Since myothermic methods have been improved several attempts have been made to measure the heat liberated by the beating heart. Two observers, both experienced in the difficulties and limits of myothermic experiments, A. Y. Hill (1) and K. Bürker (2), were unable to decide how far their results showed the real change of temperature of the heart, and how far they were the effects of several sources of error. On the other hand, Herlitzka (3), Snyder (4), and Bohnenkamp (5) believed themselves entitled to draw important conclusions from their experimental results. At the suggestion, therefore, of Prof. A. V. Hill, I undertook to investigate the heat production of the heart with the various means available in his laboratory. Since, as will be shown below, my results were not in accordance with those of the last named investigators, I was forced to compare my methods with theirs. According to the most reliable of my observations I believe the warming of the heart (eel or tortoise) for a single beat to be not higher than 0·00012°. For the heart of the rabbit Herlitzka found a rise of 0·004° to 0·012°; for the terrapin’s heart Snyder found 0·00075° to 0·00255°: and for the frog’s heart Bohnenkamp found 0·001 to 0·01°. Apparatus and Methods. Galvanometer .—The galvanometer employed was designed and constructed by A. C. Downing (6). The “figure of merit” of this instrument (23,000) permitted the use of a high sensitivity, without making the deflection time when critically damped too great. With a sensitivity from 1·2 X 10 -9 to 1·3 X 10 -10 amps. per mm. the galvanometer had a complete period from 0·6 to 2·5 secs. The four coils, each of resistance 6·6 ohms, could be placed in series, or parallel, or series-parallel, so that the resistance of the galvanometer as a whole could be made to approximate to that of the thermopile, or thermocouple, used in the different experiments. The galvanometer was protected by a double shield of high permeability steel, as described by Hartree and Hill (7). Records were made photographically, as described by them, but with the difference that the distance of the drum was 1·30 metres and that the light from the lamp was interrupted each half-second by a shutter carried on an electro-magnet actuated by a half-second pendulum.
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