The South China Sea (SCS) is well connected with the western Pacific and influenced by the East Asian monsoon. We have examined temporal variations in radiocarbon marine reservoir ages (R) and regional marine reservoir corrections (Delta R) of the SCS during the Holocene using paired measurements of AMS C-14 and TIMS Th-230 on 20 pristine corals. The results show large fluctuations in both R and Delta R values over the past 7500 years (yrs) with two distinct plateaus during 7.5-5.6 and 3.5-2.5 thousand calendar years before present (cal ka BP). The respective weighted mean Delta R values of these plateaus are 151 +/- 85 and 89 +/- 59 yrs, which are significantly higher than its modern value of -23 +/- 52 yrs. This suggests that using a constant modern Delta R value to calibrate C-14 dates of the SCS marine samples will introduce additional errors to the calibrated ages. Our results provide the first database for the Holocene R and Delta R values of the SCS for improved radiocarbon calibration of marine samples. We interpret the two Delta R plateaus as being related to two intervals with weakened El Nino - Southern Oscillation (ENSO) and intensified East Asian summer monsoon (EASM). This is because the C-14 content of the SCS surface water is controlled by both the C-14 concentration of the Pacific North Equatorial Current (NEC) which is in turn influenced by ENSO-induced upwelling along the Pacific equator and vertical upwelling within the SCS as a result of moisture transportation to midlatitude region to supply the EASM rainfall.