SummaryThis paper presents an alternative approach for predicting the dynamic wind response of tall buildings using artificial neural network (ANN). The ANN model was developed, trained, and validated based on the data generated in the context of Indian Wind Code (IWC), IS 875 (Part 3):2015. According to the IWC, dynamic wind responses can be calculated for a specific configuration of buildings. The dynamic wind loads and their corresponding responses of structures other than the specified configurations in IWC have to be estimated by wind tunnel tests or computational techniques, which are expensive and time intensive. Alternatively, ANN is an efficient and economical computational analysis tool that can be implemented to estimate the dynamic wind response of a building. In this paper, ANN models were developed to predict base shear and base bending moment of a tall building in along‐ and across‐wind direction by giving the input as the configuration of the building, wind velocity, and terrain category. Multilayer perceptron ANN models with back‐propagation training algorithm was adopted. On comparison of results, it was found that the predicted values obtained from the ANN models and the calculated responses acquired using IWC standards are almost similar. Using the best fit model of ANN, an extensive parametric study was performed to predict the dynamic wind response of tall buildings for the configurations on which IWC is silent. Based on the results obtained from this study, design charts are developed for the prediction of dynamic wind response of tall buildings.