The development of artificial intelligence and the introduction of intelligent systems in manufacturing and services are already having a major impact on the relationship between employees and employers: working conditions are changing, the employer’s ability to monitor the performance of their work duties by employees and evaluate the results of their work is expanding. The analysis of the ongoing processes allows us to conclude that in the conditions of Industry 4.0, the further spread of artificial intelligence systems in the world of work is inevitable, which will increase the frequency of human-machine interactions and qualitatively change the production environment. This will be facilitated by reducing the cost of training artificial intelligence and increasing its efficiency, the platformization of the economy, the implementation in practice of the model of smart manufacturing, etc. A further increase in the role of artificial intelligence in the world of work will accompany the transition to the next stage (Industry 5.0), which will affect the actual situation of the employee and the employer, causing the need to make changes to the norms of labour law that consolidate their status as subjects of labour relations.