Background: The hepatitis A virus is one of the most frequent causes of foodborne infection in Bulgaria. Public health interventions that prevent mortality and morbidity have greatly increased over the past decade. Immunization is one of these preventive interventions, with a potential to bring economic benefits beyond just health benefits. Aims: To identify the possible risk factors associated with the occurrence of outbreak of hepatitis A in rural community in Bulgaria and provide recommendations for control and prevention of the disease and to prevent its recurrence. Methods: This study investigated an outbreak of viral hepatitis A in a rural community of Iscra, a small villagein SouthernBulgaria, during January-March 2012. Hundredtwenty-six blood samples, 10 water samples and 42 food samples were collected. Serum samples were tested for IgM and IgG anti HAV and IgM and IgG anti HEV antibodies. Results:125 people are infected with 69 men (86.25%) and 56 women (13.75%). at a large number of infected in age group 15-19 years (28.75%), followed by 5-9 years (18.74%). The epidemic curve showed occurrence of a peak every 4 to 6 weeks.The identified risk factors was contact with jaundice case (OR = 2.46, 95% CI = 1.39-4.36) and this risk increased further in the group of close relatives (OR = 7.79, 95% CI = 1.10-67.13). Accidents were frequently found in water system supplying drinking water to the village. There were no sewerage system and treatment plant in the village. Five hundred contact persons were followed up and tested, and three hundred and sixty of them were vaccinated. Conclusions: This epidemic is an exacerbation of a common source as well as a person-to-person transmission. Future similar outbreaks could be prevented mainly by water source control. It is necessary to increase the requirements for measures of social and domestic hygiene. It is recommended to conducthealth education, specific immunization and food safety will give the best result for disease prevention.
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