In South Asia, particularly India, women face significant challenges stemming from gender discrimination, poverty, and caste-based inequalities. Self-Help Groups (SHGs) have emerged as a pivotal approach to women's empowerment, promoting both economic independence and social awareness. This review paper explores the role of sericulture, specifically the crafting of handicrafts from silk cocoons, as a means of enhancing women's livelihoods in rural areas. By utilizing cut and pierced cocoons, artisans can create a diverse array of decorative and functional products, contributing to both personal income and community development. This innovative use of by- products in handicrafts not only fosters creativity but also promotes self-employment, allowing marginalized women to gain economic agency. Moreover, engaging in cocoon crafting serves as a therapeutic activity, improving mental well-being and providing a sense of purpose. The study emphasizes the importance of integrating bio-crafts into the broader sericulture industry. This integration not only enhances sustainability by making use of waste materials but also provides a reliable income stream for women and their families. The potential for value addition through skilled craftsmanship transforms what would otherwise be discarded into valuable products, contributing to the local economy. Ultimately, these initiatives improve women's economic status and contribute to their social empowerment, offering a multifaceted solution to entrenched gender inequalities in South Asia. By equipping women with skills and resources, fostering community support, and promoting environmentally sustainable practices, the crafting of silk cocoon handicrafts exemplifies a holistic approach to addressing the challenges faced by women in rural areas. Through this innovative model, women can achieve greater independence, enhance their social standing, and participate actively in their communities, paving the way for a more equitable and empowered society.