E-mail: janaljubas@yahoo.com Purpose: We investigated pretransplant and posttransplant factors that could influence survival and development of cardiac allograft vasculopathy (CAV) and graft cellular rejection (CR) in heart transplant patients (Pts). Methods: 120 study Pts in the follow-up 10 years, mean age 48,8±13,5. The patient characteristics (age, gender, blood type, diagnosis, pulmonary vascular resistance — PVR), transpulmonary gradient, graft ischemic time and duration of extracorporeal circulation, ECC) and pretransplant comorbidities (diabetes mellitus, chronic renal failure, hypertension, hyperlipidaemia) were analysed. Postransplant complications (postHTx hypertension, chronic renal failure — postHTx-RF, steroid diabetes mellitus — SDM) were also correlated with CAV and mortality, as well as biomarkers such as NT-proBNP and troponin T. Immunosuppressive regimens and cellular rejection were also analyzed. For statistical analysis chi-square test, student t-test and ANOVA were used (SPSS vers.21). Results: Higher transpulmonary gradient (but not PVR) correlated significantly with higher mortality (p=0,003), as well as longer ischemic time (p=0.004) and ECC duration (p=0.043). Proπireni saaeetak / Extended abstract