Background: Improvement of type 2 diabetes occurs independent of weight-loss after bariatric surgery that excludes the proximal small intestine, and is to a major part the result of increased incretin levels. The duodenal-jejunal bypass liner (DJBL) is an endoscopically delivered and removable device creating a duodeno-jejunal bypass thereby mimicking Roux-en-Y and Duodenal-Jejunal Bypass procedures. The DJBL is indicated for the treatment of type 2 diabetes and obesity. Here we report interim results of the ongoing data collection of 26 patients treated by this procedure.