East Orange Research Articles

Inhibiting morris hepatoma growth in rats by blocking late cholesterol synthesis: [formula omitted] GI Lab VA Medical Center, East Orange, NJ 0701B

Inhibiting morris hepatoma growth in rats by blocking late cholesterol synthesis: [formula omitted] GI Lab VA Medical Center, East Orange, NJ 0701B

Hepatic cholesterol 7β-hydroxylase (CH 7β-OHase) activity correlates with hepatic ursodeoxycholic acid (UDCA) synthesis in the guinea pig (GP): [formula omitted] Dept. of Medicine, VA Medical Center, East Orange, NJ & UMD-NJ Medical School, Newark, NJ

Hepatic cholesterol 7β-hydroxylase (CH 7β-OHase) activity correlates with hepatic ursodeoxycholic acid (UDCA) synthesis in the guinea pig (GP): [formula omitted] Dept. of Medicine, VA Medical Center, East Orange, NJ & UMD-NJ Medical School, Newark, NJ

Increasing hepatic cholesterol 7α-hydroxylase reduced plasma cholesterol concentrations in rabbits: [formula omitted] VA Medical Center, East Orange, NJ 07018 and South Florida Univ.

Increasing hepatic cholesterol 7α-hydroxylase reduced plasma cholesterol concentrations in rabbits: [formula omitted] VA Medical Center, East Orange, NJ 07018 and South Florida Univ.

Preferential sterol transport from HDL to bile . Dept. of Medicine, Boston and East Orange VA Medical Centers, Boston Univ. Sch. of Medicine, Boston, MA, and UMDNJ-NJ, Newark, NJ

Preferential sterol transport from HDL to bile . Dept. of Medicine, Boston and East Orange VA Medical Centers, Boston Univ. Sch. of Medicine, Boston, MA, and UMDNJ-NJ, Newark, NJ

15. Assessing the contribution of lead to hypertension and renal failure by in vivo tibial K XRF

VA Medical Center, East Orange, NJ, UMDNJ-New Jersey Medical School/Robert Wood Johnson Medical School, Brookhaven National Laboratory, Upton, NY, USA

A multidisciplinary approach improved outcome in patients with portacaths: F. Valena, RN, MSN, CIC,∗ E. Yamaguchi, MD. VA Medical Center, East Orange, NJ

A multidisciplinary approach improved outcome in patients with portacaths: F. Valena, RN, MSN, CIC,∗ E. Yamaguchi, MD. VA Medical Center, East Orange, NJ

Ursodeoxycholic acid (UDCA), a hydrophilic bile acid, is concentrated in the water soluble fraction of feces: [formula omitted]1, G. Salen 1, K.R. Rapole 1, H. Holubek 2 and D. Earnest 2. 1NJ Med. School, Newark and VA Med. Center, East Orange, NJ and 1Univ. of Arizona College of Med., Tucson, AZ

Ursodeoxycholic acid (UDCA), a hydrophilic bile acid, is concentrated in the water soluble fraction of feces: [formula omitted]1, G. Salen 1, K.R. Rapole 1, H. Holubek 2 and D. Earnest 2. 1NJ Med. School, Newark and VA Med. Center, East Orange, NJ and 1Univ. of Arizona College of Med., Tucson, AZ

Proof of the enzyme defect in the Smith-Lemliopitz syndrome (SLOS): Markedly decreased conversion of 7-dehydrocholesterol (7DHC) to cholesterol (CH) in cultured fibroblasts from homozygotes: A. Honda, [formula omitted], G Salen, AK Batta, S Shefer, T. Chen. Depts. of Medicine & Pathology, VA Medical Cntr, East Orange, NJ & UMDNJ-NJ Medical School, Newark, NJ

Proof of the enzyme defect in the Smith-Lemliopitz syndrome (SLOS): Markedly decreased conversion of 7-dehydrocholesterol (7DHC) to cholesterol (CH) in cultured fibroblasts from homozygotes: A. Honda, [formula omitted], G Salen, AK Batta, S Shefer, T. Chen. Depts. of Medicine & Pathology, VA Medical Cntr, East Orange, NJ & UMDNJ-NJ Medical School, Newark, NJ

Markedly inhibited 7-dehydrocholesterol-Δ 7-reductace activity in liver microsomes from Smith-Lemli-Opitz homozygotes : [formula omitted], G. Salen, A.K. Batta, G.S. Tint. UMD-NJ Medical School, Newark, NJ, VA Medical Center, East Orange, NJ

Markedly inhibited 7-dehydrocholesterol-Δ 7-reductace activity in liver microsomes from Smith-Lemli-Opitz homozygotes : [formula omitted], G. Salen, A.K. Batta, G.S. Tint. UMD-NJ Medical School, Newark, NJ, VA Medical Center, East Orange, NJ

Collaboration to reduce cost of regulated waste at a department of veterans affairs medical center: A. Simmons, RN, MSN, CIC,∗ F. Valena, RN, MSN, CIC, G. B. Bradley III, BA, J. Ralston, BS, MS. VA Medical Center, East Orange, NJ

Collaboration to reduce cost of regulated waste at a department of veterans affairs medical center: A. Simmons, RN, MSN, CIC,∗ F. Valena, RN, MSN, CIC, G. B. Bradley III, BA, J. Ralston, BS, MS. VA Medical Center, East Orange, NJ

Treatment of the cholesterol synthetic defect in a rat model of the Smith-Lemli-Opitz syndrome: [formula omitted], G Salen, S Shefer, G Ness, T Chen, GS Tint. GI Lab, VA Medical Center, East Orange, NJ 07018

Treatment of the cholesterol synthetic defect in a rat model of the Smith-Lemli-Opitz syndrome: [formula omitted], G Salen, S Shefer, G Ness, T Chen, GS Tint. GI Lab, VA Medical Center, East Orange, NJ 07018

Preface

1Director of Outcomes Research, Kessler Institute for Rehabilitation, East Orange, New Jersey, Assistant Professor, Physical Medicine and Rehabilitation, UMDNJ/New Jersey Medical School, West Orange, New Jersey 2Director of Research, Department of Physical Medicine and Rehabilitation, Santa Clara Valley Medical Center San Jose, California, Issue Editors

A phase II trial of alternating chemotherapy in patients with inoperable non-small cell lung cancer : Howard LM, Kasimis BS, Gramer EM, Ruddy P, Hiremath V, Pokorney ES. Veterans Affairs Medical Center, 385 Tremont Avenue, East Orange, NJ07018. Am J Clin Oncol Cancer Clin Trials 1994;17:83–85

A phase II trial of alternating chemotherapy in patients with inoperable non-small cell lung cancer : Howard LM, Kasimis BS, Gramer EM, Ruddy P, Hiremath V, Pokorney ES. Veterans Affairs Medical Center, 385 Tremont Avenue, East Orange, NJ07018. Am J Clin Oncol Cancer Clin Trials 1994;17:83–85

Molecular Response to Calcium Channel Blockers Expressed during Reperfusion following Acute Renal Ischemia

Annals of the New York Academy of SciencesVolume 723, Issue 1 p. 451-453 Molecular Response to Calcium Channel Blockers Expressed during Reperfusion following Acute Renal Ischemia MITCHELL H. BAMBERGER, MITCHELL H. BAMBERGER East Orange VA Medical Center, Section of Urology (112), 385 Tremont Avenue, East Orange, New Jersey 07018-1095 Address correspondence to: Section of Urology, The Hitchcock Clinic-Keene, 590 Court Street, Keene, NH 03431.Search for more papers by this authorLIFEN QIEN, LIFEN QIEN East Orange VA Medical Center, Section of Urology (112), 385 Tremont Avenue, East Orange, New Jersey 07018-1095Search for more papers by this author MITCHELL H. BAMBERGER, MITCHELL H. BAMBERGER East Orange VA Medical Center, Section of Urology (112), 385 Tremont Avenue, East Orange, New Jersey 07018-1095 Address correspondence to: Section of Urology, The Hitchcock Clinic-Keene, 590 Court Street, Keene, NH 03431.Search for more papers by this authorLIFEN QIEN, LIFEN QIEN East Orange VA Medical Center, Section of Urology (112), 385 Tremont Avenue, East Orange, New Jersey 07018-1095Search for more papers by this author First published: June 1994 https://doi.org/10.1111/j.1749-6632.1994.tb36775.xCitations: 3 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume723, Issue1Cellular, Biochemical, and Molecular Aspects of Reperfusion InjuryJune 1994Pages 451-453 RelatedInformation

Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans

Independent carcinogenic effects of alcohol drinking and tobacco smoking as well as their interaction can be usefully studied in a population of heavy drinkers and smokers. A hospital-based case-control study was conducted during 1972 to 1983 in a large Veterans hospital in East Orange, New Jersey. A total of 359 oral cavity-oropharynx cancer cases and 2280 controls were interviewed according to tobacco smoking, use of smokeless tobacco, alcoholic beverage, coffee and tea drinking, race, family origin, religion, and occupation as bartender. Odds ratio of oral cancer increased up to the level of 35 cigarettes per day and 21 whiskey equivalents per day: no further increase was found for higher level of exposure to either factor. A protective effect of quitting smoking was found, but the number of former smokers was small. No difference occurred in oral cancer risk according to type of alcoholic beverage drunk. An interaction effect compatible with a multiplicative model was found between the two exposures. Blacks were at lower risk than whites, and, in the latter group, individuals of Italian origin were at lower risk than individuals from northern or central European countries. Alcohol drinking and tobacco smoking were responsible for the majority of oral cancer cases in this population of US Veterans.

Accuracy of disincorporation for identification of vascular graft infection: Frank T. Padberg, Jr., MD, Sharon M. Smith, PhD, and Robert H. K. Eng, MD, Veterans Affairs Medical Center, East Orange, N.J.

Objective: The presence or absence of prosthetic graft incorporation with surrounding tissue was assessed relative to bacterial culture results, using enhanced microbiologic culture techniques. Design: Criterion standard. Setting: University and Veterans Affairs hospital. Patients: Prosthetic samples were removed from 113 aortofemoral, extra-anatomic, infrainguinal, and hemoaccess sites at the time of vascular reoperative surgery. Harvested grafts were sonicated. Density of organisms was determined by quantitative culture. Main Outcome Measures: The culture result was predicted from the status of prosthetic incorporation or disincorporation as determined at surgery. For purposes of this study, any bacterial growth represented graft infection. Results: Cultures positive for bacteria were obtained from 31 sites; cultures with no growth, from 82. Thirty-one of the 113 sites were disincorporated, of which 23 yielded cultures positive for bacteria, and eight, no growth. The remaining 82 sites were well incorporated, of which 74 yielded cultures negative for bacteria, and eight, bacterial growth. Sixteen (14%) incorrect predictions were noted. The concurrence of disincorporation and a culture positive for bacteria relative to all culture-positive grafts (sensitivity) was 74%. The concurrence of incorporation and cultures negative for bacteria relative to all culture-negative grafts (specificity) was 90% in prostheses implanted for longer than 2 weeks; in prostheses implanted for longer than 12 weeks, specificity was 97%. Conclusions: The surgical finding of incorporation or disincorporation accurately predicted the culture result in 89% of the sites. Disincorporation correlated with presence of bacteria in 71%; incorporation reliably excluded the presence of bacteria in 97%

Carotid arterial trauma: Assessment with the Glasgow Coma Scale as a guide to surgical management: Edwin P. Teehan, MD, Frank T. Padberg, Jr., MD, Robert W. Hobson II, MD, Peter N. Thompson, MD, Bing C. Lee, MD, and Vincent Milazzo, MD, Veterans Affairs Medical Center, East Orange, N.J.

Carotid arterial trauma: Assessment with the Glasgow Coma Scale as a guide to surgical management: Edwin P. Teehan, MD, Frank T. Padberg, Jr., MD, Robert W. Hobson II, MD, Peter N. Thompson, MD, Bing C. Lee, MD, and Vincent Milazzo, MD, Veterans Affairs Medical Center, East Orange, N.J.

Assessment of the efficiency of the use of sterile cartridge needle units vs conventional single and multidose vials

Assessment of the efficiency of the use of sterile cartridge needle units vs conventional single and multidose vials

Reassessment of lead exposure in New Jersey using GIS technology

In order to prevent children's exposure to lead, a variety of sources must be controlled. The New Jersey Department of Environmental Protection and Energy (NJDEPE) is using its Geographic Information System to identify areas within Newark, East Orange, and Irvington, New Jersey, where there may be greater environmental exposure to lead. Sensitive populations are identified through the U.S. Bureau of the Census information. Blood screening data provided by the New Jersey Department of Health (NJDOH) provide reported patterns of elevated blood lead in the study area. Comparisons of these spatial patterns will assist the NJDEPE in its soil sampling activities and lead exposure research, will provide information for public education, and will provide valuable information on sections of the study area where further screening and public education may be needed.

Editorial

When we got married and were appointed to a small congregation in East Orange, New Jersey, the Canadian half of the couple became a 'resident alien,' going to the post office annually to register; the government could thus keep track of possible subversives, however improbable. When we moved to Toronto, the American half of the couple became a 'landed immigrant.' We hadn't clambered out of a ship in Halifax (we actually entered by auto at Sarnia), but we had arrived.