We have studied the interparticle force between colloidal particles with three different types of defects in nematic liquid crystal by dual-beam optical tweezers. The force between a dipole (D)- and a Saturn-ring (S)-type particle at large interparticle distance R is proportional to R(-4.95±0.05). The force between a D- and a planar (P)-type particle and that between an S- and a P-type particle are, respectively, proportional to R(-5.04±0.08) and R(-5.78±0.13). The observed dependence of the interparticle force on R at large R is in agreement with that predicted by electrostatic analogy. The topological quadrupole moments for S and P particles are evaluated from experimental data. We have also studied the force curves in oblique arrangement against the far-field director for respective pairs. The experimental force curves at large R quantitatively agree with those predicted by electrostatic analogy, but they always become attractive at small R due to the reorientation and deformation of defects. The force profiles for the S-P pair are also compared with those obtained by the recent numerical simulation.