Spinal cord injury is one of the most difficult problems of modern neurosurgery. According to statistics, there are about 3,000 people with this disease in Ukraine every year. The causes of cervical spinal cord injury are traffic accidents, domestic and industrial injuries. Therefore, the main task of doctors at the current stage is the creation of physical rehabilitation programs for the successful treatment and rehabilitation of this contingent of patients. The purpose of the study is to study the changes in muscle tone in persons of II mature age with spinal cord injury of the cervical region under the influence of therapeutic physical education. Material and methods: 27 people (10 women and 17 men) with this injury participated in the study. The age of the patients is 36-46 years. The degree of spasticity was determined according to the modified 6-point Ashforth spasticity scale. Results: All patients were divided into two groups: control (13 people) and main (14 people). The physical therapy classes developed by us contributed to the reduction of spasticity of the studied muscles. Thus, the level of spasticity of the calf and soleus muscles, adductor muscles, and quadriceps muscle in the subjects of the main group is two times lower than in the patients of the control group. Conclusions. Therefore, the results of our research indicate that physical therapy exercises contribute to the reduction of muscle spasticity.