Russia promotes the application of GLONASS satellite information system in regional economies. In three regions, the system has already been introduced and is widely used, 21 more regions are introducing the system. Experts believe that this process will take from 3 to 5 years. The introduction and integrated use of GLONASS pose a number of organisational and economic problems for regional administrations. One of such problems is the evaluation of economic benefit from GLONASS implementation in the region. Economics has developed a large number of methodological approaches to the calculation of such effects in different fields of satellite information application: Earth's remote probing, crop yield forecasts, forestry, water industry and agricultural monitoring, etc. However, the research shows that attempts to perform a calculation for various fields of satellite information application at a regional level prove the existing approaches to be inefficient due to the difficulties in obtaining initial data. To this effect, the authors developed a normative methodical approach to the calculation of the effect of integrated GLONASS application. This approach is meant to fill the existing gap and makes it possible to evaluate the economic benefit of an integrated GLONASS application for different fields.