Early Winter Research Articles

Blowflies are potential vector for avian influenza virus at enzootic area in Japan

High pathogenicity avian influenza (HPAI) poses a significant threat to both domestic and wild birds globally. The avian influenza virus, known for environmental contamination and subsequent oral infection in birds, necessitates careful consideration of alternative introduction routes during HPAI outbreaks. This study focuses on blowflies (genus Calliphora), in particular Calliphora nigribarbis, attracted to decaying animals and feces, which migrate to lowland areas of Japan from northern or mountainous regions in early winter, coinciding with HPAI season. Our investigation aims to delineate the role of blowflies as HPAI vectors by conducting a virus prevalence survey in a wild bird HPAI-enzootic area. In December 2022, 648 Calliphora nigribarbis were collected. Influenza virus RT-PCR testing identified 14 virus-positive samples (2.2% prevalence), with the highest occurrence observed near the crane colony (14.9%). Subtyping revealed the presence of H5N1 and HxN1 in some samples. Subsequent collections in December 2023 identified one HPAI virus-positive specimen from 608 collected flies in total, underscoring the potential involvement of blowflies in HPAI transmission. Our observations suggest C. nigribarbis may acquire the HPAI virus from deceased wild birds directly or from fecal materials from infected birds, highlighting the need to add blowflies as a target of HPAI vector control.

Personalized Full-Body In-Bed Gym at home: lessons from personal experiences

Muscles and mobility deteriorate with age, and exercising is the only sure countermeasure. It is useful to offer safe and toll-free rehabilitation training, such as the Full-Body In-Bed Gym, easy to learn and perform at home. Based on my own experience, I suggest a 10-20-minute daily routine of easy and safe physical exercises that may improve the main 200-300 skeletal muscles used for everyday activities. Many of the exercises can be performed in bed (Full-Body In-Bed Gym), so hospital patients can learn this light workout before leaving the hospital. The routine consists of a series of repetitions of bodyweight exercises to be performed one after the other, without time breaks in between. Alternating sequences of arm and leg exercises are followed by moving body parts in lying and sitting positions in bed and by standing and sitting down. Progressive improvements can be tested by a series of push-ups on the bed or the floor. Starting from 3-5, the number of repetitions is increased by adding 5 more every week. To maintain or even shorten the total daily time of workout, each movement is then speeded up. The devoted time every morning (or at least 5 days a week) to train all the major muscles of the body can remain under 15 minutes. Because there are no breaks during and between sets, the final push-ups become very challenging. At the end of the daily workout, heart rate, depth, number of spontaneous ventilations, and frontal perspiration increase for several tens of minutes. Here is an example of how to implement the progression of the Full-Body In-Bed Gym, presenting an educational case report of a trained 80-year-old person in stable pharmacological management. Details of the workouts and the related results are presented in the 2024 book, How to Rejuvenate at 80’s. Positive results on quality of life, mental wellness, and persistence in a group of older adults were recently reported in a scientific publication. Although performed in bed, in addition to strengthening the main muscles, ventilatory ones included, Full-Body In-Bed Gym at home is a resistance training equivalent to a short jog. Started in early winter and continued regularly throughout spring and summer, Full-Body In-Bed Gym can help maintain the independence and mental wellness of elderly people. It is a simple approach that deserves further clinical trials.

Micro and macro urban heat islands in an industrial city: Bradford, UK

The urban heat island (UHI) phenomenon refers to the temperature difference(s) between urban/built environments and suburban/natural areas. It affects energy use, health, water quality, and in brief, the quality of life in cities. Understanding the magnitude of this issue could help urban planners and decision makers to better implement green interventions into their cities. This paper shows the results of field measurements carried out to study the UHIs in Bradford, as one of the most deprived cities in the UK with minimum green infrastructure. In the first phase of the study, air temperatures were measured in twenty locations (four areas) with different land covers in Bradford. These measurements were called micro UHI study, as the air temperatures were measured in areas within the boundaries of the city. Data were collected in late summer and early winter. The results showed that the UHI is more sensible in the colder day (with average 0.6 °C cooler air temperature in a green area compared to the city centre). Greener areas experienced higher wind and lower air temperatures compared to dense urban settings in December. In the second phase of the study (macro scale), diurnal air temperatures from a residential (urban) versus a rural site were compared during a heat wave episode (seven days). It was observed that the rural site was 0.8 °C cooler than the residential/urban site. The maximum temperature differences occurred during the nights/early mornings between the two sites (3.2 °C at 5:00am).

A CROSS-SECTIONAL SURVEY STUDY TO EVALUATE THE BALA AND VYADHISAHATWA OF AN INDIVIDUAL WITH REFERENCE TO THE TIME OF CONCEPTION

Bala (physical strength) and Vyadhikshamatwa (Immunity) play a vital role in maintaining the swaasthya (health) of an individual and preventing the occurrence of any vyadhi (diseases). Immunity is a general concern for people who wish to maintain positive health. Common illnesses frequently hamper an individual's day-to-day activities, disturbing the equilibrium of body and mind. It also signifies that an individual's immunity is less, making him ill frequently. The purpose of this study is to know the role of Balavat Purushe Kale (born during the period of the season when strength is naturally strong) in maintaining the Bala and Vyadhikshamatwa of an individual. A close-ended questionnaire consisting of 12 questions and an open-ended questionnaire composed of 5 questions were created to obtain a range of Bala and Vyadhikshamatwa. In this study, it was observed that the range of Bala and Vyadhikshamatwa of individuals whose Ritu of conception comes under Hemanta (early winter) and Shishira (late winter) was found to be good as compared to other Ritu (seasons). It was also observed that there is an influence of factors like intake of satmya ahara (wholesome food), satwa bala (mental strength), nityasevaniya dravyas (pathya-indicated foods) and intake of shadrasayukta ahara (consumption of all six rasas-taste which includes sweet, sour, salt, pungent, bitter, astringent).

Isolation and genetic characterization of multiple genotypes of both H5 and H7 avian influenza viruses from environmental water in the Izumi plain, Kagoshima prefecture, Japan during the 2021/22 winter season

In the 2021/22 winter, one H5N1 and nine H5N8 high pathogenicity avian influenza viruses (HPAIVs) of clade 2.3.3.4b were isolated from the water in crane roosts on the Izumi plain, Japan. Additionally, we isolated low pathogenicity avian influenza viruses (LPAIVs) of five subtypes: H1N1, H4N2, H4N6, H7N7, and H10N4. H5N8 HPAIVs belonging to the G2a group were isolated throughout winter, whereas H5N1 HPAIV belonging to the G2b group were isolated only in early winter. These findings suggest co-circulation of both G2a and G2b HPAIVs in early winter. Although two H7N7 LPAIVs were isolated from cranes’ roost water collected on the same day, the gene constellations of the two isolates were clearly different, indicating the contemporary invasion of at least two different genotypes of H7N7 LPAIVs in the Izumi plain. This study underscores the importance of monitoring both HPAIVs and LPAIVs to understand avian influenza virus ecology in migratory waterfowl populations.

Integrated analysis of ATAC-seq and transcriptomic reveals the ScDof3-ScproC molecular module regulating the cold acclimation capacity of potato

Low temperature severely affects the geographical distribution and production of potato, which may incur cold damage in early spring or winter. Cultivated potatoes, mainly derived from Solanum tuberosum, are sensitive to freezing stress, but wild species of potato such as S. commersonii exhibit both constitutive freezing tolerance and/or cold acclimation tolerance. Hence, such wild species could assist in cold hardiness breeding. Yet the key transcription factors and their downstream functional genes that confer freezing tolerance are far from clear, hindering the breeding process. Here, we used ATAC-seq (Assay for Transposase-Accessible Chromatin with high-throughput sequencing) alongside RNA-seq to investigate the variation in chromatin accessibility and patterns of gene expression in freezing-tolerant CMM5 (S. commersonii), before and after its cold treatment. Our results suggest that after exposure to cold, transcription factors including Dof3, ABF2, PIF4, and MYB4 were predicted to further control the genes active in the synthetic/metabolic pathways of plant hormones, namely abscisic acid, polyamine, and reductive glutathione (among others). This suggests these transcription factors could regulate freezing tolerance of CMM5 leaves. In particular, ScDof3 was proven to regulate the expression of ScproC (pyrroline-5-carboxylate reductase, P5CR) according to dual-LUC assays. Overexpressing ScDof3 in Nicotiana benthamiana leaves led to an increase in both the proline content and expression level of NbproC (homolog of ScproC). These results demonstrate the ScDof3-ScproC module regulates the proline content and thus promotes freezing tolerance in potato. Our research provides valuable genetic resources to further study the molecular mechanisms underpinning cold tolerance in potato.

Tropical Atlantic variability in EC-EARTH: impact of the radiative forcing

Understanding the impact of radiative forcing on climate variability and change in the Tropical Atlantic is crucial for different socio-economic sectors, given their substantial impacts in both local and remote regions. To properly evaluate the effect of a changing climate on the variability, the use of standard transient historical and scenario simulations requires very large ensembles. A computationally cheaper alternative implemented in this study consists of performing two 250-year-long atmosphere-ocean coupled simulations with EC-EARTH 3.3 (CMIP6 version) with fixed radiative forcing at the years 2000 and 2050, representative of present and future climate conditions, respectively. The changes in the leading modes of Tropical Atlantic variability (TAV), including the Atlantic Niño/Niña and the Subtropical North Atlantic pattern, have been assessed in three target seasons: spring (MAM), summer (JJ) and early winter (ND). While the change in sea surface temperature (SST) climatology shows homogeneous warming, the difference between future and present SST variability exhibits a distinct behaviour consistent along the seasonal cycle, with a decrease in the equatorial region and an increase at subtropical latitudes. This study explores the processes associated with the suppressed/enhanced TAV, with a particular focus on the less-explored early winter season. In agreement with previous studies, the Atlantic Meridional Overturning Circulation (AMOC) shows a weakening in strength, but the results also show an increase in variability. The AMOC-related deepening of the equatorial thermocline and the flattening linked to weakened trade winds are consistent with the suppressed SST variability of the Atlantic Niño/Niña. On the other hand, the enhanced SST variability at subtropical latitudes is mainly associated with an increase in turbulent heat flux variability, with a minor contribution of the mixed layer depth variability. Variability in turbulent heat flux is influenced primarily by latent heat flux, connected to changes in precipitation variability.

Long‐Term Variability and Tendencies in Mesosphere and Lower Thermosphere Winds From Meteor Radar Observations Over Esrange (67.9°N, 21.1°E)

AbstractLong‐term variabilities of monthly zonal (U) and meridional winds (V) in northern polar mesosphere and lower thermosphere (MLT, ∼80–100 km) are investigated using meteor radar observations during 1999–2022 over Esrange (67.9°N, 21.1°E). The summer (June‐August) mean zonal winds are characterized by westward flow up to ∼88–90 km and eastward flow above this height. The summer mean meridional winds are equatorward with strong jet at ∼85–90 km and it weakens above this height. The U and V exhibit strong interannual variability that varies with altitude and month or season. The responses of U and V anomalies (from 1999 to 2003) to solar cycle (SC), Quasi Biennial Oscillation at 10 and 30 hPa, El Niño‐Southern Oscillation, North Atlantic Oscillation, ozone (O3) and carbon dioxide (CO2) are analyzed using multiple linear regression. From analysis, significant regions of correlations between MLT winds and above potential drivers vary with altitude and month. The positive responses of U and V to SC (up to 15 m/s/100 sfu) indicates the strengthening of eastward winds in mid‐late winter, and poleward winds in late autumn and early winter. The O3 likely intensifies the eastward and poleward winds (∼100 m/s/ppmv) in winter and early spring. The CO2 significantly influence the eastward flow in late winter and summer (above ∼90–95 km) and strengthen the meridional circulation. The significant positive trend in U peaks in summer, late autumn and early winter (∼0.6 m/s/year), the negative trend in V is more prominent in summer above ∼90–95 km.

The role of storm‐track dynamics in the intraseasonal variability of the winter ENSO teleconnection to the North Atlantic

AbstractThe response of the North Atlantic large‐scale circulation to El Niño–Southern Oscillation (ENSO) exhibits distinct differences between early (November–December) and late (January–February) winter. However, the reasons for this are unclear, particularly regarding the early winter response. Here we examine the role of storm‐track dynamics in influencing the intraseasonal variability of the ENSO teleconnection to the North Atlantic. During late winter there a broad weakening of the eddy heat flux upstream of the North Atlantic storm track during the El Niño phase, which is associated with a broad southward jet shift across North America and the North Atlantic. The late winter response is reinforced by synoptic eddies through enhanced cyclonic wave breaking, consistent with previous studies. However, a stronger teleconnection occurs during early winter. There are modest changes in the North Atlantic eddy heat flux, but strong changes in the upper‐level storm track associated with ENSO, with increased anticyclonic wave breaking during El Niño reinforcing the jet across the central North Atlantic. During early winter there are less frequent northern eddy‐driven jet occurrences in El Niño years and more frequent northern eddy‐driven jet occurrences in La Niña years. These poleward North Atlantic jet excursions typically follow peaks in the eddy heat flux; however, in El Niño years this relationship breaks down and the jet does not transition to the northern position as frequently, despite no clear changes in the upstream eddy heat flux. Composite analysis reveals that precursor storm‐track anomalies upstream over the eastern North Pacific/North America are important in suppressing the poleward jet excursions. These precursors map onto the seasonal mean North Pacific storm‐track anomalies during El Niño. Measured across all years, there is a clear relationship between the mean early winter eastern North Pacific storm‐track activity and eastern North Atlantic eddy‐driven jet, which can explain the early winter ENSO teleconnection to the North Atlantic.

Future changes in the wintertime ENSO-NAO teleconnection under greenhouse warming

El Niño-Southern Oscillation (ENSO) teleconnection to the Euro-Atlantic exhibits strong subseasonal variations, as the North Atlantic Oscillation (NAO) response systematically reverses its phase from early to late winter. Based on two sets of atmospheric model simulations in CMIP6 forced by historical and projected SST, we report a future disappearance of this teleconnection reversal, with the positive early winter ENSO-NAO correlation turning negative and the negative late winter correlation becoming stronger. We suggest that this negative NAO tendency is associated with the strengthening and eastward shift of the ENSO atmospheric teleconnection towards the Euro-Atlantic due to parallel changes in the ENSO tropical convection. While the early winter NAO phase transition is further facilitated by the mean state change in the North Atlantic jet meridional shear, which shifts the ENSO-driven Rossby wave-propagating direction, an intensified stratospheric pathway is demonstrated to play an additional role in strengthening the late winter NAO response.

Different responses of surface air temperature over Eurasia in early and late winter to the autumn Kara–Laptev Sea ice

The Arctic climate is changing rapidly, along with intensified melting of sea ice, which has significant impacts on surface air temperature (SAT) in Eurasia. This study reveals that the subseasonal response of SAT to the autumn Kara–Laptev Sea ice (KLSIC) differs significantly between early and late winter. The response of SAT to KLSIC forms a warm Arctic–cold Eurasia pattern in early winter. Conversely, the negative anomaly response of SAT to KLSIC in late winter is only distributed in the band range of Eurasia, without significant positive SAT anomaly over the Arctic Ocean. After further examination of the separate physical mechanisms involved in early and late winter, it is found that a decrease in KLSIC in autumn can lead to a strengthened Ural high and Siberian high in the Arctic–Eurasia region, which is conducive to cold events in the mid-latitudes of Eurasia in early winter. For late winter, a westward shift in the response of atmospheric circulation to KLSIC leads to a negative anomaly feedback of North Sea surface temperature, which triggers the propagation of Rossby waves to the Sea of Japan through the wave activity flux. Meanwhile, the deep trough of East Asia is strengthened and extends to the southeast, guiding northern cold air to the western Pacific. Our results highlight that different subseasonal effects of sea ice should be considered in Eurasian climate prediction, rather than only consider the effects in winter mean.

An underlying factor of increasing early winter precipitation in the Hokuriku region of Japan in recent decades

AbstractUsing a reanalysis dataset and large‐ensemble simulation results, this study examines a possible factor of increasing trend in early winter precipitation in recent decades in the Hokuriku region of Japan. Monthly precipitation in December has a significant increasing trend after the early 1990s, which is different from those in January and February. The increasing precipitation in December is related to that in the sea surface upward latent heat flux due to intensified winter monsoon circulation and warming sea surface temperatures (SSTs) over the Sea of Japan. December averaged SSTs show a trend pattern in recent decades that is similar to the negative phase of the interdecadal Pacific oscillation (IPO), accompanied by positive trends from the eastern Indian Ocean to the western tropical Pacific. The enhanced trend of convection over the Bay of Bengal is seen; suggesting a combined effect of climatologically high SSTs and IPO‐related warmed SSTs over the region. Trends in recent decades of an upper‐level wavy pattern from South Asia to near Japan along the subtropical jet associated with enhanced convection near the Bay of Bengal and the related pressure drop from Japan to the north are seen, which contribute to intensified winter monsoon circulation.

Connections between low- and high- frequency variabilities of stratospheric northern annular mode and Arctic ozone depletion

Previous studies have demonstrated a dynamical linkage between the ozone and stratospheric polar vortex strength, but only a few have mentioned the persistence of the anomalous vortex. This study uses the complete ensemble empirical mode decomposition with adaptive noise to decompose the winter stratospheric northern annular mode (NAM) variabilities into relatively low frequencies (>4 months) and high frequencies (<2 months) (denoted as NAML and NAMH) and investigates their relationship with the Arctic ozone concentration in March. A closer relationship is found between the Arctic ozone and the NAML, i.e. a persistently strong stratospheric polar vortex in winter (especially February–March) is more critical than a short-lasting extremely strong vortex in contributing to Arctic ozone depletion. We find that a negative NAMH or major stratospheric sudden warming event in early winter could be a precursor for the anomalous depletion of Arctic ozone in March. The NAML changes are further related to the warm North Pacific sea surface temperature (SST) anomalies and ‘central-type’ El Niño-like or La Niña-like SST anomalies in early winter months, as well as cold North Atlantic SST anomalies and higher sea ice concentration in the Barents–Kara Sea from late-autumn to early-spring.

Continuous Introduction of H5 High Pathogenicity Avian Influenza Viruses in Hokkaido, Japan: Characterization of Viruses Isolated in Winter 2022–2023 and Early Winter 2023–2024

High pathogenicity avian influenza (HPAI) has impacted poultry and wild birds globally. The number of H5 HPAI virus (HPAIV) infection cases in wild birds in Hokkaido (Northern Japan) was high in the last two seasons, contributing to virus spillover to resident birds and poultry. Therefore, H5 HPAIVs in birds and mammals in Hokkaido in winter 2022–2023 and 2023–2024 were monitored and viruses were phylogenetically, antigenically, and pathogenetically characterized. Thirty HPAIV isolates were subtyped and pathotyped by sequencing the hemagglutinin (HA) gene of viruses. Phylogenetic analysis of the HA gene revealed that all isolated HPAIVs were categorized into clade 2.3.4.4b and divided into three groups (G2b, G2c, and G2d). Most isolates belonging to subgroup G2d clustered with isolates in winter 2021–2022 in Hokkaido. The other isolates were categorized into two subgroups, G2b and G2c, mainly composed of isolates in Honshu Island in winter 2021–2022 and 2022–2023, respectively. Two H5 HPAIVs isolated in Eastern Russia in spring and autumn 2022 were genetically close to most Hokkaido isolates (G2d), and a virus isolated in Hokkaido in November 2023 was also grouped in subgroup G2d. Further analysis of all eight gene segments identified six types of gene constellations. Cross-hemagglutination inhibition test indicated that the antigenicity of H5 HPAIVs isolated in the last several seasons was similar within them but slightly different from that in the 2010s. Three chicken breeds were intranasally challenged with four representative isolates to assess their pathogenicity. All chickens except one broiler chicken were dead until 5-day postchallenge with different pathogenicity of these viruses. The pathogenicity of one HPAIV strain was significantly lower in broiler chickens than in layer chickens. The mixture of multiple characteristics of HPAIVs in Hokkaido was confirmed by bird migration routes. Thus, many HPAIVs can be brought and scattered anywhere on Earth.

Transitional circulation patterns from full ice cover to ice-off in a seasonally ice-covered lake

There is consensus that under-ice circulation presents multiple phases through the winter, and that different mechanisms dominate each period. In this work, measurements of temperature, water velocity, conductivity, and dissolved oxygen from Lake Massawippi, Quebec, Canada, obtained during the ice-covered season in 2019, were used to characterize the time scales of different winter regimes and transitions among dominating circulation mechanisms. Lake circulation during this period began with a single-cell convection induced by sediment flux pulses in early winter. The single-cell convection decayed into a brief quiescent period. Radiatively driven convection then formed a convectively mixed layer in late winter. The defined mixed layer and temperature structure provided the necessary conditions for the formation of a potential rotational feature, which briefly formed immediately prior to ice break-up. Ice break-up led to complex hydrodynamics that persisted for nearly 28 days following full ice-off. Dissolved oxygen was directly correlated with the varying circulation features throughout the field campaign. This work provides a quantitative measure to delineate the transitions between under-ice regimes and provides novel insights into the subsequent circulation during and after ice break-up.

Vertical measurements of atmospheric CO2 and 14CO2 at the northern foot of the Qinling Mountains in China

The CO2 and 14CO2 levels in air samples from the northern foot of the Qinling Mountains (Xi'an, China) were determined. In 2021, a hexacopter unmanned aerial vehicle sampled air at different heights, from near-ground to 2000 m. The objectives of this study were to determine vertical characteristics of CO2 and 14CO2, the sources of different-height CO2, and the influence of air mass transport. The CO2 concentrations mainly exhibited a slight decreasing trend with increasing height during summer observations, which was in contrast to the increasing trend that was followed by a subsequent gradual decreasing trend during early winter observations, with peak CO2 levels (443.4 ± 0.4–475.7 ± 0.5 ppm) at 100–500 m. The variation in vertical concentrations from 20 to 1000 m in early winter observations (21.6 ± 19.3 ppm) was greater than that in summer observations (14.6 ± 14.3 ppm), and the maximum vertical variation from 20 to ∼2000 m reached 61.1 ppm. Combining Δ14C and δ13C vertical measurements, the results showed that fossil fuel CO2 (CO2ff, 56.1 ± 15.2 %), which mainly come from coal combustion (81.2 ± 3.4 %), was the main contributor to CO2 levels in excess of the background level (CO2ex) during early winter observations. In contrast, biological CO2 (CO2bio) dominated CO2ex in summer observations. The vertical distributions of CO2ff in early winter observations and CO2bio in summer observations were consistent with those of CO2 during early winter and summer observations, respectively. The strong correlation between winter CO2bio and ΔCO (r = 0.81, p < 0.01) indicated that biomass burning was the main contributor to CO2bio during early winter observations. Approximately half of the air masses originated from the Guanzhong Basin during observations. The results provide insights into the vertical distribution of different-sources of atmospheric CO2 in scientific support of formulating carbon emission-reduction strategies.

Vernal growth of vocal control nucleus Area X, but not HVC, precedes gonadal recrudescence in wild black-capped chickadees (Poecile atricapillus).

In temperate-zone songbirds, the neuroanatomical changes which occur in advance of breeding, including the growth of nuclei of the vocal control system, are believed to occur downstream of gonadal recrudescence. However, evidence from wild birds is mixed. Here, we captured black-capped chickadees from the wild in early spring (March-April), summer (August-September), and winter (December-January); in addition to measuring the volumes of two vocal control nuclei (Area X and HVC), we also quantified two indicators of reproductive state (gonads and circulating gonadal steroids). Most birds captured in early spring had regressed gonads and low levels of circulating gonadal steroids, indicating these birds were not yet in full breeding condition. However, these early spring birds still had a significantly larger Area X than winter birds, while HVC did not differ in size across groups. Using data from a previously published seasonal study of black-capped chickadees (Phillmore et al., Developmental Neurobiology, 2015;75:203-216), we then compared Area X and HVC volumes from our early spring group to a breeding group of chickadees captured 3-4 weeks later in the spring. While Area X volume did not differ between the studies, breeding males in Phillmore et al. (2015) had a significantly larger HVC. Taken together, this suggests that the vernal growth of Area X occurs ahead of HVC in black-capped chickadees, and that the overall vernal changes in the vocal control system occur at least partially in advance of the breeding-associated upregulation of the hypothalamic-pituitary-gonadal axis.

Spatiotemporal Trends in Group A Streptococcal Pharyngitis in the United States.

Group A Streptococcus (GAS) causes an estimated 5.2 million outpatient visits for pharyngitis annually in the United States, with incidence peaking in winter, but the annual spatiotemporal pattern of GAS pharyngitis across the United States is poorly characterized. We used outpatient claims data from individuals with private medical insurance between 2010 and 2018 to quantify GAS pharyngitis visit rates across U.S. census regions, subregions, and states. We evaluated seasonal and age-based patterns of geographic spread and the association between school start dates and the summertime upward inflection in GAS visits. The South had the most visits per person (yearly average, 39.11 visits per 1000 people; 95% confidence interval, 36.21-42.01) and the West had the fewest (yearly average, 17.63 visits per 1000 people; 95% confidence interval, 16.76-18.49). Visits increased earliest in the South and in school-age children. Differences in visits between the South and other regions were most pronounced in the late summer through early winter. Visits peaked earliest in central southern states, in December to January, and latest on the coasts, in March. The onset of the rise in GAS pharyngitis visits correlated with, but preceded, average school start times. The burden and timing of GAS pharyngitis varied across the continental United States, with the South experiencing the highest overall rates and earliest onset and peak in outpatient visits. Understanding the drivers of these regional differences in GAS pharyngitis will help in identifying and targeting prevention measures.

Smog the New Unfortunate Reality: A Catastrophe Public Health Concern in Decreasing Life Spans of Pakistani Population

The air pollution that is currently engulfing T Pakistan is a public health emergency. Pakistan's "smog season" begins in the fall and early winter and seems to be getting worse every year. Lahore and other cities in the region frequently rank among the worst places in the world for air quality.1 According to a University of Chicago study, the consequences of the smog will shorten people's lives in Lahore by an average of seven years. The Punjab administration acted decisively after the Air Quality Index (AQI) in Lahore reached a concerning peak of 409 in November.2

Is Agri-residue Burning a Menace for Air Quality &amp; Public Health in Delhi, India?

Skies over Delhi become blurred and visibility is significantly reduced and the air is hefty and causes a burning sensation in the eyes. As every year in November, a thick blanket of smog veils Delhi and its surrounding National Capital Region-NCR of India, which constitute the world’s most polluted megacity. According to a senior pulmonologist and member of the WHO commission on global air pollution and health, patients experiencing breathing problems increase by 30-40 percent every year during October-November. But Delhi’s smog wasn’t always this bad in early winter; it started only about 10-15 years ago. Satellite images show high Aerosol Optical Depth (AOD), as soon as farmers start burning paddy straw and stubble (agri-residue) in agricultural fields, and air quality severely deteriorates. The agri-residue smoke from agricultural areas surrounding Delhi, combined with urban pollution from vehicles, industry, and fireworks from the Diwali festival, increase pollutants to the severe category. Smoke from farm fires after harvest contributed about ⁓ 26-50% of the PM2.5 (tiny particles that damage lungs and can worsen cardiac ailments) to Delhi’s air in November 2023. The average resident of this megacity is on track to lose ⁓ 8 years of life expectancy if high pollution levels persist (EPIC, 2023). Authorities in this smog-ridden capital, even imposed emergency school closures of 7 to 15 days in 2016, 2017 and 2023 to mitigate health issues in the population, who flooded emergency wards at hospitals.