ABSTRACT We calculate the vorticity generation rate in the accretion disc near a slowly rotating black hole in the low-velocity, weak-field limit of general relativity. Specifically, we find that the frame-dragging effect due to the black hole’s rotation – manifested through the gravitomagnetic field – can generate vorticity in a moving plasma in the accretion disc. The mechanism remains operational as long as the accretion disc has non-negligible vertical height and is independent of the exact thermodynamical profile of the disc. The enstrophy density generation rate, as a measure of turbulence and dissipation, is presented, which indicates that the frame-dragging effect can disrupt the stability of the disc away from the z = 0 plane.