Quantitative data on predation of white-tailed deer (Odocoileus virginianus) by wolves ( Canis lupus) in east-central Ontario were obtained by following a pack of eight wolves from January 11 to March 20, 1969. Data on sex and age of deer killed during the winters of 1964 to 1969 and success of hunts by wolves in 1968 and 1969 have been included. During the main winter of study, the pack travelled a total of 327 km over a period of 46 days for an average daily travel rate of 7.1 km. The maximum range of the group during the period of surveillance encompassed 224 km2. The pack killed 29 deer during 63 days, or one deer per 2.2 days. Distances travelled between kills ranged from 0.3 to 43.4 km and averaged 14.7. The amount olf food available per wolf per day was 3.67 kg. The calculated daily food consumption was 0.10 kg per kg of wolf per day. The average age (2.43) of deer killed by wolves was greater than the average age ( 2.02 ) of deer killed by hunters. The sex ratio of 42 adult deer killed by wolves was 250 males:l00 females; in a saxnple of 290 hunter-killed deer the ratio was 92:100. In 1968, the hunting success of wolves was 25 percent compared with 63 percent in 1969. It was calculated that during the 5-month winter period, the wolves removed 9 to 11 percent of the 730 deer present when winter began. The timber wolf has recently been the subject of several detailed field studies ( Murie 1944, Gowan 1947, Thompson 1952, Stenlund 1955, Mech 1966, Shelton 1966, Pimlott et al. 1969, Mech and Frenzel 1971). In these investigations, many aspects of wolf ecology received attention, but the primary objective in each was an attempt to determine the impact of wolves on their principal prey. A complete assessment of this problem requires that the following be known: the number of wolves in an area, the number of prey animals in the same area, and the rate at which the wolves remove the prey. Except for the studies by NIech (1966), Shelton (1966), and Mech and Frenzel (1971), all of these investigations have lacked quantitative data on the interrelations of wolves and prey. Predation rates have been the most difficult to estimate. The present study provides quantitative data on predation of white-tailed deer by wolves in east-central Ontario during winter. Most of the information was obtained while following a pack of eight wolves from January 11 to March 20, 1969. Data on sex and age of deer killed during the winter from 1964 to 1968 and success of hunts by wolves in 1968 have been included. The assistance of P. Odorizzi during the winters of 1968 and 1969 and of R. Odorizzi during the winter of 1969 is acknowledged. I thlank the many personnel of the Fish and Wildlife Branch and the Research Branch, Ontario Department of Lands and Forests, who assisted in various capacities. R. O. Standfield reviewed the manuscript.