A theoretical investigation has been made on modulational instability (MI) and dust-acoustic (DA) rogue waves (DARWs) in a four-component dusty plasma medium containing inertial negatively charged massive heavy (light) cold (hot) dust grains as well as super-thermal electrons and non-thermal ions. The reductive perturbation method is used to derive the nonlinear Schrodinger equation, and two types of modes, namely fast and slow DA modes, have been observed. The conditions for the MI and the formation of associated DARWs are found to be significantly modified by the effects of non-thermality of ions (α), super-thermality of electrons (κ), density-ratio of non-thermal ion to cold dust ($${{\mu }_{i}}$$), and mass-ratio of cold dust to hot dust (σ), etc. The implications of our current investigation in space and laboratory plasmas are briefly discussed.