The behavior of airport precast concrete pavement (APCP) involving new design and construction concepts was experimentally analyzed under environmental and moving airplane loads, and the long-term performance of the APCP was evaluated using fatigue failure analysis. The strain characteristics and curling behavior of the APCP under environmental loads were comprehensively analyzed. The APCP slabs exhibited a pronounced curling phenomenon similar to conventional concrete pavement slabs. The dynamic response of the APCP subjected to impact loads was analyzed by performing heavy weight deflectometer tests. The test results confirmed that the vertical deformation of the APCP was small and within the typical range of vertical deformation of conventional concrete pavement. The dynamic strain response of the APCP under moving airplane loads was then analyzed and the strain variation during day and night times was compared. The strains during the day were found to be significantly larger than those at night under airplane loads because of the curling phenomenon of the APCP slabs. Finally, the long-term performance of the APCP was evaluated using fatigue failure analysis based on the obtained behavior. Even using the most conservative fatigue failure prediction model, the service life of the APCP was ascertained to be more than 30 years. Based on the overall results of this study, it is concluded that the APCP, which is designed to reduce slab thickness by placing reinforcing bars in the slabs via reinforced concrete structural design, exhibits typical behavior of concrete pavements and can be successfully applied to airport pavement rehabilitation.