Abstract A multi-body dynamics calculation model for air suspension guide mechanism of car is established, which analyses the motion model and its application of guide mechanism on car double wishbone independent suspension by using the basic theory of rigid body motion, and then carries out kinematics analysis to make the design work rational, simple and accurate. The establishment and optimized analysis of the structure parametric design model, which is used for the objective function of minimum variation of the caster angle, kingpin inclination angle, wheel camber, wheel toe-in angle and wheel tread, gets the reasonable and optimization design scheme of structure parameters for air suspension guide mechanism, and provides a theoretical basis for further improvement of this automobile suspension system.