Double Perspective Research Articles

The Constellation of Risk Factors and Paraneoplastic Syndromes in Cholangiocarcinoma: Integrating the Endocrine Panel Amid Tumour-Related Biology (A Narrative Review).

Cholangiocarcinomas (CCAs), a heterogeneous group of challenging malignant tumours which originate from the biliary epithelium, are associated with an alarming increasing incidence during recent decades that varies between different regions of the globe. Thus, awareness represents the key operating factor. Our purpose was to overview the field of CCAs following a double perspective: the constellation of the risk factors, and the presence of the paraneoplastic syndromes, emphasizing the endocrine features amid the entire multidisciplinary panel. This is a narrative review. A PubMed-based search of English-language original articles offered the basis of this comprehensive approach. Multiple risk factors underlying different levels of statistical evidence have been listed such as chronic biliary diseases and liver conditions, inflammatory bowel disease, parasitic infections (e.g., Opisthorchis viverrini, Clonorchis sinensis), lifestyle influence (e.g., alcohol, smoking), environmental exposure (e.g., thorotrast, asbestos), and certain genetic and epigenetic interplays. With regard to the endocrine panel, a heterogeneous spectrum should be taken into consideration: non-alcoholic fatty liver disease, obesity, type 2 diabetes mellitus, and potential connections with vitamin D status, glucagon-like peptide 1 receptor, or the galanin system, respectively, with exposure to sex hormone therapy. Amid the numerous dermatologic, hematologic, renal, and neurologic paraneoplastic manifestations in CCAs, the endocrine panel is less described. Humoral hypercalcaemia of malignancy stands as the most frequent humoral paraneoplastic syndrome in CCAs, despite being exceptional when compared to other paraneoplastic (non-endocrine) manifestations and to its reported frequency in other (non-CCAs) cancers (it accompanies 20-30% of all cancers). It represents a poor prognosis marker in CCA; it may be episodic once the tumour relapses. In addition to the therapy that targets the originating malignancy, hypercalcaemia requires the administration of bisphosphonates (e.g., intravenous zoledronic acid) or denosumab. Early detection firstly helps the general wellbeing of a patient due to a prompt medical control of high serum calcium and it also provides a fine biomarker of disease status in selected cases that harbour the capacity of PTHrP secretion. The exact molecular biology and genetic configuration of CCAs that display such endocrine traits is still an open matter, but humoral hypercalcaemia adds to the overall disease burden.

Institutional, economic and cultural safeguards against corruption: a panel study of OECD countries

Purpose The purpose of this paper is to ascertain whether the combination of anti-corruption measures, with simultaneous impact on the institutional, economic and cultural dimensions, is associated with lower levels of corruption. Design/methodology/approach The authors have developed a research that seeks to find statistical evidence of the relationship between levels of corruption and combinations of anti-corruption measures. To test the hypotheses, the authors performed panel regression analysis using different panel estimation methods, namely, fixed effects (FE) models. Findings The results do not fully support the idea that the combination of anti-corruption measures with simultaneous impact on the institutional, economic and cultural dimensions has more impact on corruption levels than other measures taken singly, but rather that the most determining factor in preventing corruption lies in government effectiveness. Originality/value The relevance of this study lies in the shortcomings of this type of research applied to anti-corruption measures. Moreover, the development of panel data analysis makes it possible to approach the phenomenon from a double perspective, over time and in comparative terms between different countries, incorporating non-immediate effects and possible interactive effects between different anti-corruption measures.

Teacher knowledge: insights for continuing education in Southern Brazil

The pandemic caused by Covid-19 has caused education, on a global scale, to face increasing challenges in considerable aspects, from the social and economic inequality of students and teachers to the so-called learning deficit at all levels. Considering the essential dialogue between the university, through its teacher education courses and the basic education school, an applied research project was developed (participatory action research) whose theme presupposes technological innovation from a double perspective, as a means and an end. Means, through the proposed teaching methodology, integrated with technology with a view to changes and innovation in the work processes of basic education teachers when implemented. End, considering the pedagogical products generated after implementing the methodology, digital learning objects that, by nature, encompass different technologies for learning purposes. Furthermore, through the effective participation of teachers linked to the action research proposal, the results suggest the effectiveness of teaching resignification, made possible by continuing education, regarding their role as mediators and curators of the pedagogical process, aware that their knowledge of teacher involves the content, pedagogical and technological dimensions, as well as the role of information and communication technologies as an integral part of their pedagogical work.

Are agroecological cooperative supermarkets an alternative for scaling sustainable food?

The paper attempts to investigate the capacity of agroecological cooperative supermarkets in Spain to promote scaling of food products by means of a double perspective. We first employ a vertical scaling approach to analyze the issues affecting the governance and collective organization of the Cooperative Supermarket Network (CSN), set up in May 2022 and comprising eleven Spanish supermarkets. Secondly, we employ a perspective of horizontal scaling to investigate the potential for increased numbers of members, as well as the geographic and sociodemographic variables at play which limit the abovementioned scaling: to this end we use the case study of the cooperative supermarket La Osa, opened in Madrid in December 2020. We adopt a methodology based on participatory action research throughout the years 2022 and 2023, in which the research team was involved in the real processes of creation and development of the CSN or of La Osa. The study confirms the hypothesis that agroecological cooperative supermarkets constitute a formula for efficient retail distribution for scaling sustainable food in Spain. As opposed to the first-generation options for responsible consumption, these supermarkets appear to contribute to generating significant economies of scale and scope. In terms of vertical scaling, joint provision of services, as well as the gaining of political influence in society, constitute the main advantages in relation to the functioning of the CSN. While the recruitment of new members has heretofore been considered a priority in horizontal scaling, particular emphasis should also be placed on loyalty strategies targeting existing members.

Arslantepe in the foreground: The economic and social role of the large blades at the end of the 4th millennium BC

This paper focuses on the study of large blade assemblages made from chert raw materials at the site of Arslantepe VI-A period (3500–3200 BCE). By applying an analytical approach combining raw material characterization (NM-PCI protocol), technological and use-wear analyses, and experimental archaeology, we discuss our results from a double perspective. At first glance, we demonstrate the great potential that this proxy offers for the reconstruction of technical systems and routine activities in late prehistoric sites. Secondly, we highlight the contribution of large blades for understanding socio-economic dynamics in case-oriented debates. Specifically, large chert blade study provides further pieces of the puzzle to characterize technical and economic behaviors of the social group settled on the mound of Arslantepe at the end of the 4th millennium BC. At this time, a palatine complex with centralized administration and symbols of power, were tools to boost social inequality.

L’infini s’abouchant avec le fini : la poétique labyrinthique d’Henri Michaux

The infinite merging with the finite: the labyrinthine poetics of Henri Michaux This paper examines how the figure of the labyrinth helps us to grasp the particular writing of Henri Michaux. Based on a reading of Déplacements, dégagements, it will show how the aesthetic experience of wandering arises from compositional processes of the multiple. This double perspective, both poetic and aesthetic, allows us to grasp the specificity of labyrinthine wandering, which suggests the infinite within a structure that is however finite. It is not the absence of any signification, but the multiplication and proliferation of significant data, that produces wandering. Confronted with this multiplicity, the reader is not confined to a passive state of reception, but actively projects a trajectory in order to give meaning on all his perceptual details, even if this meaning remains unstable.

ROMANIAN ARCHITECTS IN ODESSA (1941-1944) AND THEIR SUBSEQUENT FATE

The topic of Holocaust is mostly mentioned in reference to Transnistria in the years of 1941-1944. Our research studies concerning the rapport between the officials and the architects/architecture during the totalitarian regimes in Romania unveiled the opportunity for us to discover new information and elements helping to give a more definite shape and enliven a plethora of issues, left neglected and even forgotten until today. A good example of the above is the activity of the Romanian architects in Odessa and their later destiny, marred almost to its end by the horrors lived through during the Second World War. Hence the main thesis of our article. Documents in the Romanian Securitate archives are assisting us to build their professional and human portrait, along with other enthralling elements, trying to find out how their lifes – both social and professional – were affected by what happened in 1941-1944. We already knew that the vast majority of Transnistria government’s officials were convinted for war crimes or crimes against the pease by the people’s court (1945-1946), but the fate of these architects remained unknown – or, at last, forgotten – until our research. Following the idea that they were simple technicians, our initial intuition was confirmed. Although they were arrested and investigated, in the end they were exonerated of any accusation related to their activity in Transnistria. However, from a double perspective – both the criminal record from 1945 and their belonging to a social class destined to disappear – they were under the Securitate’s lens for many years, having a series of both social problems and, above all, professional. Their ascension was completely blocked, they were constantly under surveillance, their involvement in other political processes was attempted, their transformation into Securitate’s collaborators was desired. The irony of fate is precisely that, relying exclusively on the documents of the former Securitate, we can recreate today the portraits of two architects who otherwise would have remained completely unknow.

Prioritizing institutional pressures, green supply chain management practices for corporate sustainable performance using best worst method

The emerging institutional concerns regarding the environmental crisis over the past decades have promoted the implementation of green initiatives within the supply chain, aiming to reduce environmental harm while maintaining efficiency. This study employed the BWM from a double perspective, aiming to identify and rank institutional pressures for GSCM practice implementation and the importance of these practices for sustainable performance in the Moroccan manufacturing industry. The study used purposive sampling to identify respondents with supply chain management expertise. A survey was distributed to 124 potential respondents, resulting in 55 responses. Data collection occurred between April and August 2022, with an effective response rate of approximately 38%. The results indicate that institutional pressure increases the likelihood of firms improving their GSCM activities. Normative pressures are found to be the main influencing factor for businesses to implement GSCM practices, while mimetic pressures are the least important. However, certain GSCM practices, such as GP, ECO-D, and IEM, remain among the top three most affected by isomorphic pressures. The study also highlights the importance of certain GSCM practices, such as IEM, GP, and ECO-D, for firms' sustainable performance. Economic outcomes are perceived as the experts' priority, followed by environmental and social performance. This research provides a theoretical and practical foundation for decision-makers seeking to identify the pressures affecting the implementation of GSCM practices along with the activities that most likely contribute to improving various aspects of sustainable performance.

Optimism As A Resource And Form Of Manifesting Positive Affectiveness In The Elderly And Young Adults Pre-Pandemic Vs Pandemic – Comparative Study

The present study represents a meta-analysis carried out using the term optimism as a form of manifestation of positive affectivity from a double perspective, namely: reporting to two periods, pre-pandemic and pandemic and to two age categories, young adults and old people. Two types of psychological intervention factors were analyzed in the mentioned categories, in the pre-pandemic period, namely, a period of financial stability vs pre-pandemic financial instability, respectively, the spectrum of the pandemic generating anxiety, illness and death as markers of emotional balance. The meta-analysis indirectly quantified the interest in scientific research regarding optimism as a psychological resource, through the number of published articles related to this psychological variable. Material and method: The study is a comparative and cross-sectional meta-analysis of articles published in the PubMed database during 2008-2011, 2016-2019 and 2020-2023. Data processing was carried out using the Microsoft Excel application. Results: The comparative analysis between young people and the elderly ones regarding the studies published in the period 2008-2011 with the psychological variable "optimism" in their study shows a 15.65 times higher number of studies in terms of articles about seniors. Also, the comparative analysis of the number of studies published in the period 2008-2023 for the two age categories is clearly in favor of the elderly, the ratio being 1 to 12.8. It is possible that this fact is due to the greater addressability of the health systems of the elderly. The comparative analysis led to the conclusion that optimism as a form of manifestation of positive affectivity was studied more frequently in the third age patients being considered an important resource for them due to its attenuation with advancing age and by diminishing personal resources as a consequence of cognitive impairment and emotional lability. In young people, optimism is a psychological component present in a greater proportion and constitutes the premises of ecological emotional and cognitive manifestations. Conclusions: The meta-analysis revealed differences regarding research interest related to optimism as a manifestation of positive affectivity in relation to the periods studied and to the mentioned age categories. In relation to optimism per se, it represents an important resource at any age and it is dependent on a series of factors that are related to the period of life but also to the situational context, without discussing the personality type of the individual and a series of co-factors (transgenerational, educational, cultural, geographical, etc.).
 

Introduction of Technology in Physical Education During and After the Pandemic

Physical education is seen as an essential subject for the development of healthy habits and well-being, in line with Sustainable Development Goal. Furthermore, the impact of technology on all aspects of life is now an undeniable reality. The field of education is no exception, and digitalisation has undoubtedly been accelerated by the emergency situation resulting from the COVID-19 pandemic. This paper aims to analyse the scientific production related to the field of physical education, technology, and the pandemic from a double perspective. A bibliometric approach was used to identify the variables of impact, collaboration, production, and dissemination. While the content analysis allowed us to delve deeper into the topics most frequently chosen by researchers, we found that the articles focused both on the circumstances experienced by practising teachers and on the adaptations made in the teaching/learning process with trainee teachers and students at different stages of education. Thus, technology has emerged as a fundamental tool in physical education during the pandemic, making it possible to develop or maintain better health and learning.

Il tempo e lo spazio, laggiù in fondo… Una doppia lettura di Leonora Carrington

This article analyzes Leonora Carrington’s Down Below from a double perspective. First, we want to offer an interpretative framework, in order to contextualize Carrington's literary production within the Surrealist avant-garde. Furthermore, the article examines the literary geographies of Carrington's writing, offering a parallel reading of Down Below with The Hearing Trumpet, focusing on the interconnection between physical space and the body, a geography made of flesh, which can be analyzed according to the hermeneutical lines of neo materialism.

GMP-Net: Graph based Missing Part Patching Network for Point Cloud Completion

Estimating the missing part is an important branch of point cloud completion research. However, the existing point cloud completion methods ignore the importance of feature differences between partial and complete point clouds, and have not further optimized the predicted missing point cloud. For this reason, we propose an effective Graph based Missing Part Patching Network (GMP-Net), which is a deep learning model that uses the power of graph convolution to predict missing part of point cloud in a patching manner. First, GMP-Net improves its feature extraction ability through double perspective contrastive learning which extracts better global features with semantic boundaries between missing and incomplete point clouds. Second, a tree structure decoder combined with graph attention is proposed to generate intermediate coarse missing points by gathering topologies from ancestors’ information. Third, we propose a new graph convolution technique that refines intermediate generation by constructing a graph between partial and missing points. This approach optimizes the generated missing points with the local feature of the partial points. Extensive experiments demonstrate the effectiveness of the proposed GMP-Net.

El proceso constituyente español de 1873: origen y fracaso de la República FederalThe Spanish constituent process of 1873: origin and failure of the Federal Republic

Abstract The Spanish constitutional project of 1873 was intended to lay the foundations of the First Spanish Republic, whose proclamation took place in the context of the abdication of King Amadeo I to the throne. In this article I approach the analysis of the constituent process from a double perspective. On the one hand, that of the methodological rule of the possibility principle, which requires the project having a minimum probability of success in order to contribute to the theory of constituent processes. On the other hand, that of theory building process tracing, which allows us to causally reconstruct the failure and identify the intervening factors. I argue that, although the particular seriousness of the political crisis that existed in Spain at the beginning of the constituent process did not necessarily condemn it to failure, as the process progressed, the worsening of these circumstances, together with the novel but also divisive nature of the project, ended up dynamiting the initial consensus.

The multifunctional LBC-Corpora: different aims depending on the user

Abstract Corpora are nowadays the primary source of many dictionaries and the core element of various platforms and information systems. Lexicographers have therefore a variety of new possibilities which were unthinkable in the past with different types of corpora available for use in the data collection phase of the lexicographic process (Flinz 2021). Not only lexicographers, but also other types of users (academics, translators, teachers, students etc.) can profit from them, especially when corpora are public and can be accessed using corpus linguistic tools (Ballestracci/Buffagni/Flinz 2020; Flinz/Farina 2020). The LBC-corpora are monolingual specialized comparable corpora, already online (http://corpora.lessicobeniculturali.net/) and, as monitor corpora (Lemnitzer/Zinsmeister 2015: 140), they will be augmented over time. They can be analysed using the open source tool NoSketchEngine (Billero 2020). The LBC-Corpora are also the lexicographic primary source of the LBC multilingual dictionary, which is in preparation: the provisional entry lists of different languages (Spanish, German, and French) are now ready (Billero/Farina/Nicolás Martínez 2020) and together with a selection of KWICS, which have been carefully selected following a quantitative-qualitative procedure (for German see Buffagni/Flinz/Ballestracci in prep.), will soon be online (Flinz et al. in prep.). The purpose of this paper is to reflect on the LBC-corpora from a double perspective: from the user of the LBC-platform and from the lexicographic team. In the first case following an overview of the principal characteristics of the LBC-Platform, the focus will be on the accessible corpora showing the tools which can be used (§ 2). In the second case the LBC-corpora will be examined in their function as a data basis for the LBC-Dictionary (§ 3). The attention will be on the data preparation phase: after discussing the procedure for the realization of the LBC-provisional lemma candidate lists, the focus will be on the adopted procedure for finding equivalence relations and for the individuation of other types of relations between the entries (synonymy, belonging to the same semantic field etc.). In § 4 the focus will be on the LBC-provisional lemma candidate lists and their related KWICs. Conclusions and an outlook to the future can be found in the last section (§ 5).

The importance of warehouses in logistics outsourcing: benchmarking the perspectives of 3PL providers and shippers

PurposeAn ever-increasing number of companies outsource logistics activities to third-party logistics (3PL) providers to beat the competition. From the buyer's (shippers') perspective, selecting the right 3PL provider is crucial, and from the 3PL provider's perspective, it is imperative to be attractive and to retain clients. To this aim, a potential lever can be physical assets, such as warehouses, which the literature has traditionally neglected. The objective is to benchmark the importance of warehouses for 3PL providers to attract/retain clients and for shippers to select the right 3PL provider.Design/methodology/approachThe authors performed an empirical investigation through interviews on dyads (3PL providers/shippers) and utilized the Best-Worst Method (BWM) to rank the criteria used in the 3PL buying process and allow the warehouse's role to emerge.FindingsResults show that the 3PL buying process consists of four phases and three evaluation steps. The selection criteria are classified into three groups: order qualifiers, order winners and retention factors. The warehouse has different levels of importance throughout the process. It appears that it can indirectly enhance the attractiveness and retention capability of 3PL providers through other selection criteria.Originality/valueBy combining the resource-based view and the customer value theory, this research extends the theory on logistics outsourcing by studying the phases of the 3PL buying process and scrutinizing the criteria used in different evaluation steps. The research adds a double perspective of analysis (3PL providers and shippers), which is missing in the literature, and focuses on the importance of warehouses.

Is the Education System Prepared for the Irruption of Artificial Intelligence? A Study on the Perceptions of Students of Primary Education Degree from a Dual Perspective: Current Pupils and Future Teachers

The recent irruption of ChatGPT, a powerful chatbot that uses a “Chat Generative Pretrained Transformer” language model, could revolutionize education worldwide since it can greatly affect the competence development that students need to achieve for their professional future. The aim of this work is to assess the level of knowledge of ChatGPT and the perception of its possibilities of use in education by students studying the Primary Education Degree at the University of León (Spain) from a double perspective: as students and future teachers, respectively. For this purpose, a descriptive, cross-sectional, non-experimental, and quantitative research design was carried out, with the design and elaboration of a questionnaire. The questionnaire data were statistically processed by calculating relative frequencies. The main results highlight that students have a positive perception of ChatGPT use, with potential applications in education, and do not perceive it as a threat to the deterioration of the educational system as long as the sources of the data generated by the tool are verified. In addition, as students and future teachers, they need more knowledge about the operation of ChatGPT to ensure its correct use and maintain the quality of the education system. Thus, to overcome ChatGPT irruption in education, digital literacy is crucial at all educational levels.

The Basque poets during the Second Republic: José María Agirre, ‘Xabier Lizardi’, and Esteban Urkiaga, ‘Lauaxeta’, in their artistic context1

This article aims to follow the trail of some of the influences in the poetic works of José María Agirre, ‘Lizardi’ (1896–1933), and Esteban Urkiaga, ‘Lauaxeta’ (1905–37), both of whom are clearly connected to Symbolism through Spanish Modernism. They are considered the modernizers of Basque poetry and are the most frequently cited examples as paradigms of the Republican era. To this end, a double perspective will be followed. In the case of Lizardi, his literary affiliations will be addressed, relating him to Juan Ramón Jiménez (1881–1958) and José Ortega y Gasset (1883–1955). In order to approach the work of Lauaxeta, we will suggest a number of similarities to the poetry of Federico García Lorca (1898–1936), and to the music of Jesús Guridi (1886–1961) and his zarzuela, El Caserío (1926). We will also establish links between his work and some Impressionist and Symbolist painters, such as Darío Regoyos (1857–1913), Valentín de Zubiaurre (1879–1963) and Aurelio Arteta (1879–1940).

The Role of Technology in Physical Education Teaching in the Wake of the Pandemic

Physical education is seen as an essential subject for the development of healthy habits and well-being, in line with Sustainable Development Goal 3. Furthermore, the impact of technology on all aspects of life is now an undeniable reality. The field of education is no exception, and digitalisation has undoubtedly been accelerated by the emergency situation resulting from the COVID-19 pandemic. This paper aims to analyse the scientific production related to the field of physical education, technology, and the pandemic from a double perspective. From a search in Scopus, 86 articles were selected for analysis. A bibliometric approach was used to identify the variables of impact, collaboration, production, and dissemination. While the content analysis allowed us to delve deeper into the topics most frequently chosen by researchers, we found that the articles focused both on the circumstances experienced by practising teachers and on the adaptations made in the teaching/learning process with trainee teachers and students at different stages of education. Thus, technology has emerged as a fundamental tool in physical education during the pandemic, making it possible to develop or maintain better health and learning.

Thomas Ebendorfer on virtus sermonis and the Relation between Theology, Philosophy, and Logic

Abstract The focus of this article is the manner in which Thomas Ebendorfer of Hasselbach, a Viennese theologian lecturing on Book I of the Sentences in 1421, deals with the topic of virtus sermonis and the relation between theology, philosophy, and logic in his Prologue from the autograph MS Wien, Österreichische Nationalbibliothek, 4369 (ff. 7r–8v). By combining a double classification of each science (into acquisita vs. infusa) with a double perspective of their relation (temporal vs. natural), and by making a strong claim for theology’s role in advancing new logical theories, Ebendorfer’s view reflects a progressive awareness of the distinction between theology and philosophy which, in turn, entails very different applications of virtus sermonis in the two sciences. An edition of the Prologue is provided in the Appendix.

IoT Facing Covid-19: A Classification Modeling

The sudden and disruptive break out of Covid-19 has a significant impact on various sectors. On the other hand, IoT solutions, with an important time and importance in the literature, offer some applications developed to mitigate the effects of the pandemic which affects worldwide. This article aims to analyze the main trends in IoT Healthcare solutions, specifically those aimed at the context of the pandemic. To this end, a systematic literature review is carried out on the main search engines available. As a result, through the classification of articles by the applicability function of "things", the scope is analyzed from a double perspective, IoT - Covid 19 and IoT - Healthcare. Additionally, the metamodeling of the main findings of the study and their respective instances is presented.