Cosmic ray research in Mexico dates from the early 1930s with the work of the pioneering physicist, Manuel Sandoval Vallarta and his students from Mexico. Several experiments of international significance were carried out during that period in Mexico: they dealt with the geomagnetic latitude effect, the north–south and west–east asymmetry of cosmic ray intensity, and the sign of the charge of cosmic rays. The international cosmic ray community has met twice in Mexico for the International Cosmic Ray Conferences (ICRC): the fourth was held in Guanajuato in 1955, and the 30th took place in Mérida, in 2007. In addition, an international meeting on the Pierre Auger Collaboration was held in Morelia in 1999, and the International Workshop on Observing UHE Cosmic Rays took place in Metepec in 2000. A wide range of research topics has been developed, from low-energy Solar Energetic Particles (SEP) to the UHE. Instrumentation has evolved since the early 1950s, from a Simpson type neutron monitor installed in Mexico City (2300 m asl) to a solar neutron telescope and an EAS Cherenkov array, (within the framework of the Auger International Collaboration), both at present operating on Mt. Sierra La Negra in the state of Puebla (4580 m asl). Research collaboration has been undertaken with many countries; in particular, the long-term collaboration with Russian scientists has been very fruitful.