Eco-design practices are still incipient in Brazilian furniture industries, although some improvement can be identified in recent years. This paper describes the performance of an industrial furniture cluster located in Southern Brazil regarding such practices. An embedded case study involving four companies — two manufacturers and two suppliers — was carried out using in-depth interviews. It enabled to depict particularities of how these companies deal with sustainable aspects of design in their respective business. Critical issues identified as obstacles for eco-design implementation in these industries were: control of both, productive process and product durability; product distribution; rational use of space for transportation and storage. Minor difficulties were identified regarding the lack of renewable energy sources and the scarcity of knowledge dissemination. Such hurdles could provide opportunities and support future eco-design strategy implementation, improving the competitiveness and contributing for the eco-efficiency of the Brazilian furniture industry.