Driver Of Growth Research Articles

Seasonal investigation of ultrafine-particle organic composition in an eastern Amazonian rainforest

Abstract. Reports on the composition of ultrafine particles (<100 nm in diameter) in the Amazon are scarce, due in part to the fact that new-particle formation has rarely been observed near ground level. Ultrafine particles near the surface have nevertheless been observed, leaving open questions regarding the sources and chemistry of their formation and growth, particularly as these vary across seasons. Here, we present measurements of the composition of ultrafine particles collected in the Tapajós National Forest (2.857° S, 54.959° W) during three different seasonal periods: 10–30 September 2016 (SEP), 18 November–23 December 2016 (DEC), and 22 May–21 June 2017 (JUN). Size-selected (5–70 nm) particles were collected daily (for 22 h each day) using an offline sampler. Samples collected during the three time periods were compiled and analyzed using liquid chromatography coupled with Orbitrap high-resolution mass spectrometry. Our findings suggest a sustained influence of isoprene organosulfate chemistry on ultrafine particles from the different periods. We present chemical evidence that indicates that biological-spore fragmentation impacted ultrafine-particle composition during the late wet season (JUN), while chemical markers for biomass burning and secondary chemistry peaked during the dry season (SEP and DEC). Higher oxidation states and degrees of unsaturation were observed for organics in the dry season (SEP and DEC), suggesting greater extents of aerosol aging. Finally, applying a volatility parameterization to the observed compounds suggests that organic sulfur species are likely key drivers of new-particle growth in the region due to their low volatility compared to other species.

Exploring the Tourism and Economic Growth Relationship in Vietnam: A Cointegration Analysis with Model-Specific Structural Breaks

In this study, we present a comprehensive analysis to examine the resilience of tourism in Vietnam since the Doi Moi period. Using an augmented Solow framework, data from 1986 to 2020, and the ARDL approach, we estimate the long-run and short-run effects, whilst accounting for model-specific structural breaks. To provide stronger validation and robustness of the results, we estimate eight models under four cases. We start with the base model, which includes tourism and capital (in per worker terms), and then augment it with factors that are carefully identified from the literature. The additional factors include urbanisation, financial development, trade openness, foreign direct investment (FDI), information and communication technology (ICT), and natural resources. We find that capital accumulation and tourism (in per worker terms) remain positive drivers of growth in all the estimations. Results from alternative models also highlight the pro-growth effects of urbanisation, financial development, and trade openness. A positive association between carbon emissions and economic growth is also noted, indicating the existing production–consumption setup, the pace of environmental harvesting, and the weak decoupling effects that could lead to negative externality in the long run. Factors like technology, natural resource rents, and FDI show negative effects on growth as well. Moreover, by examining the causality dynamics, the study further contributes to broader policy discussion. Hence, policies targeted to promote the growth process, and the advancement of the economy, should continue supporting capital accumulation, tourism development, urbanisation, financial development, and international trade. However, future economic policies should cautiously address emissions, natural resource use, and re-evaluate the gains from foreign direct investment (FDI) to ensure growth remains sustainable. With tourism and capital accumulation at the core of this study, the findings of this study are intended to generate deeper policy discussions on resource allocations and the need to harness and/or rely on contemporary sources of growth to promote the sustainable development of Vietnam.

Spatial Dynamics and Drivers of Urban Growth in Thua Thien Hue Province, Vietnam: Insights for Urban Sustainability in the Global South

Investigating the historical patterns of urban growth and their drivers is crucial to informing sustainable urban planning policies, especially in cities of the Global South. In Vietnam, most studies focus primarily on city extents, offering little insight into urban growth across various provinces. This study, therefore, combined categorical land use and land cover change detection, Random Forest classification and expert interviews to quantify the urban growth between 2000 and 2020, assess urban encroachment upon other land uses, and identify key drivers shaping this growth in Thua Thien Hue province. Findings show that the urban land areas were 27.94 km2, 82.97 km2, and 209.80 km2 in 2000, 2010, and 2020, respectively. Urban encroachment upon other land use types, especially cropland, barren land, rice paddies, shrubs, and forests, was observed in these periods. Additionally, accessibility to built-up areas, DEM, proximity to rice paddies, slope, proximity to street roads, accessibility to social areas, and proximity to cropland are the major spatial drivers of urban growth in the province. The study concludes that rapid urban expansion is evident in the province at the expense of other land use types, especially agricultural land use types, which may impact food security and livelihoods in the province.

The chemokine CX3CL1 promotes intraperitoneal tumour growth despite enhanced T-cell recruitment in ovarian cancer.

T-cell recruiting chemokines are required for a successful immune intervention in ovarian cancer, and also for the efficacy of modern anticancer agents such as PARP inhibitors. The chemokine CX3CL1 recruits tumour-suppressive T-cells into solid tumours, but also mediates cell-cell adhesions, e.g. of tumour cells, through its membrane-bound form. So far, its role in ovarian cancer has only been rudimentarily addressed. We show that high CX3CL1 expression significantly correlates with worsened survival in human high-grade serous ovarian cancer (n=219). In preclinical ovarian cancer, CX3CL1 plays a dual role, as it enhances the adaptive anti-tumour response, but overall still promotes tumour growth, the latter as a feature of the intraperitoneal environment. Moreover, PARP inhibitors are able to increase CX3CL1 release from human ovarian cancer cells. Collectively, our study shows that CX3CL1 is a driver of intraperitoneal tumour growth in ovarian cancer, a feature that may compromise the anticancer effect of CX3CL1-inducing PARP inhibitors.

Exploring the nexus of migration dynamics and urban expansion: key drivers of horizontal spatial growth in Woldia Township, Ethiopia

Ethiopia remains one of the least urbanized countries globally, although many of its urban centers, including Woldia, the capital of the North Wollo Zone, are undergoing rapid growth. Woldia has recently faced significant urban challenges due to its expanding horizontal growth. One of the major issues associated with this growth is the increasing demand for land and space, driven by population pressure, largely attributed to migration. This migration has led to the annexation of agricultural land at the rural periphery, further contributing to the town’s horizontal expansion. This study aims to explore the key drivers behind the horizontal growth of Woldia, particularly in its peripheral areas. Data were collected through a structured questionnaire administered to a randomly selected sample of 395 respondents, complemented by key informant interviews and secondary data sources. Both qualitative and quantitative analytical methods were employed. The findings indicate that poor social services and poverty in migrants’ areas of origin are the primary push factors. Conversely, improved social infrastructure and job opportunities at the destination are the main pull factors. Consequently, the influx of migrants has resulted in significant pressure on peri-urban areas, where housing availability and accessibility remain limited. The study recommends that local government officials and urban planners enhance their understanding of migration dynamics to effectively manage the town’s spatial expansion and address the challenges of accommodating a growing population.

Characterization of a pleomorphic rhabdomyosarcoma cell line

Pleomorphic rhabdomyosarcoma (PRMS) is an extremely rare soft tissue tumor with dismal prognosis that has a higher incidence in adults compared to the other RMS subtypes. The unique PRMS cell line BH1522 was established from a pleural effusion of a lung metastasis and the characteristics of this cell line were compared to two embryonal type RMS (ERMS) cell lines. The affected patient had been treated by surgery, several cycles of chemotherapy and thoracoscopy of the lung metastases. Chemosensitivity of the PRMS cell lines was checked using cytotoxicity assays and oncogene-related and phosphoproteins by Western blot arrays. The BH1522 cell line proved to be chemosensitive to conventional chemotherapeutics and the Son of Sevenless 1 homolog (SOS1) inhibitor BAY-293 that inhibited proliferation and suppressed MYC activity. Results of the novel functional BH1522 tests corroborate published tumor sequencing data that demonstrated alterations in receptor tyrosine kinase/MAPK, PI3K/AKT and mutated p53 as suspected drivers of malignant growth.

Digital Financial Transactions and Business Performance: The Role of Mobile Money in Ghana’s SME Sector: Evidence from the Sunyani Municipality

This study examines the role of mobile money (MM) transactions in enhancing the performance of small and medium enterprises (SMEs) in the Sunyani Municipality, Ghana. While previous studies have explored the impact of mobile money on various aspects of economic development, limited research has specifically examined its direct impact on SME performance in the Ghanaian context. A purposive sampling technique was employed to select 120 SMEs from various sectors, including retail, electronics, and services. Data collected through structured questionnaires were analyzed using Statistical Package for Social Sciences (SPSS) version 20 and STATA version 13, focusing on key variables such as sales revenue, frequency of mobile money transactions, and business characteristics. The results reveal a significant positive relationship between the frequency of MM transactions and sales revenue (r = 0.45). Specifically, for each additional MM transaction, sales revenue increased by GHC 500, and for every additional GHC transacted, sales revenue increased by GHC 1.50. The amount transacted via MM showed a stronger correlation with sales revenue (r = 0.60), emphasizing that higher transaction volumes drive business growth. While business age and workforce size positively impacted revenue, their influence was weaker compared to MM usage. The regression analysis further confirmed the critical role of mobile money, with MM transaction frequency and amount being the most significant predictors of sales revenue. The findings suggest that wider adoption of mobile money services could enhance operational efficiency, expand market reach, and improve financial performance, positioning MM as a key driver of SME growth in emerging markets. This study contributes to the growing body of literature on digital financial inclusion and business development, offering practical insights for policymakers and SME owners. The study covers only SMEs in Sunyani Municipality, and thus results may be limited to the generalization to other regions with different socio-economic characteristics. Based on the findings, the study recommends that promotion of the use of mobile money by SMEs be stepped up through targeted financial literacy and awareness creation directed at explaining the utility and profitability of the instrument.

Environmental impacts of urban growth and land use changes in tropical cities

Urban centers across the globe are undergoing rapid land use changes due to population growth, economic development, and urbanization. These changes have a profound impact on environmental dynamics and urban livelihoods. This study investigates land use changes and their environmental implications on urban livelihoods in Iwo, Nigeria. The research explores the patterns and drivers of land use changes over the past four decades and evaluates their effects on environmental quality and urban livelihoods. A combination of remote sensing and survey methods was employed. Landsat images from 1982 to 2023 were analyzed using supervised classification techniques to map changes in land cover categories such as built-up areas, vegetation, farmland, bare land, and water bodies. Additionally, a survey was conducted with 550 residents, selected through simple random sampling, to identify the key drivers of urban expansion from the residents’ perspectives. Descriptive analysis revealed that most respondents had lived in Iwo for over 30 years, with many engaged in farming, trading, and civil service. Factor analysis was used to identify significant variables driving urban growth. The results indicate a substantial increase in built-up areas, from 9.30 km2 in 1982 to 30.69 km2 in 2023, alongside a significant decrease in vegetation cover. Farmland area showed an increasing trend, while bare land decreased. Key drivers of urban growth identified include religious activities, availability of land resources, small-scale businesses, government initiatives, and educational institutions. The environmental implications include deforestation, reduced green spaces, increased surface runoff, and pollution, which affect air quality, water resources, and biodiversity. This study highlights the importance of sustainable urban planning to balance growth with environmental preservation and social equity. The implementation of green infrastructure, effective waste management, and comprehensive urban planning policies is crucial to enhancing resilience and quality of life in Iwo.

Unravelling connections: energy, economic growth, and decoupling through a historical lens

ABSTRACT Decoupling pervades environmental policy, yet its extent remains a topic of debate. Decoupling suggests that economic growth can detach from resources, energy, and impacts through technology and efficiency. However, biophysical theory asserts that the primary driver of growth has been the expansion of energy supply. We contribute to the debate by highlighting a crucial yet often overlooked distinction between tangible and abstract phenomena. This distinction is important because, fundamentally, physical effects must have physical causes. A challenge lies in establishing a causal relationship between energy and economy given the intermediary role of money as a social technology. Both decoupling and biophysical frameworks grapple with this challenge, yet neither provides a definitive resolution. Biophysical theory emphasises physical processes but struggles to incorporate money into a causal schema, while decoupling prioritises monetary factors but fails to explain the critical role of energy and resources. To bridge this disparity, we present a causal model that clarifies the connection between money and the tangible economy. We trace the historical evolution of abstract value through the development of private property, coinage, and modern currency, illustrating how these constructs became intertwined with energy supply and storage. Through this exploration, we offer a novel perspective on decoupling.

The Homeobox Transcription Factor NKX3.1 Displays an Oncogenic Role in Castration-Resistant Prostate Cancer Cells.

Prostate cancer (PCa) is the second leading cause of cancer-related death in men. The increase in incidence rates of more advanced and aggressive forms of the disease year-to-year fuels urgency to find new therapeutic interventions and bolster already established ones. PCa is a uniquely targetable disease in that it is fueled by male hormones (androgens) that drive tumorigenesis via the androgen receptor or AR. Current standard-of-care therapies directly target AR and its aberrant signaling axis but resistance to these therapies commonly arises, and the mechanisms behind the onset of therapy-resistance are still elusive. Research has shown that even with resistant disease, AR remains the main driver of growth and survival of PCa, and AR target genes and cofactors may help mediate resistance to therapy. Here, we focused on a homeobox transcription factor that exhibits a close relationship with AR-NKX3.1. Though NKX3.1 is traditionally thought of as a tumor suppressor, it has been previously reported to promote cancer cell survival by cooperating with AR. The role of NKX3.1 as a tumor suppressor perhaps in early-stage disease also contradicts its profile as a diagnostic biomarker for advanced prostate cancer. We investigated the physical interaction between NKX3.1 and AR, a modulated NKX3.1 expression in prostate cancer cells via overexpression and knockdown and assayed subsequent viability and downstream target gene expression. We find that the expression of NKX3.1 is maintained in advanced PCa, and it is often elevated because of aberrant AR activity. Transient knockdown experiments across various PCa cell line models reveal NKX3.1 expression is necessary for survival. Similarly, stable overexpression of NKX3.1 in PCa cell lines reveals an androgen insensitive phenotype, suggesting NKX3.1 is sufficient to promote growth in the absence of an AR ligand. Our work provides new insight into NKX3.1's oncogenic influence on PCa and the molecular interplay of these transcription factors in models of late-stage prostate cancer.

Drivers of Green Growth: Roles of Innovation and Fragility

Drivers of Green Growth: Roles of Innovation and Fragility

Halogen Emissions from Coal-Fired Power Plants in China: Evolutions, Driving Forces, and Future Trends.

Atmospheric halogens, including fluorine (F), chlorine (Cl), bromine (Br), and iodine(I), significantly impact atmospheric chemistry and climate change. Containing all types of halogens, coal fired power plants (CFPPs) are among the major anthropogenic sources of atmospheric halogens. However, comprehensive estimates of halogen emissions from CFPPs in China remain limited, despite significant advancements in scale and pollution control. This study developed a detailed emissions inventory for all halogens from CFPPs using multisource data and the mass balance method, analyzing their spatiotemporal variations, driving forces, and future trends under climate goals. Results showed fluctuating halogen emissions from 2018 to 2022, with F, Cl, Br, and I reaching 6,875.7 t, 24,872.4 t, 1,127.9 t, and 476.7 t in 2022, respectively. Emissions were predominately concentrated in key coal resource areas and high-energy-consuming regions. Increased coal consumption was the primary driver of emissions growth, while improvements in pollution control and power generation technology contributed to reductions. Under air pollution control and climate goals, halogen emissions are expected to peak before 2030 and decline rapidly thereafter, with near-elimination by 2050. Combining strict air pollutants and carbon control technologies would offer the greatest reduction potential.

Fine resolution satellite sea surface temperatures capture the conditions experienced by corals at monthly but not daily timescales

Abstract Water temperature is a strong driver of growth, survival, and local adaptation in corals, but our knowledge of the temperatures experienced by corals on reefs worldwide remains limited. While in situ temperature loggers can provide high quality data, they are relatively expensive to place and retrieve. Alternatively, remotely sensed sea surface temperature data are globally available but may be a biased representation of the temperatures experienced by corals. Here, we compared data from 314 temperature loggers on coral reefs to the ~ 1 km2 resolution remotely sensed Multi-scale Ultra-high Resolution Sea Surface Temperature (MUR) product from NASA. We found good agreement (Pearson’s r = 0.95) between maximum monthly mean temperatures calculated from remote and in situ data, with 84% of temperatures within 0.5 °C of each other. However, remotely sensed temperature did not effectively capture sub-diel temperature fluctuations and the highest peak temperatures that may be most dangerous for corals. Predictions of in situ temperatures were significantly but weakly improved by a consideration of reef geomorphology. Ultimately, we found that remotely sensed temperatures can accurately represent the monthly conditions experienced by most corals but should be used with caution at finer temporal scales.

ANALISIS EKONOMI KREATIF DAN PENGGUNAAN TEKNOLOGI DIGITAL STUDI TENTANG TRANSFORMASI DAN PELUANG PERTUMBUHAN BISNIS

This study aims to examine the development of the creative economy and the adoption of digital technology through a qualitative approach and bibliometric analysis. Data collection was carried out by reviewing literature published between 2018 and 2023 to ensure the relevance and timeliness of the information. The analysis method used VOSviewer software to identify trends and patterns in the literature and map out research areas that require further exploration. The findings show that, although there is a close connection between the creative economy, technology, and digital economy, the research cluster covering these four topics is relatively smaller compared to other topics, indicating significant research gaps. The study identifies that policies accelerating digital transformation and the development of the creative sector in Indonesia can be key drivers of creative economy growth. Furthermore, digital transformation in Indonesia's economy holds significant potential despite challenges related to technological disparities and labor absorption. This research also highlights the importance of digital infrastructure and the enhancement of human resource quality to support digital economic growth. These findings provide valuable insights for researchers and practitioners to further explore under-discussed topics and offer a strong foundation for future research on the role of the creative economy and technology in creating new opportunities in the digital age.

Flipkart-Myntra: Merger control between Amazon threat and short-run effects on the Indian economy

Mergers and Acquisitions have been the most popular means of inorganic expansion of companies. It is extensively used for restructuring business organizations. The growing number of internet users, a more secure and convenient transaction system, coupled with lucrative offers and a 24x7 delivery system are the common drivers of growth. For Indian companies wishing to expand beyond India’s borders, mergers and acquisitions have become a popular method to access new markets rapidly.The immediate economic effects include potential job creation and increased investment in technology and infrastructure. With Flipkart raising $1 billion in fresh funds and Amazon pouring $2 billion into the Indian market, many existing players could fall off the investors' radar paving the way for a race between Amazon and Flipkart in India. The 2014 merger between Flipkart and Myntra marked a significant consolidation in the Indian e-commerce sector, aimed at bolstering Flipkart’s competitive stance against global rival Amazon. This paper explores the regulatory aspects of the merger control process, focusing on how the acquisition sought to mitigate the competitive threat posed by Amazon.

Barriers to innovation in Brazilian small- and medium-sized enterprises

PurposeThis research investigates the barriers impeding innovation within small- and medium-sized enterprises (SMEs) in Brazil, exploring 54 innovation-related barriers categorized into six distinct groups to offer substantial insights and analyses pertinent to the decision-makers, researchers and SMEs.Design/methodology/approachThis research employed a mixed quantitative and exploratory approach, utilizing fuzzy Delphi, fuzzy analytic hierarchy process (AHP) and fuzzy decision-making trial and evaluation laboratory (DEMATEL) methods. The fuzzy Delphi method confirmed the categories and barriers through quantitative analysis, the fuzzy AHP ranked the validated obstacles and the fuzzy DEMATEL method identified causal connections among the top-priority barriers.FindingsOut of 54 barriers, 23 significantly impacted SMEs. The “Financing and Financial” category was the most significant barrier, with “Access to Financing” being the most critical impediment. The barrier with the most influence was “Instability of Fiscal Policies,” and the highest causal priority was “Survival of the Priority Business,” identifying the government’s unstable fiscal policy as the principal barrier confronting SMEs in Brazil.Originality/valueThe primary challenges for Brazilian SMEs center on financing, fiscal policies and maintaining ongoing operations. By addressing these barriers and fostering a resilient business environment, SMEs’ innovation capabilities and competitiveness can be enhanced, serving as key drivers for sustainable economic growth in fluctuating economic conditions. This study contributes to the literature by highlighting and validating the main barriers to SME innovation, providing highly relevant information about the innovation process.

Analysis of the relationship between foreign shareholding and ESG performance of South African listed companies

Given the global movement towards sustainability and the stagnant economic growth of South Africa, this study investigates the relationship between foreign shareholding percentages and the environmental, social, and governance (ESG) scores of companies listed on the Johannesburg Stock Exchange from 2015 to 2019. With foreign investment identified as a key driver of economic growth, the study explores how ESG scores correlate with the proportion of foreign ownership, using ESG data from FTSE Russell. The data was analysed through a generalised linear mixed effects model. This study identified a positive and significant association between the overall ESG, environmental, and social scores and the percentage of foreign shareholding, respectively. Stakeholder theory suggests that companies will determine action based on the interests of all relevant stakeholders. When foreign shareholders are concerned about ESG performance, companies increase their ESG ratings, considering their current and future investors. This study is value-adding in providing evidence for governments to mandate a national transition to better ESG practices.

Analysis of Distribution Patterns and Competitiveness of the Ethnic Medicine and Healthcare Industry Using Multi-Source Data.

The healthcare industry is widely regarded as a key driver of economic growth and social development in the 21st century. This study employed multi-source data alongside hybrid analytical techniques, including Principal Component Analysis (PCA), hotspot analysis, and clustering analysis, to explore the development factors and spatial patterns of the ethnic medicine and healthcare industry (EMH) in Yunnan Province, China. The results indicate that the first five principal components account for 79.80% of the total variance, providing significant insights into the industry's competitive drivers. Using the Porter Diamond Model (PDM), spatial clustering of the EMH sector across Yunnan reveals a distinct pattern of 'one ring, two points, three areas, and multiple clusters.' The analysis further shows that industrial competitiveness is highly correlated with to the spatial distribution of regional factors, suggesting the need for a targeted development strategy: 'central innovation, western optimization, eastern enhancement, northern strengthening, and southern expansion.' These findings provide valuable recommendations for policymakers aiming to enhance the traditional and complementary medicine (T&CM) sector's contribution to regional economic development and healthcare modernisation in many parts of the world.

Synthetic CB1 Cannabinoids Promote Tunneling Nanotube Communication, Cellular Migration, and Epithelial-Mesenchymal Transition in Pancreatic PANC-1 and Colorectal SW-620 Cancer Cell Lines.

Metastasizing cancer cells surreptitiously can adapt to metabolic activity during their invasion. By initiating their communications for invasion, cancer cells can reprogram their cellular activities to initiate their proliferation and migration and uniquely counteract metabolic stress during their progression. During this reprogramming process, cancer cells' metabolism and other cellular activities are integrated and mutually regulated by tunneling nanotube communications to alter their specific metabolic functional drivers of tumor growth and progression. Here, we investigated the in vitro effects of the synthetic CB1 cannabinoids AM-404, arvanil, and olvanil on human pancreatic PANC-1 and colorectal SW-620 cancer cell lines to understand further cellular behaviors and the potential risks of their use in cancer therapy. For the first time, the synthetic CB1 cannabinoids AM-404, arvanil, and olvanil significantly altered cancer cells in forming missile-like shapes to induce tunneling nanotube (TNT) communications in PANC-1 cells. Oseltamivir phosphate (OP) significantly prevented TNT formation. To assess the key survival pathways critical for pancreatic cancer progression, we used the AlamarBlue assay to determine synthetic CB1 cannabinoids to induce the cell's metabolic viability drivers to stage migratory intercellular communication. The synthetic CB1 cannabinoids significantly increased cell viability compared to the untreated control for PANC-1 and SW-620 cells, and this response was significantly reduced with the NMBR inhibitor BIM-23127, neuraminidase-1 inhibitor OP, and MMP-9 inhibitor (MMP-9i). CB1 cannabinoids also significantly increased N-cadherin and decreased E-cadherin EMT markers compared to the untreated controls, inducing the process of metastatic phenotype for invasion. BIM-23127, MMP9i, and OP significantly inhibited CB1 agonist-induced NFκB-dependent secretory alkaline phosphatase (SEAP) activity. To confirm this concept, we investigated the migratory invasiveness of PANC-1 and SW-620 cancer cells treated with the synthetic CB1 cannabinoids AM-404, arvanil, and olvanil in a scratch wound assay. CB1 cannabinoids significantly induced the rate of migration and invasiveness of PANC-1 cancer cells, whereas they had minimal effect on the rate of migration of already metastatic SW-620 cancer cells. Interestingly, olvanil-treated SW-620 cells significantly enhanced the migration rate and invasiveness of these cells. The data support the cellular and molecular mechanisms of the synthetic CB1 cannabinoids, orchestrating intercellular conduits to enhance metabolic drivers to stage migratory intercellular communication in pancreatic cancer cells.

Modern approaches to assessing the impact on the economy and society: trends and problems

Science, Technology and Innovation (STI) are powerful drivers of economic diversification and growth, value creation and sustainable development. As geopolitical challenges and crises of the 21st Century intensify, the relevance of methods, criteria and indicators for assessing the STI policies effectiveness is increasing. Based on the results of the analysis of approaches to assessing the STI impact on the economy and society, a conclusion was drawn about the trend of their development from the econometric method and the system of quantitative indicators towards the synthesis of quantitative and qualitative analysis, the combination of patent and bibliometric analyses with thematic studies (case studies) and surveys. A comprehensive assessment of societal impacts includes a wide range of outcomes: social, cultural, environmental benefits, human health. These are covered by the 17 Sustainable Development Goals (SDGs). An important prerequisite for the effectiveness of research and innovation (R&I) policy is the transition to standards for assessing the effectiveness of programs and projects accepted in world practice: input resources (input); direct measurable results (outputs), medium-term results (outcomes), impact on the economy and society (impact), efficiency and effectiveness. The article analyzes the systems for assessing the R&I impact on the economy and society adopted in Australia and the European Union. Common to these countries is a combination of an institutional approach to finance and monitor the implementation of priority development goals through R&I projects, and a comprehensive approach to assessing the direct and indirect economic impact of R&I, supplemented by a qualitative assessing the social and environmental consequences of projects through the analysis of scientific publications and thematic reports of project implementers. An assessing the results of financing projects and programs is carried out according to the defined standards, templates and sets of indicators. The general trend is to complement the main focus on economic value with an emphasis on social needs and sustainability. However, approaches to qualitative, evidence-based assessment of the STI impacts need to be further developed, using the opportunities of digitalizing the information flows about the results and impacts of implemented projects and programs.