This case emphasizes the need for caution in planning a course of therapy for childhood lead poisoning. Initial and serial evaluations of renal function (urinalysis, BUN, and serum creat inine) are needed. The decision to include BAL in the therapy should also be guided by the presence or absence of G-6-PD deficiency, as BAL can cause intravascular hemolysis in the presence of such deficiency. REFERENCES 1. Pueschel SM, Kapilo L, Schwachman H: Children with an increased lead burden: A screening and follow-up. JAMA 222:462, 1972. 2. Chisolm JJ Jr: Amnioaciduria as a manifestation of renal tubular injury in lead intoxication and a comparison with pattern of amniaciduria seen in other diseases. J PED1ATR 60:117, 1962. 3. Chisolm JJ Jr: Increased lead absorption and lead poisoning (plumbism). In Vaughan VC, McKay R J, Behrman RE, editors: Nelson text of pediatrics, ed 11. Philadelphia. 1979, WB Saunders, p 2025. 4. Foreman H, Finnegan C, Lushaugh CC: Nephotoxic hazard from uncontrolled edathamil calcium-disodium therapy. JAMA 160:1042, 1956. 5. Reuber MD, Bradley JE: Acute versenate nephrosis occurring as a result of treatment of lead intoxication. JAMA 174:263, 1960. 6. Schrier RW: Acute renal failure. Kidney Int 15:205, 1979. 7. Ingelfinger JR, Avner E: Renal disorders. In Graef JW, Cone TE, editors: Manual of pediatric therapeutics. Boston, 1980, Little Brown p 205. 8. Chisolm JJ Jr: The use of chelating agents in the treatment of acute and chronic lead intoxication in childhood. J PEDIATR 73:1, 1968. 9. Smith HD: Pediatric lead poisoning. Arch Environ Health 8:68, 1964. 10. Henderson DA: A follow-up of cases of plumbism in children. Aust Ann Med 3:219, 1954. 11. Tepper LB: Renal function subsequent to childhood plumbism. Arch Environ Health 7:82, 1962.