anthropomorphic head phantom and two homemade inserts. Each insert contained a homogeneous 18F-FDG alginate background with hot spheres of varying diameter (3, 4, 6, 8, 10, 12, and 15mm). PET imaging was conducted on a digital PET-CT system Biograph Vision 600 (Siemens), with a 10 min scan duration. Imaging was performed with and without PSF correction, with 2, 4, 6, 12, 18, or 24 iterations in reconstruction, and with or without additional Gaussian postfiltering. We assessed the recovery coefficient (RC), contrast recovery coefficient (CRC), variability, and CRC-to-variability ratios for each sphere size and reconstruction parameter set. PSF-corrected images of the 10:1 spheres exhibited a nonmonotonic CRC-to-sphere diameter relationship due to edge artifacts overshoot in the 10mm-diameter sphere. In contrast, PSF images of the 2:1 spheres showed a monotonically increasing relationship. Non-PSF images of both phantoms showed an expected monotonically increasing CRC-to-sphere diameter relationship but with lower CRC values compared to PSF images. The nonmonotonic relationship observed with 10:1 spheres was mitigated by applying a 3-mm FWHM Gaussian postfiltering. For both phantoms, reconstructions with 6 iterations, PSF correction, and additional 3-mm FWHM Gaussian postfiltering demonstrated the highest CRC-to-variability ratios. Our findings indicate that Gaussian postfiltering suppresses PSF artifacts. This parameter set corrected the nonmonotonic CRC-to-sphere diameter relationship and improved the CRC-to-variability ratio compared to non-PSF reconstructions. Therefore, to enhance lesion detectability without compromising quantification accuracy, PSF correction coupled with Gaussian postfiltering should be used in brain PET.

Timing offset calibration for TOF PET using stationary line source scans at multiple positions

Background. Accurate timing offset calibration is crucial for time-of-flight (TOF) positron emission tomography (PET) to mitigate image artifacts and improve quantitative accuracy. However, existing methods are often time-consuming, complex, or costly.Objective. This paper presents a method for TOF PET timing offset calibration that eliminates the need for costly equipment, phantoms, short-half-life sources, and precise source positioning.Approach. We estimate channel timing offsets using stationary scans of a68Ge line source, typically used for routine quality control, at a minimum of three non-coplanar positions, with each position scanned for two minutes. The line source positions are accurately determined by applying a simple algorithm to their reconstructed images, allowing precise calculation of arrival time differences. Channel timing offsets are estimated by solving a least squares problem. This method is assessed through analyses of phantoms and patient images using a RAYSOLUTION DigitMI 930 scanner.Main results. The estimated timing offsets ranged from -500 ps to 500 ps across all channels. Calibration with a minimum of three scanned positions was sufficient to correct these offsets, achieving less than a 1% discrepancy across various metrics of the image quality (IQ) phantom compared to 12 positions. This calibration significantly reduced edge artifacts in TOF reconstruction of both phantoms and patients. Furthermore, the IQ phantom displayed a 14% increase in average contrast recovery, a 61% reduction in average background variability across all spheres, and a 90% reduction in average residual error. Consistent with the phantom results, patient data revealed enhancements in maximum standardized uptake values (SUVmax) from 14% to 55% for lesions measuring 6 mm to 14 mm. The calibration also improved lesion-to-background contrast and eliminated artifacts caused by the spillover effect of the kidneys and bladder.Significance. The proposed method is fast, user-friendly, and cost-effective, effectively improving lesion detection and diagnostic accuracy.

MSSFNet: A Multiscale Spatial-Spectral Fusion Network for Extracting Offshore Floating Raft Aquaculture Areas in Multispectral Remote Sensing Images.

Accurately extracting large-scale offshore floating raft aquaculture (FRA) areas is crucial for supporting scientific planning and precise aquaculture management. While remote sensing technology offers advantages such as wide coverage, rapid imaging, and multispectral capabilities for FRA monitoring, the current methods face challenges in terms of establishing spatial-spectral correlations and extracting multiscale features, thereby limiting their accuracy. To address these issues, we propose an innovative multiscale spatial-spectral fusion network (MSSFNet) designed specifically for extracting offshore FRA areas from multispectral remote sensing imagery. MSSFNet effectively integrates spectral and spatial information through a spatial-spectral feature extraction block (SSFEB), significantly enhancing the accuracy of FRA area identification. Additionally, a multiscale spatial attention block (MSAB) captures contextual information across different scales, improving the ability to detect FRA areas of varying sizes and shapes while minimizing edge artifacts. We created the CHN-YE7-FRA dataset using Sentinel-2 multispectral remote sensing imagery and conducted extensive evaluations. The results showed that MSSFNet achieved impressive metrics: an F1 score of 90.76%, an intersection over union (IoU) of 83.08%, and a kappa coefficient of 89.75%, surpassing those of state-of-the-art methods. The ablation results confirmed that the SSFEB and MSAB modules effectively enhanced the FRA extraction accuracy. Furthermore, the successful practical applications of MSSFNet validated its generalizability and robustness across diverse marine environments. These findings highlight the performance of MSSFNet in both experimental and real-world scenarios, providing reliable, precise FRA area monitoring. This capability provides crucial data for scientific planning and environmental protection purposes in coastal aquaculture zones.

Semantic guidance incremental network for efficiency video super-resolution

AbstractIn video streaming, bandwidth constraints significantly affect client-side video quality. Addressing this, deep neural networks offer a promising avenue for implementing video super-resolution (VSR) at the user end, leveraging advancements in modern hardware, including mobile devices. The principal challenge in VSR is the computational intensity involved in processing temporal/spatial video data. Conventional methods, uniformly processing entire scenes, often result in inefficient resource allocation. This is evident in the over-processing of simpler regions and insufficient attention to complex regions, leading to edge artifacts in merged regions. Our innovative approach employs semantic segmentation and spatial frequency-based categorization to divide each video frame into regions of varying complexity: simple, medium, and complex. These are then processed through an efficient incremental model, optimizing computational resources. A key innovation is the sparse temporal/spatial feature transformation layer, which mitigates edge artifacts and ensures seamless integration of regional features, enhancing the naturalness of the super-resolution outcome. Experimental results demonstrate that our method significantly boosts VSR efficiency while maintaining effectiveness. This marks a notable advancement in streaming video technology, optimizing video quality with reduced computational demands. This approach, featuring semantic segmentation, spatial frequency analysis, and an incremental network structure, represents a substantial improvement over traditional VSR methodologies, addressing the core challenges of efficiency and quality in high-resolution video streaming.

Mobile forensic photogrammetry in the field: Conservative approach to non-collaborative surfaces

Conventional photogrammetry faces challenges with non-textured, transparent, or reflective surfaces, affecting accurate 3D modeling, particularly in forensic documentation. This study evaluates improvements using lower exposure, exposure bracketing, and RAW format for better 3D modeling of non-textured surfaces. Two bodies were photographed under controlled conditions to assess techniques for non-textured surfaces, with a comparison set for textured surfaces. The experiments were conducted in an autopsy room with a Nikon D5500 camera, adjusting for low exposure, exposure bracketing, RAW format, and increased photo redundancy. Models with Meshroom (Alicevision). Our focus was on visual plausibility rather than quantitative metrics. Results indicated that using RAW format with exposure bracketing and low exposure significantly improved 3D models by reducing artificial edges seen with standard JPG images, despite some noise. A redundant series of RAW photos further reduced edge artifacts and noise, demonstrating the effectiveness of averaging photos to enhance model quality. However, these modifications showed marginal improvements on textured surfaces, underscoring their significant benefits primarily for non-textured surfaces. This study highlights the potential of modified photogrammetry techniques in forensic science, particularly for documenting challenging surfaces. It points out the need for further research, given its limitations in sample size and the absence of extensive parameter testing and quantitative analysis.

Correction of uneven illumination in microscopic image through robust brightness distribution estimation and deviation rectification

For diagnostic purposes, the automatic microscopic scanning system can scan and stitch multiple slide images together to produce a Whole Slide Image. This process provides a clear, high-resolution picture of the slide sample under the high-power objective lens of the microscope, enabling accurate diagnosis and analysis. However, uneven illumination affects every image acquired by a microscope, resulting in the existence of artifacts. In this paper, a novel retrospective approach based on robust brightness distribution estimation and deviation rectification is proposed. Least squares estimation and Cauchy estimation with a smooth regularization term are used to obtain the accurate estimation of background illumination distribution. Then the deviation map is given based on the deviation function of the two directions for illumination correction. This method leverages the statistical properties of image sequences to enhance stability and robustness against biological image artifacts. Through experimental validation, this approach successfully eliminates visible edge artifacts that commonly appear between neighboring tiles and exhibits superior performance when compared to other methods.

Image smoothing combining edge-consistency with region-piecewise flatting

Image smoothing constitutes a fundamental task within the realm of computer vision. Effectively preserving the structural integrity of edges during the image smoothing process represents an arduous challenge. Current methodologies persistently encounter issues in adequately exploiting and harnessing the intrinsic value of edge information within images, while simultaneously suffering from the limitation of employing overly simplistic constraints for achieving desirable smoothing outcomes. To solve these problems, we propose a new Edge Consistency and Region Piecewise Flatting Network (ECRPF-Net). To circumvent the impact of the convolution process on edge-preserving properties, our network adopts the approach of superimposing significant edge information onto the feature layer, while also incorporating a weak structure reinforcement module. To efficiently preserve the edge structure, we incorporate an edge consistency module (ECM), which utilizes the edge-response consistency relationship between the input and output images to ensure the preservation of edges. To enhance the quality of image smoothing and mitigate the occurrence of edge artifacts, we introduce the Region Piecewise Flatting Module (RPFM). This module partitions the image into different regions based on the similarities and differences in edge response features, and applies a flexible sub-region smoothing approach to constrain the final output, ensuring superior smoothing results. Experimental results demonstrate the excellent performance of the ECRPF-Net in preserving the prominent edge structure of the image, achieving more visual-appealing smoothing outcomes, and surpassing the majority of existing methods on public datasets.

Edge-Driven Multi-Agent Reinforcement Learning: A Novel Approach to Ultrasound Breast Tumor Segmentation.

A segmentation model of the ultrasound (US) images of breast tumors based on virtual agents trained using reinforcement learning (RL) is proposed. The agents, living in the edge map, are able to avoid false boundaries, connect broken parts, and finally, accurately delineate the contour of the tumor. The agents move similarly to robots navigating in the unknown environment with the goal of maximizing the rewards. The individual agent does not know the goal of the entire population. However, since the robots communicate, the model is able to understand the global information and fit the irregular boundaries of complicated objects. Combining the RL with a neural network makes it possible to automatically learn and select the local features. In particular, the agents handle the edge leaks and artifacts typical for the US images. The proposed model outperforms 13 state-of-the-art algorithms, including selected deep learning models and their modifications.

Single-image super-resolution based on an improved asymmetric Laplacian pyramid structure

Large-scale factor image super-resolution whose scale factor is greater than 4 is significant in real-world applications for single image super-resolution. The current image super-resolution techniques for large-scale factor, however, frequently upsample low-resolution images in a single pass, leading to edge artifacts in the reconstructed images. In this article, we provide an improved asymmetric Laplacian pyramid network to further realize large-scale factor image super-resolution and fully utilize various size features. A distinct architecture is applied at each layer of the pyramid for improving feature extraction. We extend the first layer of the pyramid with a lightweight transformer design, which enables the model to efficiently collect the contextual information in the sequence by utilizing the multi-headed attention mechanism. Additionally, we combine improved dense skip connections with recursive operations to form a deep dense recursive convolutional neural network that fuses low-level and high-level features while broadening the network's receptive field. The quantitative and qualitative analysis on benchmark dataset's demonstrate that our method provides superior performance in both PSNR and SSIM and is more in line with human visual perception.

CDS-Net: Cooperative dual-stream network for image manipulation detection

To accurately locate manipulated regions, many existing approaches employ a dual-stream framework to extract a wide range of manipulation clues, including local noise, edge artifacts, and global inconsistency. However, these approaches treat each stream in isolation and fail to consider the complementary and mutual guidance ability between the streams. Moreover, we notice the use of vanilla vision transformers in previous approaches can result in disruptions of object semantics, causing incomplete predictions. To address these challenges, we introduce the cooperative dual-stream network (CDS-Net) comprising an RGB Stream and a Noise Stream. In the Noise Stream, we propose a K-means Transformer (KT) that encourages both inter-patch and intra-patch information transmission to mitigate the semantic fragmentation phenomenon caused by patch partitioning. Additionally, we introduce a novel Feature Interaction Block (FIB) that explicitly encourages cross-stream collaboration at each encoding stage. Comprehensive experiments on publicly available datasets demonstrate the effectiveness and robustness of CDS-Net.

Mathematical Simulation in Nuclear Medicine for Optimization Diagnostic Accuracy of SPECT/CT

Purpose: To develop the method of mathematical simulation in the field of nuclear medicine and its
 practical application in research aimed at improving the diagnostic accuracy of the SPECT/CT method.
 The basic principles of the method of mathematical simulation in nuclear medicine and the main modules of the software package “Virtual Platform for Simulation Tests of the SPECT/CT Method”, created
 at the laboratory for simulation in nuclear medicine of Novosibirsk State University and the Institute of
 Theoretical and Applied Mechanics.
 Material and methods: The main principles of the developed software package are the realism of the ‘virtual patient’ mathematical model, the accuracy in modeling of physical processes in visualization, as
 well as simulation conducting close to clinical practice. All studies were carried out in collaboration
 with clinicians. The software complex was verified by comparison with clinical data. Numerical experiments have shown a close correspondence between the results of clinical and virtual studies. In simulation tests, the same errors were obtained on images that were observed on clinical images. Simulation
 computer tests were carried out using the software package “Virtual Platform...” in the field of nuclear
 oncology, cardiology and neurology, aimed at studying the accuracy of images of pathological foci to assess the possibility of switching to quantitative SPECT, as well as optimizing the protocol for examining
 patients.
 Results: Simulation tests have shown that in order to move to quantitative SPECT, it is not enough to be
 limited to the development of a methodology for calibrating SPECT systems for a particular radionuclide. There are problems without understanding and solving which it is impossible to talk about the diagnostic accuracy of the quantitative SPECT method. Such problems are edge artifacts that appear on
 the images of pathological foci, and the rule of stopping the iterative algorithm when the values of activity in the area of interest (pathological focus) that are closest to the true values are reached. A stopping
 criterion based on Pearson's modified chi-square test of goodness of fit is proposed. There is a significantly good correlation between the proposed stop criterion and the minimum RMS error of the image
 reconstruction. The results of simulation modeling with the aim of optimizing SPECT examinations of
 brain perfusion demonstrated the possibility of reducing the data recording time compared to the standard protocol by at least two times.
 Conclusion: The computer simulation method presented in this paper is a practical technology that
 contributes to the optimization and development of a quantitative SPECT method to achieve the best
 possible results in the imaging of pathological foci. Further development of the software package is focused on applications in radionuclide therapy and theranostics.

An Optimized Error Compensation Method for Phase Measurement Profilometry

Phase measurement profilometry (PMP) is primarily employed to analyze the morphology of a functional surface with precision. Historically, one of the most complex and persistent challenges in PMP has been reducing errors stemming from inconsistent indicators at the edges of a surface. In response to this challenge, we propose an optimized error compensation methodology specifically designed to handle edge artefacts. This methodology introduces the Hilbert transform and object surface albedo as tools to detect the edges of the artefact region that need to be compensated. Moreover, we analyze the characteristics of the sinusoidal fringe waveform propagation direction and investigate the reconstruction results of the fringe vertical to the current directions to compensate for edge artefacts. The experimental results for various objects show that the optimized approach can compensate for edge artefacts by projecting in two directions and reducing the projection by half. The compensated root mean square error (RMSE) for planar objects can be reduced by over 45%.

Deep learning study on the mechanism of edge artifacts in point spread function reconstruction for numerical brain images.

Non-blinded image deblurring with deep learning was performed on blurred numerical brain images without point spread function (PSF) reconstruction to obtain edge artifacts (EA)-free images. This study uses numerical simulation to investigate the mechanism of EA in PSF reconstruction based on the spatial frequency characteristics of EA-free images. In 256 × 256 matrix brain images, the signal values of gray matter (GM), white matter, and cerebrospinal fluid were set to 1, 0.25, and 0.05, respectively. We assumed ideal projection data of a two-dimensional (2D) parallel beam with no degradation factors other than detector response blur to precisely grasp EA using the PSF reconstruction algorithm from blurred projection data. The detector response was assumed to be a shift-invariant and one-dimensional (1D) Gaussian function with 2-5mm full width at half maximum (FWHM). Images without PSF reconstruction (non-PSF), PSF reconstruction without regularization (PSF) and with regularization of relative difference function (PSF-RD) were generated by ordered subset expectation maximization (OSEM). For non-PSF, the image deblurring with a deep image prior (DIP) was applied using a 2D Gaussian function with 2-5mm FWHM. The 1D object-specific modulation transfer function (1D-OMTF), which is the ratio of 1D amplitude spectrum of the original and reconstructed images, was used as the index of spatial frequency characteristics. When the detector response was greater than 3mm FWHM, EA in PSF was observed in GM borders and narrow GM. No remarkable EA was observed in the DIP, and the FWHM estimated from the recovery coefficient for the deblurred image of non-PSF at 5mm FWHM was reduced to 3mm or less. PSF of 5mm FWHM showed higher spatial frequency characteristics than that of DIP up to around 2.2cycles/cm but was lower than the latter after 3cycles/cm. PSF-RD showed almost the same spatial frequency characteristics as that of DIP above 3 cycles/cm but was inferior below 3cycles/cm. PSF-RD has a lower spatial resolution than DIP. Unlike DIP, PSF lacks high-frequency components around the Nyquist frequency, generating EA. PSF-RD mitigates EA while simultaneously suppressing the signal, diminishing spatial resolution.

Visually Encrypted Watermarking for Ordered-Dithered Clustered-Dot Halftones

Visual encryption and show through watermarking are widely used techniques to hide secret data in halftone images. The secret watermark can be quickly revealed when the halftone images are printed in transparency and overlaid on each other. The present studies emphasize developing a show-through watermarking technique for the clustered-dot halftone types. The proposed method exploits the properties of various configurations of dither array screens constructed using distinct Gaussian filters to embed watermarks. Two approaches are proposed, i.e., adjacent dither array pairs and the dither array translations. The optimal configuration of dither array parameters is developed to obtain maximum contrast and imperceptibility. Moreover, a new edge screen dithering is proposed to eliminate the edge artifacts, resulting in smooth screen transitions. As efficient ordered dithering is adopted for the watermark embedding, the joint watermarking and halftoning can be performed without additional computations. In comparison to the existing state-of-the-art show-through watermarking techniques, the proposed method can present superior image quality, computational simplicity, and decoded watermarks can be perceived with clear contrast when the images are overlaid with each other.

Depth-of-field expansion method based on multidimensional structure and edge-guided correction.

Multi-focus image fusion is a method to extend the depth of field to generate fully focused images. The effective detection of image focusing pixels and the optimization of image regions are the key to it. A method based on multidimensional structure and edge-guided correction (MSEGC) is proposed. The pixel-level focusing evaluation function is redesigned to preserve image details and non-texture regions. Edge-guided decision correction is used to suppress edge artifacts. With public data and semiconductor detection images for verification, the results show that compared with other methods, the objective evaluation is improved by 22-50%, providing better vision.

A new fractional-order variational approach for joint de-hazing and segmentation of images

Segmenting outdoor images in the presence of haze, fog or smog (which fades the colors and diminishes the contrast of the observed objects) has been a challenging task in image processing with several important applications. In this paper, we propose a new fractional-order variational model that will be able to de-haze and segment a given image simultaneously. The proposed method incorporates the atmospheric veil estimation based on the dark channel prior (DCP). This transmission map can reduce significantly the edge artifacts and enhance estimation precision in the resulting image. The transmission map is then changed over to the high-quality depth map, with which the new fractional-order variational model can be framed to look for the haze free segmenting image for both grey and color outdoor images. An explicit gradient descent scheme is employed to find efficiently the minimizer of the proposed energy functional. Experimental tests on real world scenes show that the proposed method can jointly de-haze and segment hazy or foggy images effectively and efficiently.

Impact of list-mode reconstruction and image-space point spread function correction on PET image contrast and quantitative value using SiPM-based PET/CT system.

We evaluate the effects of list-mode reconstruction and the image-space point spread function (iPSF) on the contrast and quantitative values of positron emission tomography (PET) images using a SiPM-PET/CT system. The evaluation is conducted on an NEMA body phantom and clinical images using a Cartesion Prime SiPM-PET/CT system. The signal-to-background ratio (SBR) of the phantom is set to 2, 4, 6, and 8, and all the PET image data are obtained and reconstructed using 3D-OSEM, time-of-flight, iPSF (-/ +), and a 4-mm Gaussian filter with several iterations. The evaluation criteria include % background variability (NB,10mm), % contrast (QH,10mm), iPSF change in QH,10mm (ΔQH,10mm) for edge artifact evaluation, profile curves, visual evaluation of edge artifacts, clinical imaging for the standardized uptake value (SUV) of lung nodules, and SNRliver. NB,10mm demonstrates no significant difference in all SBRs with and without iPSF, whereas QH,10mm is higher based on the SBR with and without iPSF. ΔQH,10mm indicates increased iterations and a larger rate of change (> 5%) for small spheres of < 17mm. The profile curves portrayed almost real concentrations, except for the 10-mm sphere of SBR2 without iPSF; however, with iPSF, an overshoot was observed in the 13-mm sphere of all SBRs. The degree of overshoot increased with increasing iteration and SBR. Edge artifacts were detected at values ≥ 17-22mm in SBRs other than SBR2 with iPSF. Irrespective of the nodal size, SUV and SNRliver improved considerably after iPSF adjustment. Therefore, the effects of list-mode reconstruction and iPSF on PET image contrast were limited, and the overcorrection of the quantitative values was validated using iPSF.

Role of Lesion-to-Background Activity Ratio and Background Activity in Optimization of Reconstruction Protocols for FDG PET/CT Images of Overweight Patients: A Phantom Study

Background: The quality of positron emission tomography/computed tomography (PET/CT) images plays an important role in tumor detection. This imaging method often yields poor-quality images of overweight patients due to the high level of noise, originating from scattering and photon attenuation. Objectives: The point spread function (PSF) is mostly used to enhance the spatial resolution and signal-to-noise ratio (SNR); however, it is known to increase the edge artifacts. The time-of-flight (TOF) principle can reduce edge artifacts in PSF modeling and improve lesion detection, especially in the thorax. The present study aimed to assess these two new techniques by applying different reconstruction parameters. Materials and Methods: An in-house phantom with an inner diameter of 35 cm was used for the simulation of overweight patients. Lesion-to-background ratios (LBRs) of 2: 1 and 8: 1, as well as background activity concentrations of 3 and 5 kBq/cc, were considered in this study. The list-mode data were reconstructed with various reconstruction protocols, numbers of subsets, and filter sizes. Quantitative analyses, including the coefficient of variation (COV), SNR, and recovery coefficient (RC), were also carried out. Moreover, box-and-whisker plots were performed. Results: At LBR of 2: 1, by changing the protocol from ordered subset expectation maximization (OSEM) to OSEM + PSF + TOF, the median value of SNR for 13-mm lesions (37 mm) increased by 39.25% and 53.45% (42.22% and 56.21%), at background activity concentrations of 3 and 5 kBq/cc respectively. However, at LBR of 8: 1, the corresponding values were 33.22% and 48.94% (40.22% and 52.15%) at background activity concentrations of 3 and 5 kBq/cc respectively. Conclusion: The TOF protocols were strongly recommended for both background activity concentrations at LBR of 2: 1 and for the low background activity concentration at LBR of 8: 1, especially when using smaller filter sizes. Moreover, subset numbers of 18 and 24 were appropriate for all protocols. However, a smaller subset number was suitable when a low background activity concentration and a smaller filter size were applied, especially at a lower LBR.