Farmers and herders often interface ethno-veterinary knowledge and modern veterinary to treat their livestock. Viability of livestock production in local communities is continuously under the threat due to different diseases including retained placenta. The current study documented medicinal plants used to treat retained placenta and associated diseases in Dinokana communities, North West Province, South Africa. Ethnobotanical data was collected using semi-structured interviews. The collected data was presented as percentages and frequencies, use-value, frequency of citation and cultural importance index. In the study area, 25 plants from 18 families were indicated as remedies for the treatment of retained placenta in cattle. Hypoxis hemerocallidea, Peltophorum africanum, Drimia sanguinea and Elephantorrhiza elephantina were the most cited plants. The most dominating life forms were herbs (40%) and shrubs (36%). The plant parts commonly preferred in the preparation of remedies for retained placenta included the roots (36%) and leaves (21%) and whole plant (18%). Poultice (68%), maceration (24%) and decoction (8%) were the three methods of preparation that were described by the participants. Most (68%) of plants were administered topically. As indicated by the participants, at least 20% of the 25 medicinal plants had multiple indications (uses) either as single-plant or poly-plant remedies against diseases in cattle. Apart from retained placenta in cattle, these plant remedies were used for constipation, intestinal parasites, anaemia, pain and inflammation as well as diarrhoea. The study unravelled the rich indigenous knowledge on plants with ethno-veterinary value among Dinokana communities. Further studies are needed in order to determine biological activities and safety as well as the chemical profiles for these documented plants especially for those currently lacking scientific evidence on their efficacies.