Dumlupinar University Research Articles

Neutrophil-to-lymphocyte ratio in patients with peripheral vertigo: A prospective controlled clinical study

We aimed to investigate the relationship between peripheral vertigo and inflammation by using the neutrophil-to-lymphocyte ratio (NLR) as an inflammatory marker. We recruited 103 patients with peripheral vertigo (71 women, 32 men; mean age, 39.8±14.7years) who presented to the Otolaryngology Department of Dumlupinar University Hospital. Vertigo patients with systemic diseases, neurological disorders, malignancy or any inflammatory disease that could alter the NLR were excluded from the study. We also enrolled 103 age- and sex-matched healthy subjects (controls; 82 women, 21 men; mean age, 36.7±13.5years) who underwent routine checkups in our hospital. The vertigo patients underwent full otolaryngologic and neurologic examinations and audiometric tests to rule out any other pathology causing the peripheral vertigo. NLR was calculated in all subjects and was compared between the patient and control groups. There were no significant differences between the study and control groups in terms of lipid profiles, liver-function tests, white blood cell (WBC) count, hemoglobin level, mean platelet volume, and vitamin B12 and folate levels. The mean NLR was significantly higher in the patients than in the controls (P<0.05). In conclusion, this study, which was the first to investigate the relationship between the NLR and peripheral vertigo, found that the NLR is significantly higher among peripheral vertigo patients than among healthy controls. This result suggests that the NLR is a novel potential marker of stress in peripheral vertigo patients.

ENDOMETRİAL ÖRNEKLEME SONUÇLARIMIZ :744 OLGUNUN ANALİZİ (EVALUATION OF ENDOMETRIAL BIOPSY RESULTS IN OUR CLINIC; ANALYSIS OF 744 CASES)

Amac : Klinigimizde endometrial ornekleme yapilan olgularda, endikasyon ile histopatolojik sonuclar arasindaki iliskinin arastirilmasi. Materyal metod: Klinigimize Ocak 2013- Ocak 2014 tarihleri arasinda basvuran ve gebelik disi herhangibir endikasyonla endometrial ornekleme yapilan 744 olgu retrospektif olarak degerlendirildi. Veriler hastanemiz arsivinden alindi. Endometrial ornekleme endikasyonlari, menometroraji/menoraji, postmenapozal kanama, myom uteri ve servikal polip olarak gruplandirildi. Istatistiksel analiz icin SPSS 13 programi kullanildi. Bulgular : Olgularin yaslari 29 ile 79 arasinda idi. Hastalarin ortalama yaslari 43.6 +/- 8.3 idi. Endometrial ornekleme endikasyonlari sirasiyla menometroraji/menoraji (%87), postmenopozal kanama (%9.5), servikal polip (%1.9), myom uteri (%1.6) idi. Histopatolojik sonuclar ise sirayla proliferatif/sekretuar endometrium (%72.8), endometrial polip (%9.5), basit atipisiz hiperplazi (%7.9), atrofik endometrium (%3.5), endometrit (%3.2), yetersiz materyal (%0.9), endometrium kanseri (%0.8), basit atipili hiperplazi (%0.7), komplex atipili hiperplazi (%0.3), komplex atipisiz hiperplazi (%0.3) idi. Endometrium kanseri gorulme orani postmenapozal kanamasi olan hasta grubunda %5.6 ile diger gruplara oranla anlamli derecede yuksek bulundu. En sik ornekleme endikasyonu menometroraji/menoraji saptanirken, bu olgularda endometrium kanseri sadece 2 (%0.3) olguda saptanmistir. Myom uteri ve servikal polip nedeniyle yapilan endometrial orneklemelerde hic endometrium kanseri gorulmemistir. Sonuc : En sik endometrial ornekleme endikasyonu menoraji/menometroraji iken endometrium kanseri acisindan riskli grubun postmenopozal kanamali olgularin oldugu gosterilmistir. Postmenapozal kanamali hastalarda ciddi endometrial degerlendirme ve ornekleme yapilmaliyken myoma uteri nedeniyle histerektomi planan hastalarda operasyon oncesi endometrial orneklemenin gerekli bulunmamistir. Fakat servikal polip olgularinda endometriumunun degerlendirilmesinin gerektigi sonucuna varilmistir. Anahtar kelimeler : endometrial ornekleme, anormal uterin kanama, endometrium kanseri ABSTRACT Aims : to evaluate indications and histopathological diagnoses of endometrial samplings in our clinic. Materials-Methods: Seven hundred and fourty four subjects who required endometrial biopsy to be taken for any indication other than pregnancy between January 2013 and January 2014 were included in the study. Data collected retrospectively from Dumlupinar University Evliya Celebi Training and Research Hospital computer database and pathology clinic. Statistical analysis of data was performed using SPSS for Windows package programme. Results : Mean age of the subjects was 43.6 ± 8.3. Indications of endometrial sampling were menorrhagia/menometrorrhagia (87%), myoma uteri (1.6%), postmenopausal bleeding (9.5%), servical polyp (1.9%). Histopathologic diagnoses were as follows: secretory/proliferative endometrium in 72.8%, atrophic endometrium in 3.5%, simple atypical endometrial hyperplasia in 0.7%, simple typical endometrial hyperplasia in 7.9%, complex atypical endometrial hyperplasia in 0.3%, complex typical endometrial hyperplasia in 0.3%, atrophic endometrium in 3.5%, endometrium cancer in 0.8%, and endometrial polyp in 9.5%. Insufficient sampling material was reported in 0.9%. Endometrium cancer was detected in 5.6% of postmenopausal group. Conclusions : Our results emphasize that endometrial sampling is warranted especially in peri/postmenopausal women with abnormal uterine bleeding. Keywords : endometrial sampling, abnormal uterine bleeding, endometrial cancer

May dental extraction trigger subacute thyroiditis?

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Incidence of rotavirus and adenovirus 40/41 in children and infants

Abstract Rotavirus is most common agent responsible for acute gastroenteritis in Turkey as its in the world. The purpose of this study is the determination of Rotavirus and Adenovirus incidence in children between ages 0 and 18 that consulted to Dumlupinar University Faculty of Medicine - Evliya Celebi Research and Implementation Hospital with diarrhea between May 2012 and February 2013. The recordings of 1082 stool samples of patients consulted to our hospital with diarrhea or children hospitalized for some other reason and developed diarrhea after admission to hospital during the period of May 2012 -February 2013 were scanned retrospectively. Stool samples were tested for Rotavirus and Adenovirus 40/41 antigenes using ACON - The One Step Rotavirus and Adenovirus Combo Test Device which is a rapid chromatographic immunassay for the qualitative detection of rotavirus and adenovirus in human feces specimens. Rotavirus antigens were detected in 141 (13%) and Adenovirus 40/41 antigens were detected in 25 (2%) of all specimens. Rotavirus positivity was detected to be highest in children between 0 and 2 years old and during winter season. Rotavirus is most common agent responsible for acute gastroenteritis in children under 2 years old and must be investigated especially during winter and spring seasons. Keywords: Rotavirus, adenovirus, incidence DOI: 10.12973/ejms.2014.104p

Candidate Mother Tongue Teachers’ Perceptions on Speech Skills

Candidate mother tongue teachers have a class on elocution in their third year at university. However it is necessary to determine how candidate teachers feel about their speech skills, what they think of this class, and their expectations from this class. In this research, the researchers worked with 50 candidate mother tongue teachers from Dumlupinar University. Data was collected with open-ended surveys, and analyzed through content analysis. Based on the results of the research, the researchers tried to determine the participants' perceptions of themselves and the class. The researchers found out that the participants do not generally consider themselves to be eloquent speakers. A large majority of them did not take any elocution classes or anything simila r prior to coming to university. Participants are aware of certain speech defects they have. These mainly include the use of local dialects, nervousness, and pronunciation problems. The main factors which contribute to their overall poor speech are the lack of self esteem and not being well informed in the subject matter.

Department of Primary Education Students’ Opinions Regarding the Necessity of Graduate Education

Today, increa sing importance of knowledge and not considering teacher as the only source of knowledge, changes the role of teacher dramatically. Teachers need to improve themselves continuously to match the demands of the roles future brings them. To improve oneself as a teacher requires pursuing life-long learning as a principle, and attaining professional skills like providing more student-centered educational cond itions and environments to students and contributing to their multi-dimensional development. Higher education, especially graduate education has a great role to help the teacher with this task. The aim of this research is to obtain primary teachers' opinions regarding the necessity of graduate education. The sample of the research consist s of 82 pre- service teachers who were enrolled to Dumlupinar University department of primary education during t he 2010- 2011 academic year. The research using the survey analysis methodology is descriptive in nature. Dat a were collected through the survey, as developed by the researcher. Based on the results, 43.9% of the candidates believe graduate education is somewhat necessary while 35.4% believe the reason for pursuing a graduate education is to continue professional development and 45.1% of them would like to pursue graduate education. On the other hand, 48.8% of the candidates want to pursue graduate education to develop their higher-order thinking skills and 45.1% of them want to receive graduate education to obtain old/new knowledge and skills in their own field. These results are important in terms of understanding the base of the criteria which primary teacher candidates' point of views are being shaped by regarding graduate education as well as measure the level of their desire to pur sue graduate education.

Investigation of Cryptosporidiosis by Serologic and Microscopic Method and Examination of Tap Water Samples for Oocysts

This study surveyed the prevalence of cryptosporidiosis in patients who were treated in Dumlupinar University Medical Faculty Hospital for various gastrointestinal complaints such as abdominal pain, nausea, vomiting and diarrhea. Water samples were taken from various homes and fountains. Stool samples were investigated for the presence of oocysts with Kinyoun's carbol fuchsin staining method. After miscroscopic analysis, samples were preserved. These frozen samples were thawed promptly for antigenic diagnosis (Ridascreen® , R-Biopharm AG, Darmstadt Germany). Thirty units of ten-liter water samples were filtered by a vacuum pump (45 μm). Filtered materials were stained through Kinyoun's carbol fuchsin staining method and examined. Stool samples taken from a total of 146 patients were examined for oocyst presence and 4 individuals (2.7 percent) were found to be positive. Elisa tests of the same samples proved 5 individuals (3.4 percent) as positive for specific antigens. Only one water sample was diagnosed as positive for oocysts. Cryptosporidiosis was found to be present in 3.4 percent of this group of people, and the distribution of infection among subjects was understood to be not statistically meaningful by gender, age and identification methods (p > 0.05). Finding of oocysts in only one sample out of 30 (3.3%) led to a need for reconsideration of other causal factors in the epidemiology.

Mechanical Properties of Nanocrystalline Tetragonal Zirconia Stabilized with CaO, MgO and Y2O3

Stabilized with CaO, MgO and Y2O3 O. Sahina,∗, . Demirkol, H. Gocmez, M. Tuncer, H. Ali Cetinkara, H. Salih Guder, E. Sahin and A. R za Tuncdemir Department of Physics, Art and Science Faculty, Micro/Nanomechanic Characterization Laboratory Mustafa Kemal University, Hatay, Turkey Department of Ceramic Engineering, Dumlupinar University, Kutahya, Turkey Department of Prosthetic Dentistry, Dentistry Faculty, Mustafa Kemal University, Hatay, Turkey

Hardness Behavior of Alumina-Zirconia Nanocomposites Synthesized by Gel Process

Synthesized by Gel Process O. Sahina,∗, A. Hasde, H. Gocmez, M. Tuncer, H. Ali Cetinkara, H. Salih Guder, E. Sahin and A. R za Tuncdemir Department of Physics, Art and Science Faculty, Micro/Nanomechanic Characterization Laboratory Mustafa Kemal University, Hatay, Turkey Department of Ceramic Engineering, Dumlupinar University, Kutahya, Turkey Department of Prosthetic Dentistry, Dentistry Faculty, Mustafa Kemal University, Hatay, Turkey

Computational Intelligence in Civil and Hydraulic Engineering

1 College of Computer Science & Technology, Zhejiang University of Technology, Hangzhou 310023, China 2 Faculty of Infrastructure Engineering, Dalian University of Technology, Dalian 116024, China 3Marand Faculty of Engineering, University of Tabriz, Tabriz 51368, Iran 4Department of Civil, Construction, and Environmental Engineering, Iowa State University, IA 50011, USA 5 Computer Engineering Department, Dumlupinar University, 43100 Kutahya, Turkey

Examination of Socialization Levels of University Students Engaging in Individual and Team Sports

The objective of this study is to examine socialization levels of university students engaging in individual and team sports.587 university students in total including 248 girls and 339 boys receiving education in various faculties and graduate schools of Dumlupinar University, Inonu University, Gazi University and 19 Mayis University constitute the research group. To achieve study objective, the socialization scale developed by Sahan (2007) was used.Significance was extracted P<0.05 by employing The Kolmogorov-Smirnov test and two-way ANOVA test in solution and interpretation of data. SPSS (Statistical package for social sciences) package software was employed in evaluation of data and finding the calculated values. As a result of this study, students, who are engaged in team sports, have higher socialization levels than students performing in individual sports. Besides, it was found that department and branch variable has an influence on socialization levels of students.

A new measurement method for determination of low back pain

The patient's low back pain can be determined using the visual analog scale (VAS) as subjective methods. This study aims to design a device used in evaluating low back pain objectively, by measuring skin resistance. To test the developed system, 8 low back pain (experimental group) and 8 healthy (control group) subjects were admitted in Dumlupinar University, Medical Faculty, Physical Therapy and Rehabilitation services. The skin resistance of all the subjects has been measured from their back using both the DC and the AC supplies. The skin resistance of the experimental group before the treatment and at the end of 15 days of the treatment was measured. The results of the treatment of the experimental group before and after treatment have been found to be statistically significant (p < 0.05). The measured skin resistance values were found to be statistically significant, when compared to the control and the experimental groups (p < 0.05). As a result of these findings, the developed system can be used to objectively determine low back pain by measuring skin resistance. Key words: Skin resistance, low back pain, visual analog scale, objective measurement.

Prevalence of dysmenorrhea and its effect on quality of life among a group of female university students

The objective was to evaluate the prevalence of dysmenorrhea and determine its effect on health-related quality of life (HRQoL) among a group of female university students. This cross-sectional study was conducted between 15 March and 15 April 2009 at Dumlupinar University, Kutahya, Health High School, Western Turkey. The study group included 623 female students. The severity of dysmenorrhea was determined with a 10-point visual analog scale. The Short Form-36 (SF-36) form was used to determinate HRQoL. Chi-square test, Student's t test, and logistic regression and variance analyses (ANOVA) were used for statistical analyses. The average age of the study group was 20.8 ± 1.8 years (range 17–30). Prevalence of dysmenorrhea was found to be 72.7% and was significantly higher in coffee consumers, females with menstrual bleeding duration ≥7 days, and those who had a positive family history of dysmenorrhea when compared to the others (P < 0.05, for each one). By multivariate analysis, coffee consumption (OR 2.084), menstrual bleeding duration ≥7 days (OR 1.590), and positive family history of dysmenorrhea (OR 3.043) were important risk factors for dysmenorrhea. Except for social functioning, role–emotional, and mental health domains, the SF-36 points received from the other domains were higher in females with dysmenorrhea (for each one P < 0.05). With the exception of the scores received from physical functioning and role–emotional domains, the scores received from the other domains of the SF-36 scale showed a decrease with increasing severity of dysmenorrhea (P < 0.05, for each one). Dysmenorrhea is a common health problem, having negative effects on the HRQoL among university female students.

Technoeconomic analysis of electricity generation from wind energy in Kutahya, Turkey

Conventional energy usage has various environmental effects that cause global warming. Renewable energy sources are thus more favorable because they have nearly zero emission. Wind energy, among the various renewable sources, finds increasing usage, concurrent with developing technology. In addition, wind is an infinite energy source. In this study, the electricity-generation ability of Kutahya has been investigated. With this aim, wind data, from the measurement station located on Bunelek Hill, Kutahya, have been collected for a period of 36 months (July 2001–June 2004). From the collected data, the electricity generated has been calculated for different types of wind turbines. The calculations have been based on the electricity requirement of the main campus of the Dumlupinar University. Finally, the economic evaluation has been analyzed using life-cycle cost analysis. For the analysis of the economical aspects, the social and CO2 costs have also been taken into account.

Bilgi Liderliğinin Verimlilik Üzerine Etkisi: Sağlık Sektöründe Bir Araştırma

Bilgiyi sistematik bir biçimde yöneten ve katma değer elde eden işletmeler rekabet avantajı sağlayacak ve rekabeti karşılayacaktır. İşletmelerde bilginin elde edilmesi, saklanması, paylaşılması ve kullanılmasına, diğer bir deyişle bilgi yönetiminin etkin ve başarılı bir şekilde gerçekleşmesine etki eden faktörler bulunmaktadır. Araştırmanın temel amacı küresel ekonomide bilgi liderliğinin verimlilik üzerine etkisinin araştırılmasıdır. Çalışma, bilgiyi üretme ve kullanmada en başarılı örnekleri sergileyen araştırma hastanelerinde görev yapan yöneticiler üzerinde gerçekleştirilmiştir. Araştırmanın kapsamına Afyon Kocatepe Üniversitesi, Isparta Süleyman Demirel Üniversitesi, Konya Selçuk Üniversitesi, Kütahya Dumlupınar Üniversitesi ve Eskişehir Osmangazi Üniversitesi hastanelerinde görev yapan başhekimler, başhekim yardımcıları, hastane müdürleri, müdür yardımcıları, başhemşireler ve başhemşire yardımcılarından oluşan toplam 120 yönetici dahil edilmiştir. Bu araştırmanın sonucunda ise bilgi liderliğinin verimlilik üzerine olumlu etkisi olduğu sonucuna varılmıştır.

Does long-term talc exposure have a carcinogenic effect on the female genital system of rats? An experimental pilot study

In several studies, the prolonged exposure to talc has been associated with development of ovarian cancer. However, some studies have advocated contrary views. The present study aims to investigate histopathological changes and whether long-term talc exposure is associated with potential carcinogenic effects on the female genital organs of rats. The present study was conducted at Dumlupinar University Medical Faculty and a total of 28 Sprague-Dawley rats were included. The experimental animals were allocated into four groups having seven rats each. Groups 1 and 2 served as controls, where the rats in Group 1 did not receive any intervention and Group 2 received intravaginal saline. Groups 3 and 4 received intravaginal or perineal talc application, respectively. Talc was applied for 3 months on a daily basis. Histopathological changes in the peritoneum and female genital system were evaluated. For statistical analyses, Fisher's exact test was carried out using SPSS. In both the groups exposed to talc (Groups 3 and 4), evidence of foreign body reaction and infection, along with an increase in inflammatory cells, were found in all the genital tissues. Genital infection was observed in 12 rats in the study group and 2 rats in the control group. Neoplastic change was not found. However, there was an increase in the number of follicles in animals exposed to talc. No peritoneal change was observed. In the groups not exposed to talc, similar infectious findings were found, but there was a statistically significant difference between the groups (Groups 1 and 2 vs. Groups 3 and 4, P > 0.05). Neoplastic change was also not observed in these groups. Four groups were compared in terms of neoplastic effects and infections. In Groups 1, 5 rats were normal, two developed vulvovaginitis and endometritis with overinfection (in both ovaries), and one developed salpingitis (in both fallopian tubes), that is, infection was found in a total of two rats. In Group 2, only one experimental animal had endometritis. All the animals in Groups 3 and 4 developed infections. Talc has unfavorable effects on the female genital system. However, this effect is in the form of foreign body reaction and infection, rather than being neoplastic.

Dumlupınar Üniversitesi Tıp Fakültesi Hastalarında Entamoeba histolytica Prevalansı

Dumlupınar Üniversitesi Tıp Fakültesi Hastalarında Entamoeba histolytica Prevalansı

A novel stenting technique in endoscopic dacryocystorhinostomy

The objective of our study was to evaluate in a prospective noncomparative case series, the clinical efficacy and the results of modified T-tube insertion instead of silicone tube in endoscopic dacryocystorhinostomy (EDCR). Following ophthalmologic examinations, 22 patients (16 female, 6 male) suffering from recurrent chronic epiphora with postsaccal stenosis for whom DCR was indicated, underwent EDCR at Dumlupinar University Hospital by an otorhinolaryngologist and an ophthalmologist between the years 2006 and 2007. Instead of inserting a classic silicone tube passed through canaliculi and knotted inside the nose, a modified T-tube was used, without passing it through punctum, and was placed to stoma with a less traumatic endonasal endoscopic technique. The medial wall of the sac was incised vertically and the T-tube was placed horizontal to the incision. Postoperatively, the patients were evaluated by endoscopic controls in the first, third, sixth, and twelfth months to evaluate T-tube localization and rhinostomy opening site. The success was defined as resolution of epiphora with patent ostium after evaluation by irrigation and nasal endoscopy. Eighteen patients (82%) showed complete resolution of epiphora at 12-months of follow-up. Re-stenosis was observed only in four cases, one in the sixth and the other in the ninth postoperative months. Granulation tissue formation near the rhinostomy site was seen in one patient, which did not cause any functional problem. The success rate was calculated as 82%. We conclude that modified T-tube placement in EDCR seems to be a practical and less traumatic technique. This is also a cheaper method besides being less traumatic and easier to perform than canalicular stenting. It can be considered as a useful alternative to the classic silicon tubes in cases of epiphora resulting from the postsaccal stenosis.

The effects of biodiesel usage on the components of an engine

In this paper, the research results obtained on the influences of biodiesel on the components of an engine are presented. The study was carried out at the Dumlupinar University in Turkey. Biodiesel has been an alternative fuel for diesel engines since 1900s. However, the use of biodiesel has recently been increasing owing to indelible increase in petroleum price and consumption. Furthermore, the efforts for the environmental protection have been increasing all around the world. Many researches on biodiesel that have concerned engine gas emissions and engine performances have been carried out so far. However, this work was realised to consider the effects of biodiesel on engine components at real time and long-term conditions.

Treatment of White Coat Hypertension With Metformin

White coat hypertension (WCH) is most likely a disorder associated with metabolic syndrome. The study was performed at the Internal Medicine Polyclinic of Dumlupinar University on routine check-up patients. WCH cases who were overweight or obese and desiring weight loss were divided into two subgroups according to whether they preferred to achieve weight loss by medication or diet therapy. The study included 324 cases (204 females) with WCH, 45 of whom were in normal weight range. Therefore, 86.1% (279) of cases with WCH were either overweight or obese, and 41.3% (134) of all WCH cases had dyslipidemia. Twenty-five cases (14.7%) stopped metformin therapy due to excessive anorexia. At the end of a 6-month period, there were highly significant differences between the two groups with respect to the prevalences of resolved WCH, hyperbetalipoproteinemia, hypertriglyceridemia, dyslipidemia, overweight and obesity, and decreased fasting plasma glucose below 110 mg/dL (P < 0.001 for all). Due to gradually increased prevalences of impaired glucose tolerance, type 2 diabetes mellitus, dyslipidemia, excess body weight, and obesity-like disorders from sustained normotension towards WCH and hypertension (HT) cases, and very high prevalences of excess weight and dyslipidemia in the WCH group, WCH may be an associated disorder of metabolic syndrome rather than just being a predisposing factor of atherosclerosis or HT alone. Thus, the management of WCH should not focus solely on the regulation of blood pressure with antihypertensive medications, but rather on the prevention of future excess weight and various associated disorders, and metformin alone is an effective therapeutic option, most likely due to its powerful inhibitory effect on appetite.