Objectives: To investigates the solutions of fourth order partial integro-differential equations with high-order non-integer derivatives and weakly singular kernels. Methods: Weakly singular kernels present challenges in both analytical and numerical treatments due to their intricate behaviour near singular points. In this article, we introduce a novel approach utilizing the double Laplace transform method to effectively address these challenges. Findings: By solving a series of precise and understandable examples, the double Laplace transform clearly transforms the fractional partial integro-differential equation into an algebraic equation that can be solved easily. Novelty: The double Laplace transform is an effective instrument for solving fractional partial integro-differential equations, which are commonly used in fields such as physics, fluid mechanics, gas dynamics, and signal processing. Mathematics Subject Classifications: 35R09, 35R11, 44A10, 44A30. Keywords: Fractional PIDE, Weakly singular kernel, Double Laplace transform, Inverse double Laplace transform, Exact solution